Results 11 to 20 of about 6,474 (182)

Identification of AHL Synthase in Desulfovibrio vulgaris Hildenborough Using an In-Silico Methodology

Catalysts, 2023
Sulfate-reducing bacteria (SRB) are anaerobic bacteria that form biofilm and induce corrosion on various material surfaces. The quorum sensing (QS) system that employs acyl homoserine lactone (AHL)-type QS molecules primarily govern biofilm formation.
Abhilash Kumar Tripathi, Dipayan Samanta, Priya Saxena, Payal Thakur, Shailabh Rauniyar, Kian Mau Goh, Rajesh Kumar Sani   +6 more
openaire   +4 more sources

Non-antibiotic quorum sensing inhibitors acting against N-acyl homoserine lactone synthase as druggable target [PDF]

Scientific Reports, 2014
YesN-acylhomoserine lactone (AHL)-based quorum sensing (QS) is important for the regulation of proteobacterial virulence determinants. Thus, the inhibition of AHL synthases offers non-antibiotics-based therapeutic potentials against QS-mediated bacterial
A Dürig, B Prithiviraj, C Fuqua, C Niu, C-L Koh, C-Y Chang, CA Ortori, CM Wu, D Martinelli, E Déziel, G Brackman, G Jones, J Chung, JC Taganna, JE González, KH McClean, LCM Antunes, LM Guzman, M Cámara, M Hentzer, M Manefield, M Manefield, M Ndagijimana, MBK Bandara, ME Shirtliff, MK Winson, MR Parsek, MR Parsek, MW Calfee, P Williams, R Daniels, R García-Contreras, S Swift, S Uroz, T Das, T Krishnan, T Maeda, T Rudrappa, TA Gould, TA Gould, TT Hoang, VE Wagner, WT Watson, Y-H Lin, YH Dong, YH Dong, YM Chong   +46 more
core   +4 more sources

Cultivation-Based Detection of a Novel High-GC Nitrospira Derived From the Argentinian Copahue Volcano Area. [PDF]

Environ Microbiol
In this cultivation‐based study, two novel moderately thermophilic Nitrospira enrichments were obtained from the geothermal field Las Máquinas in the Neuquén Province, Argentina. Both nitrite oxidizers, belonging to lineage V or the novel taxonomic lineage VIII, contain quorum‐sensing genes and a high genome GC content of 60.6% and 69.4%.
Spieck E, Koch H, Kop LFM, Keuter S, Malinowski M, Sass K, Sand W, Donati E, Garcia PP, Lücker S, Giaveno A.   +10 more
europepmc   +2 more sources

Unravelling the genome of long chain N-acylhomoserine lactone-producing Acinetobacter sp. strain GG2 and identification of its quorum sensing synthase gene [PDF]

, 2015
Myriad proteobacteria use N-acyl homoserine lactone (AHL) molecules as quorum-sensing (QS) signals to regulate different physiological functions, including virulence, antibiotic production and biofilm formation.
Chong-Lek Koh, Choon-Kook Sam, Kah Yan How, Kar-Wai Hong, Kok-Gan Chan, Wai-Fong Yin   +5 more
core   +12 more sources

Insights into β-ketoacyl-chain recognition for β-ketoacyl-ACP utilizing AHL synthases [PDF]

Chemical Communications, 2018
The design, synthesis and kinetic evaluation of beta-ketoacyl-ACP mimics for two 3-oxoacyl-ACP utilizing quorum signal synthases are reported.
Mila Nhu Lam, Dastagiri Dudekula, Bri Durham, Noah Collingwood, Eric C. Brown, Rajesh Nagarajan   +5 more
openaire   +3 more sources

The Systematic Investigation of the Quorum Sensing System of the Biocontrol Strain Pseudomonas chlororaphis subsp. aurantiaca PB-St2 Unveils aurI to Be a Biosynthetic Origin for 3-Oxo-Homoserine Lactones. [PDF]

PLoS ONE, 2016
The shoot endophytic biocontrol strain Pseudomonas chlororaphis subsp. aurantiaca PB-St2 produces a wide range of exoproducts, including enzymes and antibiotics. The production of exoproducts is commonly tightly regulated.
Judith S Bauer, Nils Hauck, Lisa Christof, Samina Mehnaz, Bertolt Gust, Harald Gross   +5 more
doaj   +1 more source

A Novel and Efficient Platform for Discovering Noncanonical Quorum-Quenching Proteins

Microbiology Spectrum, 2023
Quorum sensing (QS) is a well-known chemical signaling system responsible for intercellular communication that is widespread in bacteria. Acyl-homoserine lactone (AHL) is the most-studied QS signal.
Jinxing Liao, Zihan Li, Dan Xiong, Danyu Shen, Lu Wang, Xiaolong Shao, Tao Li, Guoliang Qian   +7 more
doaj   +1 more source

The autoinducer synthases LuxI and AinS are responsible for temperature-dependent AHL production in the fish pathogen Aliivibrio salmonicida [PDF]

BMC Microbiology, 2015
Quorum sensing (QS) is a cell-to-cell communication system used by bacteria to regulate activities such as virulence, bioluminescence and biofilm formation. The most common QS signals in Gram-negative bacteria are N-acyl-homoserine lactones (AHLs). Aliivibrio salmonicida is the etiological agent of cold water vibriosis in Atlantic salmon, a disease ...
Hansen, Hilde, Purohit, Amit Anand, Leiros, Hanna-Kirsti S., Johansen, Jostein, Kellermann, Stefanie J., Bjelland, Ane Mohn, Willassen, Nils Peder   +6 more
openaire   +4 more sources

Oridonin Attenuates Burkholderia cenocepacia Virulence by Suppressing Quorum-Sensing Signaling

Microbiology Spectrum, 2022
Burkholderia cenocepacia is a human opportunistic pathogen that mostly employs two types of quorum-sensing (QS) systems to regulate its various biological functions and pathogenicity: the cis-2-dodecenoic acid (BDSF) system and the N-acyl homoserine ...
Xia Li, Kai Wang, Gerun Wang, Binbin Cui, Shihao Song, Xiuyun Sun, Yinyue Deng   +6 more
doaj   +1 more source

Acyl-homoserine lactone recognition and response hindering the quorum-sensing regulator EsaR. [PDF]

PLoS ONE, 2014
During quorum sensing in the plant pathogen Pantoea stewartii subsp. stewartii, EsaI, an acyl-homoserine lactone (AHL) synthase, and the transcription factor EsaR coordinately control capsular polysaccharide production.
Daniel J Schu, Jessica M Scruggs, Jared S Geissinger, Katherine G Michel, Ann M Stevens   +4 more
doaj   +1 more source