Influence of Zn2+ and Oxygen Supply on Malic Acid Production and Growth of Aspergillus oryzae
ABSTRACT Malic acid is a valuable platform chemical traditionally derived from fossil‐based resources. Microbial cultivation with Aspergillus oryzae offers a sustainable alternative based on renewable feedstocks. In this study, a well‐established minimal medium for malic acid production, commonly used in previous research to ensure reproducibility, was
Lukas Hartmann +3 more
wiley +1 more source
Impact of agricultural machinery input on agricultural green production efficiency in the YREB from a spatial spillover perspective. [PDF]
Guo S, Tang X.
europepmc +1 more source
ABSTRACT Protein aggregation poses a significant risk to biopharmaceutical product quality, as even minor amounts of oligomeric species can compromise efficacy and safety. Rapid and reliable detection of protein aggregates thus remains a major challenge in biopharmaceutical manufacturing.
Jakob Heyer‐Müller +4 more
wiley +1 more source
Understanding rice production stagnation in the Philippines: Regional evidence and development implications. [PDF]
Bartelet HA +3 more
europepmc +1 more source
Gaussian Processes for Predictive QSAR Modeling of Chromatographic Processes
ABSTRACT Chromatography is a key unit operation in the biopharmaceutical manufacturing process used for protein purification and polishing. Design and optimization of these processes are resource‐intensive resulting from the complex combinatorial design space.
Harini Narayanan +7 more
wiley +1 more source
Research on Orchard Navigation Line Recognition Method Based on U-Net. [PDF]
Xu N, Ning X, Li A, Li Z, Song Y, Wu W.
europepmc +1 more source
Transfer Learning Approaches in Bioprocess Engineering: Opportunities and Challenges
ABSTRACT Transfer learning (TL) has recently emerged as a promising approach to overcoming one of the key limitations of bioprocess engineering: data scarcity. By leveraging knowledge from one bioprocess to another, TL allows existing models and data sets to be reused efficiently, accelerating process development, improving prediction accuracy, and ...
Daniel Barón Díaz +3 more
wiley +1 more source
Resourceful utilization of crop residue by smallholder farmers in major grain-producing areas: pathways and countermeasures. [PDF]
Ge Y, Fan L.
europepmc +1 more source
ABSTRACT Stem cell‐based therapies hold transformative potential for regenerative medicine, yet their progress is constrained by persistent variability in manufacturing and clinical performance. Conventional frameworks such as Quality by Design (QbD), though effective for drugs and biologics, struggle to accommodate the dynamic nature of living cell ...
Mee‐Hae Kim, Masahiro Kino‐oka
wiley +1 more source
Unpacking the growth of global agricultural greenhouse gas emissions. [PDF]
Ortiz-Bobea A, Pieralli S.
europepmc +1 more source

