Results 61 to 70 of about 565,432 (329)
Energies, 2022 The utilization of condensate water as a compressor-discharge cooler results in subcooling on the condenser outlet. On the other hand, a split-type air conditioner (A/C) with R32 as working fluid can provide higher compressor-discharge temperatures than ...
Kasni Sumeru +5 more
doaj +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Applicability of energy consumption prediction models in a department store: A case study
Case Studies in Thermal Engineering, 2023 Obtaining an accurate picture of energy consumption in public spaces is a critical first step for predicting and enhancing energy efficiency. In practice, such calculations are often complicated, necessitating use of artificial intelligence models which ...
Li-Yuan Chen +3 more
doaj +1 more source
Buildings for low energy air conditioning [PDF]
, 1998 Over half of global warming is thought to be attributable to the burning of fossil fuelsand slightly less than half of this is due to conditioning the environment withinbuildings.
Oreszczyn, T
core
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
UK domestic air conditioning: a study of occupant use and energy efficiency [PDF]
, 2008 This paper presents the results of a study of air-conditioning usage in homes in the southeast of England. First part of the study consisted surveying 13 dwellings with air-conditioning for a series of 4 week periods during the summer of 2004.
Oreszczyn, T., Pathan, A., Young, A.
core
Quality control improvement at Jana DCS Sdn. Bhd. [PDF]
, 2020 Jana DCS Sdn. Bhd. is one of the companies that run the service of air conditioning system supply in Nusajaya, Johor, Malaysia. Quality improvement is one of the most important part when talking about a company, mostly companies that operate in service ...
Abd Wahab, Muhammad Badrul Amin +4 more
core
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Prospects of the hydraulic air conditioning of mold air on the basis of pulse wave effects [PDF]
, 2019 The results of analytical and technical substantiation of promising solutions for the development of tools for hydraulic conditioning of mine air in deep mine conditions that combine cooling and purification of air based on pulse-wave effects ...
Gogo, V. B. +3 more
core +1 more source