Structural Insights Into Acyl-ACP Selective Recognition by the Aeromonas hydrophila AHL Synthase AhyI [PDF]
BMC Microbiology, 2021 Background Aeromonas hydrophila is a gram-negative bacterium and the major causative agent of the fish disease motile aeromonad septicemia (MAS). It uses N-acyl-homoserine lactone (AHL) quorum sensing signals to coordinate biofilm formation, motility ...
Lei Jin, Wenge Yang, Jingjiao Bao
exaly +3 more sources
Hypersensitive Response of Plasmid-Encoded AHL Synthase Gene to Lifestyle and Nutrient by Ensifer adhaerens X097 [PDF]
Frontiers in Microbiology, 2017 It is known that some bacteria, especially members of the family Rhizobiaceae, have multiple N-acyl homoserine lactones (AHL) synthase genes and produce multiple AHL signals.
Yan-Hua Zeng, Yili Huang, Zhiliang Yu
exaly +4 more sources
Computational and Structural Biotechnology Journal, 2021 Acyl-homoserine lactone (AHL) is the most studied autoinducer in gram-negative bacteria controlling infections of various pathogens. Quenching of AHL signaling by inhibiting AHL synthesis or AHL-receptor binding via small molecular chemicals or ...
Tao Li, Danyu Shen, Shan-Ho Chou
exaly +3 more sources
Age-related hearing loss persisted in mice that had demonstrated improved healthspan, reduced inflammaging and extended lifespan following expression of the naked mole-rat transgene for hyaluronan synthase 2 [PDF]
Frontiers in AgingBackgroundApproximately one in three adults aged 65–74 years reports hearing difficulty, including age-related hearing loss (AHL, presbycusis). The C57BL/6 mouse is widely used in preclinical AHL research because it develops AHL relatively early. Calorie
Connor E. Owens +8 more
doaj +2 more sources
Stenotrophomonas maltophilia Responds to Exogenous AHL Signals Through the LuxR Solo SmoR (Smlt1839)
Frontiers in Cellular and Infection Microbiology, 2015 Quorum Sensing (QS) mediated by Acyl Homoserine Lactone (AHL) molecules are probably the most widespread and studied among Gram-negative bacteria. Canonical AHL systems are composed by a synthase (LuxI family) and a regulator element (LuxR family), whose
Xavier Daura +2 more
exaly +3 more sources
Homocysteine thiolactone from translation proofreading is an endogenous ligand for cell-cell signaling by the receptor SdiA [PDF]
mBioSeveral widespread mechanisms enable cellular communication and coordinate the behavior of bacterial populations. The modules responsible for cellular communication are often found in matching pairs: an enzyme that synthesizes a signal molecule and a ...
Lorenzo Eugenio Leiva +3 more
doaj +2 more sources
A covariation analysis reveals elements of selectivity in quorum sensing systems
eLife, 2021 Many bacteria communicate with kin and coordinate group behaviors through a form of cell-cell signaling called acyl-homoserine lactone (AHL) quorum sensing (QS). In these systems, a signal synthase produces an AHL to which its paired receptor selectively
Samantha Wellington Miranda +6 more
doaj +1 more source
Identification of a solo acylhomoserine lactone synthase from the myxobacterium Archangium gephyra
Scientific Reports, 2021 Considered a key taxon in soil and marine microbial communities, myxobacteria exist as coordinated swarms that utilize a combination of lytic enzymes and specialized metabolites to facilitate predation of microbes.
Hanan Albataineh +4 more
doaj +1 more source
Phenotypic and genotypic characterisation of Burkholderia cenocepacia J2315 mutants affected in homoserine lactone and diffusible signal factor-based quorum sensing systems suggests interplay between both types of systems. [PDF]
PLoS ONE, 2013 Many putative virulence factors of Burkholderia cenocepacia are controlled by various quorum sensing (QS) circuits. These QS systems either use N-acyl homoserine lactones (AHL) or cis-2-dodecenoic acid ("Burkholderia diffusible signal factor", BDSF) as ...
Claudia Udine +7 more
doaj +1 more source
The Systematic Investigation of the Quorum Sensing System of the Biocontrol Strain Pseudomonas chlororaphis subsp. aurantiaca PB-St2 Unveils aurI to Be a Biosynthetic Origin for 3-Oxo-Homoserine Lactones. [PDF]
PLoS ONE, 2016 The shoot endophytic biocontrol strain Pseudomonas chlororaphis subsp. aurantiaca PB-St2 produces a wide range of exoproducts, including enzymes and antibiotics. The production of exoproducts is commonly tightly regulated.
Judith S Bauer +5 more
doaj +1 more source