Results 71 to 80 of about 4,949,132 (268)
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
Open PhilosophyThe rise of self-driving cars raises numerous ethical conundrums, none has attracted so much public attention as the question of how to programme AVs in crash scenarios. How does a car respond when difficult, life-and-death choices are to be made?
Milford Stephen R. +2 more
doaj +1 more source
Theories and Dimensions of Algorithmic Power, between Agency and Domination
Scienza & PoliticaThis article reviews the critical and sociological literature on algorithms and AI in light of anthropocentric social theories of power and its dimensions.
Massimo Airoldi
doaj +1 more source
CAHRS Partners\u27 Implementation of Artificial Intelligence [PDF]
, 2018 [Excerpt] The ideas and uses for Artificial Intelligence (AI) are abundant, and each business is seemingly ripe for disruption, including HR. As the hype surrounding AI continues to be championed by popular press, we began our research in order to ...
Lee, Hannah +2 more
core +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
FEBS Open Bio, EarlyView.This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel +4 more
wiley +1 more source
Ethics of Artificial Intelligence Demarcations
, 2019 In this paper we present a set of key demarcations, particularly important when discussing ethical and societal issues of current AI research and applications.
A Etzioni +13 more
core +1 more source
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
FEBS Open Bio, EarlyView.Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system
FEBS Open Bio, EarlyView.An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková +3 more
wiley +1 more source
RHS Revista Humanismo y SociedadThis study examines how AI can be used to improve higher education students’ ability to learn effectively. The research focuses on using AI to enhance metacognition, which is the students’ ability to understand and control their learning processes ...
Nacereddine Mazari
doaj +1 more source