Results 131 to 140 of about 1,065,261 (297)

Series 2: Publications : AIDS Update, 1988-1994

open access: yes, 1991
Monthly newsletter describing news and events related to the AIDS Resource Center in Dallas, Texas as well as articles, letters, advice columns, and advertisements of interest to ...
AIDS Resource Center (Dallas, Tex.)
core   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Folder 22: AIDS ARMS Network - Newspaper Clippings, Correspondences from lawyers, meetings minutes, correspondence to John Thomas, 1986-1987, 1989-1993

open access: yes, 1987
A set of statistics about patients with AIDS who had requested assistance from the AIDS ARMS Network as of February 23 ...
AIDS ARMS Network, Inc.
core  

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Editorial Letter” HIV-related Stigma: A Dilemma in the Prevention of HIV Spread

open access: yesنشریه پرستاری ایران, 2018
HIV/AIDS is a global health concern that spans three decades of its emergence(1). However, it remains a complex, unique issue among experts. While HIV/AIDS is medically recognized as a chronic, fatal disease, there is a social stigma attached to the ...
M Gharacheh, F Ranjbar
doaj  

Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers

open access: yesFEBS Letters, EarlyView.
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui   +4 more
wiley   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

open access: yesFEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil   +3 more
wiley   +1 more source

Rencana Aksi Nasional Penanggulangan HIV dan AIDS di Indonesia 2007-2010

open access: yes, 2007
Buku ini berisi Rencana Aksi Nasional (RAN) Penaggulangan AIDS di Indonesia Tahun 2007-2010, yang terdiri atas latar belakang dan justifikasi, program penanggulangan AIDS, kebutuhan sumber daya dan strategi mobilisasi sumber daya, serta dukungan ...
Komisi Penanggulangan AIDS
core  

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