Results 101 to 110 of about 1,065,261 (297)

Comparação da coleta das amostras de sangue na triagem pré-natal, utilizando o papel de filtro e punção venosa na técnica de ELISA para detecção de HIV 1+2

open access: yesDST, 2010
Introdução: apesar de o papel de filtro (PF) ter sido introduzido desde o século passado, (1963) por Guthrie e Susi, nas triagens neonatais, como alternativa para a coleta da amostra do sangue, seus benefícios na aplicação da prática médica laboratorial
Juan Fidel Bencomo Gómez   +6 more
doaj  

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Vulnerability of adolescents to sexually transmitted infections

open access: yesDST, 2018
Introduction: Adolescents are especially susceptible to sexually transmitted infections, with approximately 1/7 of all new cases of human immunodeficiency virus infection in this group. Objective: To investigate the vulnerability to sexually transmitted
Raisa Evaly Alves de Rezende   +6 more
doaj  

Current Status Towards 90-90-90 UNAIDS Target and Factors Associated with HIV Viral Load Suppression in Kediri City, Indonesia

open access: yesHIV/AIDS: Research and Palliative Care, 2020
Geofrey Ssekalembe, 1 Muhammad Atoillah Isfandiari, 1 Hendick Suprianto 2 1Faculty of Public Health, Universitas Airlangga, Surabaya, Indonesia; 2Dinas Kesehatan Kota Kediri, Kediri, IndonesiaCorrespondence: Geofrey SsekalembeFaculty of Public Health ...
Ssekalembe G, Isfandiari MA, Suprianto H
doaj  

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Series 2: Publications : AIDS Update, 1988-1994

open access: yes, 1990
Monthly newsletter describing news and events related to the AIDS Resource Center in Dallas, Texas as well as articles, letters, advice columns, and advertisements of interest to ...
AIDS Resource Center (Dallas, Tex.)
core   +3 more sources

Diagnóstico diferencial das manifestações da sífilis e da Aids com líquen plano na boca

open access: yesDST, 2012
A sífilis segue um curso semiológico em que aparece, desaparece e ressurge com variados sinais e sintomas, exigindo dos examinadores conhecimentos clínicos e laboratoriais que os conduzam ao seu diagnóstico.
Andrea B. Moleri   +5 more
doaj  

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

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