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The AIDS dementia complex: II. Neuropathology

open access: yesAnnals of Neurology, 1986
AbstractIn order to define the histopathological substrate of the dementia that frequently complicates the acquired immune deficiency syndrome (AIDS), we analyzed the neuropathological findings in 70 autopsied adult AIDS patients, 46 of whom had suffered clinically overt dementia. Less than 10% of the brains were histologically normal.
B. Navia, E. Cho, C. Petito, R. W. Price
semanticscholar   +4 more sources
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AIDS Dementia Complex: Neurotoxicity in AIDS Patients.

Critical Reviews in Eukaryotic Gene Expression, 2023
AIDS dementia complex (ADC) is a nervous system disorder that harms the neurons in different parts of the brain. Various features are involved in altering the normal activities of neurons. Neurotoxicity is induced due to HIV viral proteins such as gp120,
M. Qadir, Bilal Ahmed, Sumaira Noreen
semanticscholar   +3 more sources

Cerebrospinal fluid cytokines in AIDS dementia complex

Journal of Neurology, 1992
We evaluated cerebrospinal fluid (CSF) and serum concentrations of interleukin-1-alpha (IL-1-alpha), interleukin-6 (IL-6) and tumour necrosis factor-alpha (TNF-alpha) in 30 patients with AIDS dementia complex (ADC), and in 20 HIV-seronegative subjects with other neurological diseases (OND).
O. Perrella   +3 more
exaly   +5 more sources

The AIDS dementia complex.

Journal of Infectious Diseases, 1988
Note from Dr. Merle A. Sande?Progressive dementia has been recognized as a complication of human immunodeficiency virus infection almost since the beginning of the epidemic. To many infectious diseases clinicians, however, the AIDS dementia complex remains ambiguous, and the clinical approach to this problem is less clearly defined than that for other ...
R. Price, B. Brew
semanticscholar   +3 more sources

The metabolic pathology of the AIDS dementia complex

Annals of Neurology, 1987
AbstractA progressive dementing illness, the AIDS dementia complex (ADC) is the most frequent neurological complication of the acquired immunodeficiency syndrome. Characteristic alterations in regional cerebral metabolic rate for glucose (rCMRGlc), associated with the presence or progression of ADC, were demonstrated by {18F} fluorodeoxy glucose ...
D. Rottenberg   +7 more
semanticscholar   +3 more sources

AIDS dementia complex in China

Journal of Clinical Neuroscience, 2007
The AIDS dementia complex (ADC) is one of the most common neurological complications in patients with AIDS. However, little is known about the clinical features of ADC in China. We prospectively studied six patients with confirmed ADC out of a total of 36 AIDS patients treated from 1999 to 2003.
Justin McArthur, Yun-Cheng Wu
exaly   +3 more sources

The AIDS dementia complex: I. Clinical features

Annals of Neurology, 1986
AbstractOf 70 autopsied patients with the acquired immune deficiency syndrome (AIDS), 46 suffered progressive dementia that was frequently accompanied by motor and behavioral dysfunction. Impaired memory and concentration with psychomotor slowing represented the most common early presentation of this disorder, but in nearly one half of the patients ...
B. Navia, B. Jordan, Richard W. Price
semanticscholar   +3 more sources

Neuropsychological characterization of the AIDS dementia complex: a preliminary report.

AIDS, 1988
The AIDS dementia complex (ADC) is a frequent complication of advanced HIV infection. In order to better define the neuropsychological character and progression of the ADC, four groups of subjects were studied with a battery of neuropsychological tests: an HIV-seronegative comparison group (n = 20), asymptomatic HIV-seropositive patients (n = 16 ...
Susan Tross   +6 more
semanticscholar   +3 more sources

AIDS-Dementia Complex: Implications for Practice

open access: yesSocial Casework, 1988
AIDS and the dementia associated with it have created new challenges for social workers. The authors identify unique issues around the AIDS-dementia complex. Implications for social work practice are discussed, and recommendations for assisting the growing population with this complex are made.
Stephan L. Buckingham   +1 more
openaire   +2 more sources

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