Results 91 to 100 of about 52,487 (253)
Critical Synthesis Package: Leeds Attitude Towards Concordance II Scale (LATCon II)
MedEdPORTAL, 2013 This Critical Synthesis Package contains: (1) a Critical Analysis of the psychometric properties and application to health sciences education for the Leeds Attitude Towards Concordance Scale II (LATCon II), and (2) a copy of the LATCon II developed by ...
David Way
doaj +1 more source
, 2023 Abstract Background and objective: This study aims to identify the quality of acupuncture recommendations for migraine in global headache guidelines. Methods: Global migraine guidelines published before June 2022 were searched and screened. The AGREE II (Appraisal of Guidelines for Research & Evaluation II) and AGREE-REX (The Appraisal of ...
Shuo Cui +7 more
openaire +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
, 2017 Additional file 1: Table S1. Correlation between the AGREE I and AGREE II items. *p < 0.05, **p < 0.01.
Seto, Kanako +5 more
openaire +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Quality assessment of clinical practice guidelinesfor Chagas disease
Revista da Sociedade Brasileira de Medicina Tropical, 2015 INTRODUCTION: The development of clinical practice guidelines (CPGs) has increased; this study aimed to assess the quality of CPGs for the management of Chagas disease.
Mario Javier Olivera +2 more
doaj +1 more source
Assessing the Quality of Global Clinical Practice Guidelines on Gout Using AGREE II Instrument
JCR: Journal of Clinical Rheumatology, 2018 Objective The aim of this study was to assess the quality of global clinical practice guidelines (CPGs) on gout. Methods We systematically searched MEDLINE, CBM (Chinese Biomedical Literature database), GIN (Guidelines International Network), NICE (National Institute for Health and ...
Wang, Dongke +9 more
openaire +4 more sources
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source