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Involvement of quinolinic acid in aids dementia complex
Neurotoxicity Research, 2009Human immunodeficiency virus (HIV) infection is often complicated by the development of acquired immunodeficiency syndrome (AIDS) dementia complex (ADC). Quinolinic acid (QUIN) is an end product of tryptophan, metabolized through the kynurenine pathway (KP) that can act as an endogenous brain excitotoxin when produced and released by activated ...
G. Guillemin, S. Kerr, B. Brew
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The aids dementia complex: Some current questions
Annals of Neurology, 1988The acquired immunodeficiency syndrome (AIDS) dementia complex (ADC) commonly complicates the course of human immunodeficiency virus (HIV) infection and AIDS. Although many of its clinical aspects have recently been brought into clearer focus, and pathogenetic evidence has accrued implicating direct HIV brain infection, there remain a number of ...
R. W. Price, J. Sidtis, M. Rosenblum
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The acquired immunodeficiency syndrome (AIDS) dementia complex.
Annals of Internal Medicine, 1989The acquired immunodeficiency syndrome (AIDS) dementia complex is a frequent and devastating complication of infection with human immunodeficiency virus-type 1 (HIV-1). Features of the AIDS dementia complex include decreased memory, the inability to concentrate, apathy, and psychomotor retardation.
David D. Ho +3 more
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Involvement of dopamine in the progression of AIDS Dementia Complex
Journal of Neural Transmission, 2002HIV compromises immunological functions. Immune responses are regulated to a great extent by several molecules such as cytokines, neurotransmitters and hormones which interact with different immune effector cells and ultimately mediate the homeostatic responses to disease. Among these mediators, dopamine plays an important role.
E. Koutsilieri +4 more
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Astrocytes and the AIDS Dementia Complex
Journal of Neuro-AIDS, 1995Dale J Benos, E N Benveniste
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AIDS Patient Care, 1989
A common complication of acquired immunodeficiency syndrome (AIDS) is being increasingly recognized. Known as AIDS dementia complex, the disorder is characterized by global impairment of intellectual and cognitive functions, personality and behavioral disturbances, and motor dysfunction manifested by impaired speech, gait, and coordination.
L A, Weisberg, W, Ross
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A common complication of acquired immunodeficiency syndrome (AIDS) is being increasingly recognized. Known as AIDS dementia complex, the disorder is characterized by global impairment of intellectual and cognitive functions, personality and behavioral disturbances, and motor dysfunction manifested by impaired speech, gait, and coordination.
L A, Weisberg, W, Ross
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Journal of Neuropathology and Experimental Neurology, 2003
Constantin Yiannoutsos +2 more
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Constantin Yiannoutsos +2 more
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CNS Drugs, 1998
In the advanced stages of HIV infection, 15 to 20% of patients develop a progressive encephalopathy that has been termed ‘AIDS dementia complex’ (ADC) or ‘HIV dementia’. Clinically, this is a subcortical dementia that is characterised by slow mental functioning.
Peter Portegies, Nathalie R. Rosenberg
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In the advanced stages of HIV infection, 15 to 20% of patients develop a progressive encephalopathy that has been termed ‘AIDS dementia complex’ (ADC) or ‘HIV dementia’. Clinically, this is a subcortical dementia that is characterised by slow mental functioning.
Peter Portegies, Nathalie R. Rosenberg
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Adjunctive therapies for AIDS dementia complex
Cochrane Database of Systematic Reviews, 2008AIDS dementia complex is a common complication of human immunodeficiency virus type 1 (HIV-1) that continues to exist despite the current use of potent antiretroviral therapy. It is a source of great morbidity and, when severe, is associated with limited survival.To determine efficacy and safety of adjunctive therapies for AIDS dementia complexWe ...
Olalekan A, Uthman, Jubril O, Abdulmalik
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