Results 51 to 60 of about 4,949,132 (268)

Communities of knowledge and knowledge of communities: An appreciative inquiry into rural wellbeing [PDF]

open access: yes, 2014
This article offers a retrospective examination of the use of appreciative inquiry (AI) in a study on rural wellbeing. It provides a reflection on the rationale for choosing AI as a suitable methodology, critiques the application of AI in rural settings ...
Kevany, Kathleen May   +1 more
core   +3 more sources

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

AI-Generated Fashion Designs: Who or What Owns the Goods? [PDF]

open access: yes, 2020
As artificial intelligence (“AI”) becomes an increasingly prevalent tool in a plethora of industries in today’s society, analyzing the potential legal implications attached to AI-generated works is becoming more popular. One of the industries impacted by
Dennis, Caen A.
core   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Building Ethically Bounded AI

open access: yes, 2018
The more AI agents are deployed in scenarios with possibly unexpected situations, the more they need to be flexible, adaptive, and creative in achieving the goal we have given them.
Mattei, Nicholas, Rossi, Francesca
core   +1 more source

Little ai, Big AI—Good AI, Bad AI [PDF]

open access: yesResearch-Technology Management, 2019
The real risk with AI isn’t malice but competence. A super intelligent AI will be extremely good at accomplishing its goals, and if those goals aren’t aligned with ours, we’re in real trouble.
openaire   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Human, too human? Experience, Learning, Interaction with AI

open access: yesAcademicus International Scientific Journal
The contribution addresses the topic of interaction with AI with the aim of investigating the importance of interface characteristics for the acceptance of and interaction with produced innovations, with a special focus on social robotics.
Eleonora Sparano
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

AFCC 2023: The Role of the Translator in the Age of AI

open access: yesWriting Chinese: A Journal of Contemporary Sinophone Literature
The following is a record of the session “The Role of the Translator in the Age of AI” at the Asian Festival of Children’s Content, in Singapore, on 28 May 2023, a few months after the launch of ChatGPT (November 2022).
Helen Wang
doaj   +1 more source

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