Results 101 to 110 of about 52,487 (253)

Author Correction: AGREE-S: AGREE II extension for surgical interventions: appraisal instrument

Surgical Endoscopy, 2022
Antoniou S. A., Florez I. D., Markar S., Logullo P., Lopez-Cano M., Silecchia G., Antoniou G. A., Tsokani S., Mavridis D., Brouwers M., Dayem Y. S. A., Bertolaccini L., Alonso-Coello P., Akl E., Chand M., Como J. J., de Borst G. J., Di Saverio S., Emile S., Eom B. W., Gorter R., Hanna G., Immonen K., Lai Q., Lumen N., Mathew J. L., Montendori A., Moya M., Pellino G., Sanabria A., Saratzis A., Smart N., Stefanidis D., Zaninotto G.   +33 more
openaire   +2 more sources

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Systematic review of clinical practice guidelines for management of idiopathic steroid-sensitive nephrotic syndrome (SSNS) in children using the AGREE II Instrument

, 2020
Our aim is report the results of the systematic review and critical appraisal of the recently published CPGs for Childhood (SSNS) using the Appraisal of Guidelines for Research and Evaluation Instrument (AGREE) II ...
Dr.Reem Al Khalifah, Khalid Alhassan, Yasser S. Amer   +2 more
core   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Process description and evaluation of Canadian Physical Activity Guidelines development

International Journal of Behavioral Nutrition and Physical Activity, 2010
Background This paper describes the process used to arrive at recommended physical activity guidelines for Canadian school-aged children and youth (5-17 years), adults (18-64 years) and older adults (≥65 years).
Tricco Andrea C, Kho Michelle E, Tremblay Mark S, Duggan Mary   +3 more
doaj   +1 more source

Application of the AGREE II instrument in the evaluation of a selection of South African Clinical Guidelines [PDF]

, 2014
Dissertation (MSc)--University of Pretoria, 2014.Guideline development processes influence the quality of clinical guidelines. The aim of this study was to use the AGREE II instrument to evaluate the variability of the quality of selected guidelines ...

core  

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

Guideline appraisal with AGREE II: Systematic review of the current evidence on how users handle the 2 overall assessments.

PLoS ONE, 2017
IntroductionThe Appraisal of Guidelines for Research & Evaluation (AGREE) II instrument is the most commonly used guideline appraisal tool. It includes 23 appraisal criteria (items) organized within 6 domains and 2 overall assessments (1.
Wiebke Hoffmann-Eßer, Ulrich Siering, Edmund A M Neugebauer, Anne Catharina Brockhaus, Ulrike Lampert, Michaela Eikermann   +5 more
doaj   +1 more source

A Critical Appraisal of the Quality of Glioma Imaging Guidelines Using the AGREE II Tool: A EuroAIM Initiative

Frontiers in Oncology, 2019
Background: Following the EuroAIM initiative to assess the quality of medical imaging guidelines by using the Appraisal of Guidelines for Research and Evaluation (AGREE) II instrument, we aimed to evaluate the quality of the current imaging guidelines in
Valeria Romeo, Arnaldo Stanzione, Lorenzo Ugga, Renato Cuocolo, Sirio Cocozza, Evangelia Ioannidou, Evangelia Ioannidou, Arturo Brunetti, Sotirios Bisdas, Sotirios Bisdas   +9 more
doaj   +1 more source

Do the clinical practice guidelines for pediatric dentistry meet the quality standards? A meta-research and quality appraisal protocol using AGREE II and AGREE REX tools.

, 2023
Clinical Practice Guidelines (CPGs) are recommendations for the health care providers and a method to close the know-do gap, transferring the knowledge from the academic research to the clinician.
Daniela Prócida Raggio, Fausto Medeiros Mendes, Tamara Kerber Tedesco, Thais Gimenez, Mariana Minatel Braga, Claudia Jacqueline Lopez Gallegos, Rokaia Elagami   +6 more
core   +1 more source