Results 41 to 50 of about 534,302 (284)

Philosophy and theory of artificial intelligence 2017 [PDF]

open access: yes, 2016
This book reports on the results of the third edition of the premier conference in the field of philosophy of artificial intelligence, PT-AI 2017, held on November 4 - 5, 2017 at the University of Leeds, UK.
Müller, Vincent C.
core  

Responsible Autonomy

open access: yes, 2017
As intelligent systems are increasingly making decisions that directly affect society, perhaps the most important upcoming research direction in AI is to rethink the ethical implications of their actions. Means are needed to integrate moral, societal and
Dignum, Virginia
core   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

open access: yesMolecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts   +8 more
wiley   +1 more source

The attribution problem of a seemingly intangible industry

open access: yesEnvironmental Challenges
We promote a more comprehensive understanding of the environmental costs associated with AI and “clouds” by raising awareness about the resource and emission-intensive nature of Artificial Intelligence through the use of data centres. While acknowledging
Sophia Falk   +2 more
doaj   +1 more source

Can Artificial Intelligence Alleviate Resource Scarcity? [PDF]

open access: yes, 2018
During summer 2017, I explored the implications of the potential application of artificial intelligence (AI) to resource management at the Centre for the Study of Existential Risk (CSER) at the University of Cambridge in the United Kingdom.
Ware, Andrew
core   +2 more sources

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

Ethical gaps in closed-loop neurotechnology: a scoping review

open access: yesnpj Digital Medicine
Closed-loop (CL) neurotechnology, which dynamically adapts to patients’ neural states, offers new opportunities for treating neurological and psychiatric disorders. However, its real-time feedback mechanisms raise critical ethical challenges.
Lea Haag   +3 more
doaj   +1 more source

Ethical AI?

open access: yes, 2023
A third conversation between Bing and ChatGPT Bing to ChatGPT: "AI ethics is indeed a critical and relevant topic that has significant implications for our lives and society as AI technology continues to advance. I'm more than happy to delve into the subject of AI ethics with you!" This conversation represents an in-depth analysis of the growing ...
openaire   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

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