Results 61 to 70 of about 688,717 (308)
A QBF-based Formalization of Abstract Argumentation Semantics [PDF]
, 2013 Supported by the National Research Fund, Luxembourg (LAAMI project) and by the Engineering and Physical Sciences Research Council (EPSRC, UK), grant ref.
Arieli, Ofer, Caminada, Martin W.A.
core +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Yantu gongcheng xuebao, 2021 Soil cracks are often considered to be caused by tensile-shear stress. In actual engineering, the compacted clay is mostly under compressive-shear stress state.
HUANG Shi-yuan 1, 2, 4, WANG Jun-jie 2, WANG Ai-guo 3, JI En-yue 1, GUO Wan-li 1, JIN Song-yang 2
doaj +1 more source
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
Real-Time Detection of At-Risk Movements Using Smartwatch IMU Sensors
Applied SciencesThe issue of personal safety for crime prevention has become a significant societal concern. Existing software on smartwatches developed for personal protection might provide GPS location tracking and emergency reporting, but this is limited to ...
Haeun Oh, Jaehyun Yoo
doaj +1 more source
Learning the Condition of Satisfaction of an Elementary Behavior in Dynamic Field Theory
Paladyn, 2015 In order to proceed along an action sequence, an autonomous agent has to recognize that the intended final condition of the previous action has been achieved. In previous work, we have shown how a sequence of actions can be generated by an embodied agent
Luciw Matthew +4 more
doaj +1 more source
Challenges for an Ontology of Artificial Intelligence [PDF]
, 2019 Of primary importance in formulating a response to the increasing prevalence and power of artificial intelligence (AI) applications in society are questions of ontology. Questions such as: What “are” these systems? How are they to be regarded?
Hawley, Scott H.
core +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source