Results 61 to 70 of about 783,920 (240)

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

What Links Retail to Modernity? The Future of Retail - Romanian Case Study A combined Analysis of Consumer Perceptions and AI Insights

Romanian Economic Journal
This study examines the link between retail and modernity and bring as case study the Romanian perception of the future of the store. The research combines insights from secondary data consumer perception study with the potential applications of AI ...
Andreea Strătilă (Irimia)
doaj   +1 more source

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

FEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee, Ga Seul Lee, JinHan Kim, Kwang‐Hyun Park, Seong‐Ryung Go, Jeong Hee Moon, Eui‐Jeon Woo   +6 more
wiley   +1 more source

Can and Should AI Help Us Quantify Philosophical Health?

Open Philosophy
We explore the potential and limitations of using artificial intelligence to quantify philosophical health. Philosophical health is an approach to well-being defined as the dynamic coherence between thoughts, values, and actions in harmony with the world.
de Miranda Luis
doaj   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source

AI tools and cognitive lexicology in language education: A cross-linguistic perspective [PDF]

Training, Language and Culture
The paper looks at several conceptual questions in contemporary cognitive lexicology and considers how recent AI tools can be brought into language teaching in a way that does more than automate routine tasks.
Maral B. Nurtazina, Galina N. Trofimova, Jindřich Kesner   +2 more
doaj   +1 more source

AI gossip

Ethics and Information Technology
Abstract Generative AI chatbots like OpenAI's ChatGPT and Google's Gemini routinely make things up. They "hallucinate" historical events and figures, legal cases, academic papers, non-existent tech products and features, biographies, and news articles.
Joel Krueger, Lucy Osler
openaire   +2 more sources

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

Ensemble Weights-Based Geospatial Model for Optimal Allocation of Wind Turbines: A Case Study in Wasit, Iraq

Civil and Environmental Engineering
Accurate spatial decision-making models are increasingly needed for wind energy planning as the globe rushes towards carbon-neutral energy. This research aims to improve existing decision-making approaches by proposing an ensemble weight-based model for ...
Sachit Mourtadha Sarhan
doaj   +1 more source