Results 101 to 110 of about 1,438,526 (344)

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Folder 22: AIDS ARMS Network - Newspaper Clippings, Correspondences from lawyers, meetings minutes, correspondence to John Thomas, 1986-1987, 1989-1993

open access: yes, 1990
A receipt of a payment from the AIDS ARMS Network, Inc. (Prism Health North Texas) to the AIDS Resource Center (Resource Center Dallas)
AIDS ARMS Network, Inc.
core   +1 more source

Atendimento psicossocial à Aids

open access: yesDST, 2004
Introdução: tendo como base a necessidade de ampliação de estrutura de suporte psicológico para portadores do HIV-aids, este estudo se justifica pelacomplexidade do atendimento, em que a contrapartida psicossocial da doença exige uma estrutura integrada
Ana A.W. Saldanha   +2 more
doaj  

The prevalence of syphilis in HIV-seropositive patients: a retrospective study at the regional hospital in Agadir, Morocco

open access: yesThe Pan African Medical Journal, 2019
INTRODUCTION: HIV and syphilis are major public health problems in Morocco. The region of Souss-Massa, south-west of the country, hold more than 24% of HIV seropositive cases registered in Morocco during 2009.
Mohamed Bourouache   +9 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Representações sociais de DST/Aids para adolescentes de uma instituição abrigo com experiência pregressa de vida nas ruas da cidade de Goiânia

open access: yesDST, 2004
Introdução: os adolescentes em situação de rua apresentam maior vulnerabilidade às DST/Aids, por conviverem com a violência, tráfico de drogas eexploração sexual inerentes ao universo das ruas e, também devido às dificuldades de assimilação de ...
Ida K. Borges, Marcelo Medeiros
doaj  

Estimating the cost to rural ambulating HIV/AIDS patients on Highly Active Antiretroviral Therapy (HAART) in rural Ghana: a pilot study

open access: yesThe Pan African Medical Journal, 2012
INTRODUCTION: Subsidized antiretroviral therapy programs obviously lowers the cost of antiretroviral drugs but other major costs are still incurred, which makes the overall cost of accessing and consuming antiretroviral treatment very high and sometimes ...
Stephen Apanga   +2 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

A magnitude da infecção pelo HIV-Aids em maiores de 50 anos no Município de Fortaleza-CE

open access: yesDST, 2004
Introdução: atualmente, têm-se percebido mudanças no curso da epidemia da aids, e uma delas é o aumento do número de casos na faixa etária de 50 a 70 anos, o que vem demonstrar a exclusão deste grupo nos projetos e programas de educação e prevenção do ...
Aline R. Feitoza   +2 more
doaj  

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