Results 211 to 220 of about 1,065,261 (297)

Barriers to Treatment Resulting in Multiple Coexisting Infections and Hospice in a Young Person With Acquired Immunodeficiency Syndrome (AIDS). [PDF]

Cureus
Bartholomew A, Calico M, Macaulay J, Loehr C, Sanne S.   +4 more
europepmc   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source

Shared decision making in pain care: a systematic review study protocol of decision aids. [PDF]

BMJ Open
Hess CW, McDonnell A, Sahaym O, Masood S, Davis A, Smyth H, Nguyen H, Wong C, Lipstein EA, Zisman-Ilani Y, Simons L.   +10 more
europepmc   +1 more source

Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk

Molecular Oncology, EarlyView.
Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley   +1 more source

AIDS and aid.

CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2002
openaire   +1 more source

Longitudinal national surveys reflect steady challenges for AIDS drug assistance programs, 2017-2024. [PDF]

Front Public Health
Rogers EQ, Killelea A, Horn T, Panagides R, Keim-Malpass J, Liu F, Steen A, McManus KA.   +7 more
europepmc   +1 more source

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

Molecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

Epidemiological Trends, Transmission Dynamics, and Mortality Patterns of HIV/AIDS in South Korea, 1985-2024: A Comprehensive Regression and Time Series Analysis with Projections to 2028. [PDF]

Viruses
Jung H, Jung M.
europepmc   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

Distribution of HIV-1 subtypes and molecular transmission networks among HIV/AIDS cases in Dinghai District, Zhoushan, China. [PDF]

Medicine (Baltimore)
Wang Y, Zhang B, Gu S, Yu Q, Chen J.
europepmc   +1 more source