Clozapine-related neutropenia and agranulocytosis in Korea: 2025 update for rethinking the role of monitoring system [PDF]
Therapeutic Advances in PsychopharmacologyBackground: In February 2025, the FDA ended the mandatory Risk Evaluation and Mitigation Strategy requirements for clozapine. Korea continues mandatory hematologic testing under the Clozapine Patient Monitoring System (CPMS), yet no nationwide updates ...
Nuree Kang +10 more
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Metamizole-induced agranulocytosis from a German intensive care perspective [PDF]
Frontiers in MedicineBackground/objectivesMetamizole (dipyrone) is a non-opioid analgesic and antipyretic widely used in Germany, with prescriptions having increased more than tenfold since 1997.
Laura Hille +5 more
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Decoding Clozapine-Induced Agranulocytosis: Unraveling Interactions and Mitigation Strategies
PharmacyAgranulocytosis represents a severe complication associated with the administration of clozapine. Clozapine is an antipsychotic medication that has demonstrated substantial efficacy in remediating refractory schizophrenia and various other psychiatric ...
Ali Alalawi +6 more
doaj +2 more sources
Spironolactone-Induced Agranulocytosis: A Case Report [PDF]
Kaohsiung Journal of Medical Sciences, 2003 A 43-year-old woman with liver cirrhosis and hepatocellular carcinoma was admitted for the chief problem of ascites. Laboratory data revealed a leukocyte count of 3.8 × 109/L on the second day of admission.
Shu-Hwa Hsiao, May-Ying Hsu
doaj +3 more sources
Voriconazole-Induced Agranulocytosis in a Cirrhotic Patient with Influenza-Associated Pulmonary Aspergillosis: A Case Report [PDF]
Infection and Drug ResistanceXiaofei Lin, Yubin Du, Hui Mai, Xiaoling Zhang Department of Geriatrics, Huizhou First Hospital, Huizhou, Guangdong Province, Peoples’ Republic of ChinaCorrespondence: Xiaofei Lin, Email linxiaofeigd@163.comAbstract: The diagnosis and treatment of ...
Lin X, Du Y, Mai H, Zhang X
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A systematic review and pharmacovigilance analysis of the risk of agranulocytosis associated with metamizole use [PDF]
Scientific ReportsMetamizole is an analgesic widely used after its introduction but later withdrawn in several countries due to the risk of agranulocytosis. Despite this, it remains frequently used worldwide.
Alessia Zinzi +7 more
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Severe agranulocytosis in patient with Graves’ disease on second exposure to carbimazole [PDF]
Endocrinology, Diabetes & Metabolism Case ReportsFor half a century, antithyroid drugs (ATDs) have been the first-line treatment for Graves’ disease. ATDs, e.g. carbimazole, are associated with minor and serious adverse effects. These include rash, urticaria, arthralgia, hepatotoxicity, vasculitis, and
Hady M Gad +6 more
doaj +2 more sources
A rare cause of agranulocytosis [PDF]
, 2021 Clozapine, an atypical antipsychotic agent, is useful in the treatment of patients with psychotic symptoms. However, severe adverse effects, such as agranulocytosis, can restrict its indications.
Luís, Helena +3 more
core +1 more source
Ceftazidime‐Induced Agranulocytosis: A Case Report [PDF]
Clinical Case ReportsThe most common adverse events associated with ceftazidime include hypersensitivity reactions, gastrointestinal disturbances, and transient abnormal liver function tests, whereas neutropenia is a rare complication.
Bingbin Dong, Xin Wu, Changbao Huang
doaj +2 more sources
CAQ Corner: Immune‐mediated complications
, 2022 Liver Transplantation, EarlyView.
Mary Thomson, John R. Lake
wiley +1 more source