Acyl-group specificity of AHL synthases involved in quorum-sensing in Roseobacter group bacteria [PDF]
Beilstein Journal of Organic Chemistry, 2018 N-Acylhomoserine lactones (AHLs) are important bacterial messengers, mediating different bacterial traits by quorum sensing in a cell-density dependent manner.
Lisa Ziesche +3 more
doaj +3 more sources
Specificity of Signal-Binding via Non-AHL LuxR-Type Receptors. [PDF]
PLoS ONE, 2015 Quorum sensing is a typical communication system among Gram-negative bacteria used to control group-coordinated behavior via small diffusible molecules dependent on cell number.
Sophie Brameyer, Ralf Heermann
doaj +2 more sources
An Experimentally Verified Mechanistic Model for Predicting Quorum Sensing-Based Switches. [PDF]
Microb BiotechnolA predictive model was developed to fine‐tune EsaI/EsaR quorum sensing circuits, highlighting the transcription factor's pivotal role and offering a foundation for broader applications across LuxR‐family systems in synthetic biology. ABSTRACT Quorum sensing‐based genetic circuits are gaining traction in synthetic biology as they link population‐level ...
De Baets J, De Mey M, De Paepe B.
europepmc +2 more sources
Relay Architectures and Ecological Strategies of Quorum Sensing Effects on Microbial Interactions [PDF]
Environ MicrobiolQuorum‐sensing activity in one population affects neighbouring populations through direct signal perception, QS‐regulated chemical effectors, or host‐ or environment‐mediated relays. Across distinct habitats, these relay architectures are associated with ecological strategies ranging from shared signal accessibility and reciprocal responsiveness to ...
Liang C +5 more
europepmc +2 more sources
Insights into β-ketoacyl-chain recognition for β-ketoacyl-ACP utilizing AHL synthases [PDF]
Chemical Communications, 2018 The design, synthesis and kinetic evaluation of beta-ketoacyl-ACP mimics for two 3-oxoacyl-ACP utilizing quorum signal synthases are reported.
Mila Nhu Lam +5 more
openaire +3 more sources
The characterization of a new stabilized lactonase from the endophytic fungi Aspergillus pseudonomiae with anti-bacterial and anti-fungal properties. [PDF]
Protein SciAbstract Microorganisms use diverse small‐molecule signals to coordinate behavior, supporting interspecies and interkingdom communication. These chemical dialogs shape fundamental biological processes and define interactions from cooperation to antagonism.
Ben Tovim D +4 more
europepmc +2 more sources
The autoinducer synthases LuxI and AinS are responsible for temperature-dependent AHL production in the fish pathogen Aliivibrio salmonicida [PDF]
BMC Microbiology, 2015 Quorum sensing (QS) is a cell-to-cell communication system used by bacteria to regulate activities such as virulence, bioluminescence and biofilm formation. The most common QS signals in Gram-negative bacteria are N-acyl-homoserine lactones (AHLs). Aliivibrio salmonicida is the etiological agent of cold water vibriosis in Atlantic salmon, a disease ...
Hansen, Hilde +6 more
openaire +4 more sources
A Novel and Efficient Platform for Discovering Noncanonical Quorum-Quenching Proteins
Microbiology Spectrum, 2023 Quorum sensing (QS) is a well-known chemical signaling system responsible for intercellular communication that is widespread in bacteria. Acyl-homoserine lactone (AHL) is the most-studied QS signal.
Jinxing Liao +7 more
doaj +1 more source
Oridonin Attenuates Burkholderia cenocepacia Virulence by Suppressing Quorum-Sensing Signaling
Microbiology Spectrum, 2022 Burkholderia cenocepacia is a human opportunistic pathogen that mostly employs two types of quorum-sensing (QS) systems to regulate its various biological functions and pathogenicity: the cis-2-dodecenoic acid (BDSF) system and the N-acyl homoserine ...
Xia Li +6 more
doaj +1 more source
Acyl-homoserine lactone recognition and response hindering the quorum-sensing regulator EsaR. [PDF]
PLoS ONE, 2014 During quorum sensing in the plant pathogen Pantoea stewartii subsp. stewartii, EsaI, an acyl-homoserine lactone (AHL) synthase, and the transcription factor EsaR coordinately control capsular polysaccharide production.
Daniel J Schu +4 more
doaj +1 more source