Results 231 to 240 of about 20,021 (258)

The NPY/AgRP neuron and energy homeostasis

International Journal of Obesity, 2001
Kennedy hypothesized nearly 50 y ago that negative feedback regulation of body fat stores involves hormones that circulate in proportion to adiposity and enter the brain, where they exert inhibitory effects on food intake and energy balance. Recent studies implicate leptin and insulin as 'adiposity signals' to the brain that promote negative energy ...
G J, Morton, M W, Schwartz
openaire   +2 more sources

Cannabinoids drive feeding through AgRP neurons

Brain Research
The endocannabinoid system regulates energy balance and feeding behavior, primarily through cannabinoid type-1 receptors (CB1Rs). While CB1R activation is known to increase food intake, the role of agouti-related peptide (AgRP) neurons of the arcuate nucleus (ARC) in this process remains unclear.
YILMAZ, BAYRAM, Goren, Habibe, Yavuz, Yavuz   +2 more
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Neuroendocrine Regulation by the Agouti/Agrp-Melanocortin System

Endocrine Research, 2000
(2000). Neuroendocrine Regulation by the Agouti/Agrp-Melanocortin System. Endocrine Research: Vol. 26, No. 4, pp. 571-571.
G, Barsh, T, Gunn, L, He, B, Wilson, X, Lu, I, Gantz, S, Watson   +6 more
openaire   +2 more sources

Serum agouti-related protein (AgRP) levels in bipolar disorder: Could AgRP be a state marker for mania?

Psychiatry Research, 2018
Orexigenic and anorexigenic peptides, especially agouti-related protein (AgRP) and leptin, play important roles in the regulation of energy homeostasis in bipolar disorder. AgRP regulates energy metabolism by increasing appetite and decreasing energy expenditure.
Parlak, Naci, Gorgulu, Yasemin, Cinar, Rugul Kose, Sonmez, Mehmet Bulent, Parlak, Ebru   +4 more
openaire   +3 more sources

AgRP Neurons Encode Circadian Feeding Time

Physiology
Food intake follows a predictable daily pattern and synchronizes metabolic rhythms. Neurons expressing Agouti-related protein (AgRP) read out physiological energetic state and elicit feeding, but the regulation of these neurons across daily timescales is poorly understood.
Nilufer Sayar, Iltan Aklan, Yavuz Yavuz, Connor Laule, Hyojin kim, Jacob rysted, Muhammed Ikbal Alp   +6 more
openaire   +1 more source

mTORC1 signaling in Agrp neurons mediates circadian expression of Agrp and NPY but is dispensable for regulation of feeding behavior

Biochemical and Biophysical Research Communications, 2015
Orexigenic agouti-related protein/neuropeptide Y (Agrp/NPY) neurons and an orexigenic pro-opiomelanocortin (POMC) neurons of the hypothalamus regulate feeding behavior and energy homeostasis. An understanding of the molecular signaling pathways that regulate Agrp/NPY and POMC function could lead to novel treatments for metabolic disorders.
Albert, Verena, Cornu, Marion, Hall, Michael N.   +2 more
openaire   +3 more sources

The Neuroendocrine Circuitry Controlled by POMC, MSH, and AGRP

2011
Obesity is one of the most challenging health problems worldwide. Over the past few decades, our knowledge concerning mechanisms of weight regulation has increased tremendously leading to the identification of the leptin-melanocortin pathway. The filling level of energy stores is signaled to the brain, and the information is integrated by hypothalamic ...
Heike, Biebermann, Peter, Kühnen, Gunnar, Kleinau, Heiko, Krude   +3 more
openaire   +2 more sources

Nutrient-sensing AgRP neurons relay control of liver autophagy during energy deprivation

Cell Metabolism, 2023
Hendrik Nolte, Paul Klemm, Sinika Henschke   +2 more
exaly  

AgRP

2006
openaire   +2 more sources

Agrp-negative arcuate NPY neurons drive feeding under positive energy balance via altering leptin responsiveness in POMC neurons

Cell Metabolism, 2023
Chi Kin Ip, Lei Zhang, Herbert Herzog
exaly