Results 151 to 160 of about 270,105 (295)

Anti‐Obesity Pharmacotherapy and Emerging Multimodal Interventions for Obstructive Sleep Apnea

open access: yesChronic Diseases and Translational Medicine, EarlyView.
Cellular and molecular mechanisms of obesity‐related obstructive sleep apnea (OSA). ADMA: asymmetric dimethyrarginine, NLRP3: nucleotide‐binding domain, leucine‐rich repeat family, Pyrin domain containing 3, TLR: toll‐like receptors, IL‐1β: interleukin‐1β, IL‐6: interleukin‐6; LPS: lipopolysacharide, ROS: reactive oxygen species, TNF‐α.
Anish Preshy   +3 more
wiley   +1 more source

A Stacked Ensemble Multi‐Label Model for Predicting Co‐Occurring Microvascular and Macrovascular Complications in Type 2 Diabetes

open access: yesChronic Diseases and Translational Medicine, EarlyView.
Feature importance for predicting multiple diabetes complications based on a Stacking‐Classifier Chain model. Abstract Background Type 2 diabetes mellitus (T2DM) leads to severe microvascular and macrovascular complications. Traditional single‐label prediction models fail to capture their co‐occurring nature.
Maryam Zamani   +3 more
wiley   +1 more source

Patient‐ and Clinician‐Related Factors Associated With the Reduction in Opioid Use Among Adults With Chronic Non‐Cancer Pain: A Systematic Review

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Despite known risks, opioids are widely used for chronic non‐cancer pain (CNCP). Clinical guidelines now recommend deprescribing, but factors predicting success are poorly understood. This systematic review aimed to identify clinician and patient factors associated with attaining successful opioid dose reduction or discontinuation in adults with CNCP ...
Alessandra C. Marcelo   +8 more
wiley   +1 more source

Cardiorenal Outcomes of Dapagliflozin vs. Empagliflozin in Advanced Chronic Kidney Disease and Diabetes

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Target trial emulation of a multi‐institutional electronic health record network showed comparable cardiorenal effectiveness and safety of dapagliflozin versus empagliflozin in adults with type 2 diabetes and advanced‐stage chronic kidney disease.
Shih‐Hsuan Lin   +6 more
wiley   +1 more source

Developing Sustainable Innovations for Planet, Profits—And People: Mixed‐Methods Insights From the Textile Industry

open access: yesCorporate Social Responsibility and Environmental Management, EarlyView.
ABSTRACT Sustainable innovations are increasingly recognized as promising avenues for businesses to tackle global sustainability challenges, expected to deliver ecological, social, and economic benefits. Yet social outcomes at the individual level remain underexplored, raising questions about whether such innovations fully realize their sustainability ...
Lisa Hollands   +3 more
wiley   +1 more source

The Effectiveness of Psychological Treatment for Anorexia Nervosa in Adolescents: A Critical Review of Randomized Controlled Trials

open access: yesInternational Journal of Eating Disorders, EarlyView.
ABSTRACT Objective Although international treatment guidelines for eating disorders recommend varying psychological approaches for adolescents with anorexia nervosa (AN), most existing reviews have combined adolescent and adult samples, leaving the overall evidence base for this population poorly defined.
Renée A. Broersma   +7 more
wiley   +1 more source

The Impact of Emotion Coaching on Changes in Caregiver Burden and Distress Tolerance During Family‐Based Treatment

open access: yesInternational Journal of Eating Disorders, EarlyView.
ABSTRACT Objective Caregivers often experience elevated stress while supporting a loved one with an eating disorder. This study was a secondary analysis exploring changes in caregiver burden (EDSIS), distress tolerance (DTS), and emotion regulation (ERQ) during family‐based treatment (FBT) among caregivers high in expressed emotion (EE) participating ...
Rachel Kramer   +5 more
wiley   +1 more source

The Relationship Between Premorbid Weight Status and Eating Disorder Onset in Adolescents: A Longitudinal Study

open access: yesInternational Journal of Eating Disorders, EarlyView.
ABSTRACT Objective Adolescents with higher weight status (HWS; body mass index > 85th percentile adjusted for age and sex) are at greater risk of eating disorders (ED). This study examined factors associated with HWS adolescents' increased risk and how weight status interacts with other risk factors to influence ED onset. Method Australian adolescents (
Gabriela Tavella   +5 more
wiley   +1 more source

Patterns of Uptake, Engagement, and Attrition in Randomized Controlled Trials of Digital Interventions for Eating Disorders: A Systematic Review and Meta‐Analysis

open access: yesInternational Journal of Eating Disorders, EarlyView.
ABSTRACT Objective This review aimed to quantify rates of uptake (treatment initiation), adherence (program completion), and attrition (study dropout) in randomized trials of digital eating disorder (ED) interventions, and to synthesize engagement reporting practices, their consistency, and associations with clinical outcomes. Methods Randomized trials
Claudia Liu   +4 more
wiley   +1 more source

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