Results 41 to 50 of about 180,460 (261)

General-purpose AI regulation and the European Union AI Act

Internet Policy Review
This article provides an initial analysis of the EU AI Act's (AIA) approach to regulating general-purpose artificial intelligence (AI) – such as OpenAI's ChatGPT – and argues that it marks a significant shift from reactive to proactive AI governance ...
Oskar J. Gstrein, Noman Haleem, Andrej Zwitter   +2 more
doaj   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Artificial intelligence and AI act: From the individual to the algorithm? [PDF]

Zbornik Radova: Pravni Fakultet u Novom Sadu
This paper focuses on the analysis of the AI Act as a risk-based regulatory model for AI aimed at balancing the need for technological development, which can ensure greater efficiency and well-being, with the protection of fundamental rights, for which ...
Gasparri Wladimiro, Tesi Francesca
doaj   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

The EU AI Act and the Food System: How the European Union Ai Act Applies to Agrifood

European Journal of Risk Regulation
Artificial Intelligence (AI) is increasingly being used in the agrifood sector to improve efficiency, safety and sustainability. The application of the European Union Artificial Intelligence Act’s (AI Act) to the broad spectrum of agrifood AI systems has
Idse Lucien Val
doaj   +1 more source

Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk

Molecular Oncology, EarlyView.
Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley   +1 more source

Truly Risk-based Regulation of Artificial Intelligence How to Implement the EU’s AI Act

European Journal of Risk Regulation
The Artificial Intelligence Act (AI Act) of the European Union (EU) claims to be based on a risk-based approach to avoid over-regulation and to respect the principle of legislative proportionality.
Martin Ebers
doaj   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

AI ACT AND THE ECHO OF ASIMOV'S LAWS OF ROBOTICS. WHEN THE LACK OF LEGAL SOURCES PUSHED THE EU TOWARDS SCIENCE FICTION [PDF]

Challenges of the Knowledge Society
We are living in a time of rapid technological advancement, particularly in the field of AI, and more specifically, Generative AI (GAI). As GAI models increasingly permeate everyday life, the urgent need for effective regulation has become apparent. This
Sebastian BĂLĂNICĂ, Bogdan-Alin CIOFLAN   +1 more
doaj  

Avrupa Birliği Yapay Zekâ Kanunu’nun Risk Grupları ve İlgililerin Yükümlülükleri Bağlamında İncelenmesi

Ankara Hacı Bayram Veli Üniversitesi Hukuk Fakültesi Dergisi
Avrupa Birliği, gelişen teknolojiler bakımından yapmış olduğu regülasyon çalışmaları ile ön plana çıkmaktadır. Avrupa Birliği Yapay Zeka Kanunu da bu regülasyon çalışmalarından sadece birisidir.
Salih Karadeniz
doaj   +1 more source