Results 31 to 40 of about 3,481,620 (296)
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Italian Labour Law e-JournalWarehouses with complex monitoring and algorithmic management policies are rapidly expanding across the EU. This paper explores the functionalities of a Warehouse Management System (WMS) and its role in managing warehouse workers.
Thomas De Lombaert +3 more
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Integration of Soft and Hard Laws: Profiling Legal Protection for “AI for All”
International Journal of Digital Law and GovernanceThis paper analyzes the concept of “AI for All” (AIFA), exploring its theoretical foundations, challenges, and pathways for legal implementation. AIFA encompasses three key dimensions: “AI Technology for All”, “AI Justice for All”, and “AI for All ...
Xiao Yang, Sun Xiaoxia
doaj +1 more source
Strani pravni životOn June 11, 2025, Disney and Universal Studios filed a lawsuit against artificial intelligence (hereinafter: AI) company Midjourney for copyright infringement.
Nikola R. Milosavljević
doaj +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Indian Journal of Community MedicineArtificial Intelligence (AI) has revolutionized healthcare by addressing infrastructural inadequacies, doctor shortages, and inaccessibility. Other than enhancing diagnostics, data analysis, trend analysis, and precision medicine, AI has been ...
Najam Khalique +3 more
doaj +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
The New Challenges of Artificial Intelligence in Digital Transformation and Economic Competitiveness [PDF]
Ovidius University Annals: Economic Sciences SeriesThe recent adoption of the European Union Law on Artificial Intelligence (AI) in 2024 has created a regulatory framework that aims to balance innovation and ethical governance for the advancement of AI in the EU.
Nicoleta Sîrghi +1 more
doaj