Results 131 to 140 of about 22,661 (290)

Viral modulation of interferon (IFN) responses to african swine fever virus (ASFV) [PDF]

, 2011
Tese de mestrado. Biologia (Biologia Humana e Ambiente). Universidade de Lisboa, Faculdade de Ciências, 2011A imunidade inata constitui a primeira resposta dada por um hospedeiro quando atacado por agentes patogénicos. A resposta imune baseia-se em genes
Costa, Emanuel Nery de Oliveira Quartin, 1986-
core  

On some non-conformal fractals

, 2010
This paper presents a simple method of calculating the Hausdorff dimension for a class of non-conformal ...
Gui Y, Gui Y, Luzia N, Michał Rams, Nielsen O A, Reeve H   +5 more
core   +1 more source

Structural Basis for the Recognition in an Idiotype-Anti-Idiotype Antibody Complex Related to Celiac Disease [PDF]

, 2014
Anti-idiotype antibodies have potential therapeutic applications in many fields, including autoimmune diseases. Herein we report the isolation and characterization of AIM2, an anti-idiotype antibody elicited in a mouse model upon expression of the celiac
Abdel-Azeim, Safwat, Caputo, Ivana, Cavallo, Luigi, Di Niro, Roberto, Oliva, Romina, Sblattero, Daniele, Vangone, Anna   +6 more
core   +4 more sources

Macrophage IL-1β contributes to tumorigenesis through paracrine AIM2 inflammasome activation in the tumor microenvironment [PDF]

, 2023
Zhi Huan Chew, Jianzhou Cui, Karishma Sachaphibulkij, Isabelle Tan, Shreya Kar, Kai Kiat Koh, Kritika Singh, Hong Meng Lim, Soo Chin Lee, Alan Prem Kumar, Stephan Gasser, Lina H. K. Lim   +11 more
openalex   +1 more source

AIM2 Blocks Colon Cancer in Three Ways [PDF]

Cancer Discovery, 2015
Abstract Known for its antipathogenic role, the inflammasome protein AIM2 also helps prevent tumors. One new study suggests that the protein's tumor suppressor activity stems from its ability to inhibit AKT. A second study indicates that the protein curtails proliferation of intestinal stem cells and controls the composition of the ...
openaire   +1 more source

Immunology in clinic review series; focus on autoinflammatory diseases: role of inflammasomes in autoinflammatory syndromes [PDF]

, 2012
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/90366/1/j.1365-2249.2011.04535.x ...
Franchi, Luigi, Ozkurede, V. U.
core   +1 more source

A High-Protein Diet Promotes Atrial Arrhythmogenesis via Absent-in-Melanoma 2 Inflammasome

Cells
High-protein diets (HPDs) offer health benefits, such as weight management and improved metabolic profiles. The effects of HPD on cardiac arrhythmogenesis remain unclear.
Jia Song, Jiao Wu, Dexter J. Robichaux, Tingting Li, Shuyue Wang, Maria J. Arredondo Sancristobal, Bingning Dong, Dobromir Dobrev, Jason Karch, Sandhya S. Thomas, Na Li   +10 more
doaj   +1 more source

The DNA Sensor AIM2 Maintains Intestinal Homeostasis via Regulation of Epithelial Antimicrobial Host Defense

Cell Reports, 2015
Microbial pattern molecules in the intestine play immunoregulatory roles via diverse pattern recognition receptors. However, the role of the cytosolic DNA sensor AIM2 in the maintenance of intestinal homeostasis is unknown.
Shuiqing Hu, Lan Peng, Youn-Tae Kwak, Erin McElvania Tekippe, Chandrashekhar Pasare, James S. Malter, Lora V. Hooper, Md. Hasan Zaki   +7 more
doaj   +1 more source

AIM2 exacerbates hypoxic-ischemic brain damage in neonatal rats via promoting neuronal pyroptosis

Brain Research Bulletin
Background: Pyroptosis has been reported to play a pathogenic role in neonatal hypoxic-ischemic brain damage (HIBD). Absence in melanoma 2 (AIM2) is an inflammasome involved in pyroptosis.
Qianqian Li, Zengqin Wang, Fengli Li, Songlin Liu, Yuhong Ding, Junmei Yan, Xing Feng, Mei Li   +7 more
doaj   +1 more source

AIM2 Mediates Inflammation-Associated Renal Damage in Hepatitis B Virus-Associated Glomerulonephritis by Regulating Caspase-1, IL-1β, and IL-18

Mediators of Inflammation, 2014
Background & Aims. AIM2 plays an important role in innate immunity, but its role in regulating the immune response to hepatitis B virus (HBV) is unknown.
Junhui Zhen, Le Zhang, Jiachao Pan, Shumin Ma, Xiaojian Yu, Xiaobo Li, Shijun Chen, Wenjun Du   +7 more
doaj   +1 more source