Results 111 to 120 of about 1,438,526 (344)
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Erotismo e prevenção de DST/Aids entre os adolescentes
Introdução: os meios de comunicação têm tido uma participação cada vez mais frequente e intensa nas pessoas, principalmente nos jovens, mas nãose tem conhecimento de que tipo de informação sobre erotização e prevenção de DST/Aids está sendo passada aos ...
Glauco R Mello +3 more
doaj
Hong Zhang,1,2 Yao Yin,1 Huan Wang,1 Ying Han,3 Xia Wang,1 Yi Liu,4 Hong Chen1 1West China School of Nursing, Sichuan University/West China Hospital, Sichuan University, Chengdu, Sichuan Province, People’s Republic of China; 2Department of Nursing ...
Zhang H +6 more
doaj
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Toksoplasmosis Serebral Pada Pasien dengan HIV/AIDS: Laporan Kasus
Background: Toxoplasma encephalitis (ET) is the most common opportunistic infection that causes encephalitis or focal cerebral lesions in HIV/AIDS sufferers which occurs in approximately 3% to 40% of patients.
Gede Ari Mahendra Mardaningrat +2 more
doaj +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Introdução: apesar de o papel de filtro (PF) ter sido introduzido desde o século passado, (1963) por Guthrie e Susi, nas triagens neonatais, como alternativa para a coleta da amostra do sangue, seus benefícios na aplicação da prática médica laboratorial
Juan Fidel Bencomo Gómez +6 more
doaj
Decision aids for people facing health treatment or screening decisions.
D. Stacey +11 more
semanticscholar +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source

