Results 51 to 60 of about 184,514 (215)
FEBS Open Bio, EarlyView.UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová +2 more
wiley +1 more source
Limitations of risk-based artificial intelligence regulation: a structuration theory approach
Discover Artificial IntelligenceArtificial Intelligence (AI) is transforming the way we live and work. The disruptive impact and risks of Generative AI have accelerated the global transition from voluntary AI ethics guidelines to mandatory AI regulation.
Lily Ballot Jones +2 more
doaj +1 more source
Directed evolution of enzymes at the crossroads of tradition and innovation
FEBS Open Bio, EarlyView.An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
General-purpose AI regulation and the European Union AI Act
Internet Policy ReviewThis article provides an initial analysis of the EU AI Act's (AIA) approach to regulating general-purpose artificial intelligence (AI) – such as OpenAI's ChatGPT – and argues that it marks a significant shift from reactive to proactive AI governance ...
Oskar J. Gstrein +2 more
doaj +1 more source
Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA
FEBS Open Bio, EarlyView.PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro +1 more
wiley +1 more source
Healthcare ethics and artificial intelligence: a UK doctor survey
BMJ OpenObjectives To survey UK doctors on their uses of artificial intelligence (AI) and of their views on the ethics and regulation of AI in healthcare.Design Anonymous cross-sectional e-survey.Setting An online survey of UK General Medical Council (GMC ...
Søren Holm, Daniel Joseph Warrington
doaj +1 more source
How phagocytic cells kill bacteria: Lessons from a professional killer
FEBS Open Bio, EarlyView.How phagocytic cells ingest and kill bacteria has been studied for more than a century, but many questions remain unanswered. The study of the amoeba Dictyostelium discoideum brings new answers, and new questions. Professional phagocytic cells such as neutrophils and macrophages, as well as free‐living soil amoebae like Dictyostelium discoideum, employ
Otmane Lamrabet, Pierre Cosson
wiley +1 more source
Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells
FEBS Open Bio, EarlyView.Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim +4 more
wiley +1 more source
European AI Standards – Technical Standardisation and Implementation Challenges under the EU AI Act
European Journal of Risk RegulationHarmonised standards are the cornerstone of efficient EU AI Act compliance. This paper presents one of the first systematic analyses of European technical and soon to be harmonised standardisation for organisations providing AI systems. Based on in-depth
Robert Kilian, Linda Jäck, Dominik Ebel
doaj +1 more source
Conformity Assessments and Post-market Monitoring: A Guide to the Role of Auditing in the Proposed European AI Regulation. [PDF]
Minds Mach (Dordr), 2022 Mökander J +3 more
europepmc +1 more source