Results 61 to 70 of about 28,792 (217)

Agranulocytosis Associated with Topiramate: A Case Report and Review of Published Cases

open access: yesCase Reports in Hematology, 2018
A 41-year-old female presented to the hospital with sore throat and shortness of breath. She was hypoxic with an oxygen saturation of 87% in room air. Physical examination revealed swollen uvula with exudates.
Saroj Lohani   +3 more
doaj   +1 more source

Fosfomycin-induced agranulocytosis: a case report and review of the literature

open access: yesBMC Infectious Diseases, 2023
Background The intravenous form of fosfomycin, a bactericide antibiotic used to treat multiresistant bacterial infections is little prescribed. The most common reported adverse effects are hypokaliemia and hypernatremia.
Elodie Matusik   +9 more
doaj   +1 more source

Evaluation of preclinical antipsychotic models used to support first‐in‐human clinical trials

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 7, Page 1364-1389, April 2026.
Abstract Schizophrenia is regarded as a complex and heterogeneous psychiatric disorder, characterised by diverse symptoms and comorbidities, which complicate both clinical management and drug development. Current pharmacological treatment, primarily based on dopamine D2 receptor antagonism or partial agonism, which has not markedly progressed since the
Thi Viet Ha Nguyen   +2 more
wiley   +1 more source

Neutropenia, agranulocytosis and dipyrone

open access: yesSão Paulo Medical Journal
CONTEXT: Neutropenia and agranulocytosis may be defined as granulocyte counts of less than 1,500/mm³ and 500/mm³, respectively. Agranulocytosis is a rare and serious disease often caused by drugs. Its mortality rate is around 10%.
Nelson Hamerschlak   +1 more
doaj   +1 more source

Captopril-Associated Agranulocytosis - a Report of 3 Cases [PDF]

open access: yes, 1991
Three cases of captopril-associated neutropenia are described, which illustrate the clinical presentation, variable predisposing factors and outcome of this rare but potentially serious adverse event. Particular risk factors of renal failure and collagen
Koopowitz, A., Pillans, P. I.
core  

Maternal Analgesic Exposure and Fetal Ductal Constriction: A Prospective Cohort Study in Late Pregnancy

open access: yesBirth Defects Research, Volume 118, Issue 3, March 2026.
ABSTRACT Objective To evaluate the association between maternal analgesic exposure in late pregnancy and fetal ductal and pulmonary hemodynamics using serial echocardiographic assessment, and to explore potential differences between metamizole and acetaminophen. Methods In this prospective cohort study, 67 third‐trimester pregnancies were evaluated: 47
Isaura Elaine Gonçalves Moreira Rocha   +5 more
wiley   +1 more source

Decoding Clozapine-Induced Agranulocytosis: Unraveling Interactions and Mitigation Strategies

open access: yesPharmacy
Agranulocytosis represents a severe complication associated with the administration of clozapine. Clozapine is an antipsychotic medication that has demonstrated substantial efficacy in remediating refractory schizophrenia and various other psychiatric ...
Ali Alalawi   +6 more
doaj   +1 more source

Dapsone-induced agranulocytosis leading to perianal abscess and death: a case report

open access: yesJournal of Medical Case Reports, 2011
Introduction Dapsone (diaminodiphenylsulfone) is used for the treatment of intractable skin diseases such as pemphigus and leprosy. The side effects of Dapsone are anemia, leukopenia, and liver dysfunction.
Kitamura Nobuya   +2 more
doaj   +1 more source

Impact of Thiazides and Fluoropyrimidines Interaction on Myelotoxicity and Other Adverse Events in Real‐World Practice: A Retrospective Cohort Study

open access: yesCancer Medicine, Volume 15, Issue 3, March 2026.
ABSTRACT Introduction The European Summary of Product Characteristics (SmPC) for 5‐FU warns of significant granulocyte decline when combined with thiazides, cyclophosphamide, or methotrexate, based on a 1981 cohort of 14 patients. Despite limited evidence, drug‐interaction checkers still flag this risk.
Gerard Ronda‐Roca   +5 more
wiley   +1 more source

Incidence of aplastic anemia and agranulocytosis in Latin America: the LATIN study

open access: yesSão Paulo Medical Journal
CONTEXT AND OBJECTIVE: Aplastic anemia and agranulocytosis are rare but life-threatening disorders, often caused by drugs and other environmental exposures.
Nelson Hamerschlak   +11 more
doaj   +1 more source

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