Results 81 to 90 of about 98,954,750 (292)
Understanding mobility choices in Australia’s driverless future: A mixed logit modelling study
Transportation Research Interdisciplinary PerspectivesThe anticipated introduction of driverless vehicle mobility in Australia from 2027 underscores the need to better understand user preferences and evolving travel behaviours. Conventional classifications such as ‘owned only’, ‘shared only’, or ‘bus riding
Asif Faisal +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Uncanny Semantics. How AI and Human Authors Use Language Differently in Academic Writing
This study explores the semantic differences between human-written and AI-generated academic texts by applying word embedding techniques to a curated corpus of 325 introductions from linguistic articles.
Wegerhoff, Dennis
core +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
THE "AI DEBATE" : ARGUMENTS AGAINST AI [PDF]
, 1994 P(論文)この論文で,AI論争においていわゆる反対陣営の交わす反論の哲学的内容を調べてみた。AIの実現にあたって次々に出てくる難問に対する理解を深めるのにはこの反論は重要な役割を果たしている。John CastiはAIの概念に対する反論の哲学的内容を三つの題目にまとめている。即ち,反行動的反論,現象学的反論,そして論理的反論である。これは,人間の頭脳にみられる認識状態と同等な状態を備えた機械(計算器)が理論的に作れるとする高度な人間的機能を持つAI理論に対して批判的な立場にある哲学者の主張である。ここで,
スロビック, H.G. +2 more
core
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
<p>Changes:</p> <ul> <li>Add built-in support for additional datasets (<a href="https://github.com/AI-SDC/AI-SDC/pull/257">#257</a>)</li> <li>Remove references to final score in outputs (<a href="https://
Albashir, Maha +8 more
core +1 more source