Results 51 to 60 of about 688,717 (308)

Investigating a Curcumin-Loaded PLGA-PEG-PLGA Thermo-Sensitive Hydrogel for the Prevention of Alzheimer’s Disease

Antioxidants, 2022
In Alzheimer’s disease (AD), the most common cause of dementia, patients generally forget to take pills or skip medication due to side effects, affecting the treatment efficacy.
Yi-Wen Lin, Chih-Hsiang Fang, Ching-Yun Yang, Ya-Jyun Liang, Feng-Huei Lin   +4 more
doaj   +1 more source

Different tensile tests on difference of strength of frozen soils

Yantu gongcheng xuebao, 2019
The tensile strength of frozen soils is an important index in engineering design. In the tests, it is found that the uniaxial tensile strength of frozen soils is inconsistent with the four-point bending tensile strength.
YU Chang-yi 1, 2, 3, LIU Ai-min 1, 2, 3, GUO Bing-chuan 2, LIU Wen-bin 1, 2, 3
doaj   +1 more source

Preasymptotic Convergence of Randomized Kaczmarz Method [PDF]

, 2017
Kaczmarz method is one popular iterative method for solving inverse problems, especially in computed tomography. Recently, it was established that a randomized version of the method enjoys an exponential convergence for well-posed problems, and the ...
Agaskar A, Bangti Jin, Elfving T, Golub G H, Gower R M, Ito K, Jin Q, Jin Q, Johnson R, Kaczmarz S, Kowar R, Leitão A, Li Q, Morozov V A, Natterer F, Needell D, Schöpfer F, Wang C, Xiliang Lu, Yuling Jiao   +19 more
core   +2 more sources

Optimization and Abstraction: A Synergistic Approach for Analyzing Neural Network Robustness

, 2019
In recent years, the notion of local robustness (or robustness for short) has emerged as a desirable property of deep neural networks. Intuitively, robustness means that small perturbations to an input do not cause the network to perform ...
Bastani Osbert, Gao Sicun, Gehr Timon, Goodfellow Ian J., Gopinath Divya, He Kaiming, Julian Kyle D., Katz Guy, Krizhevsky Alex, Martinez-Cantin Ruben, Pulina Luca, Scheibler Karsten, Si Xujie, Wang Shiqi   +13 more
core   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Emotion Recognition Using PPG Signals of Smartwatch on Purpose of Threat Detection

Sensors
This paper proposes a machine learning approach to detect threats using short-term PPG (photoplethysmogram) signals from a commercial smartwatch. In supervised learning, having accurately annotated training data is essential.
Gyuwon Hwang, Sohee Yoo, Jaehyun Yoo
doaj   +1 more source

Comunicação inter-específica e o seu efeito na taxa de mutação [PDF]

, 2009
Tese de mestrado, Biologia (Biologia Evolutiva e do Desenvolvimento), 2009, Universidade de Lisboa, Faculdade de CiênciasAs bactérias são capazes de sinalizar entre diferentes espécies pela produção e libertação de um sinal de comunicação inter ...
Afonso, Bruno Alexandre Caetano
core  

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

Exfoliative Endometrial Cytology in Embryo Donor Cows—Comparison of Sampling Localizations for the Diagnosis of Subclinical Endometritis

Veterinary Sciences, 2016
Subclinical endometritis has a major effect on the reproductive performance of dairy cows and also on the success of embryo collection. Thus it is important to minimize the number of false-negative diagnoses.
Janna Egberts, Jan Detterer, Arno Park, Sabine Meinecke-Tillmann   +3 more
doaj   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source