Results 61 to 70 of about 1,100,520 (348)

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Traffic-related air pollution near roadways: discerning local impacts from background [PDF]

Atmospheric Measurement Techniques, 2019
Adverse health outcomes related to exposure to air pollution have gained much attention in recent years, with a particular emphasis on traffic-related pollutants near roadways, where concentrations tend to be most severe.
N. Hilker, J. M. Wang, C.-H. Jeong, R. M. Healy, U. Sofowote, J. Debosz, Y. Su, M. Noble, A. Munoz, G. Doerksen, L. White, C. Audette, D. Herod, J. R. Brook, J. R. Brook, G. J. Evans   +15 more
doaj   +1 more source

Global anthropogenic emissions (CAMS-GLOB-ANT) for the Copernicus Atmosphere Monitoring Service simulations of air quality forecasts and reanalyses

Earth System Science Data
. Anthropogenic emissions are the result of many different economic sectors, including transportation, power generation, industrial, residential and commercial activities, waste treatment and agricultural practices.
A. Soulié, C. Granier, S. Darras, Nicolas Zilbermann, T. Doumbia, M. Guevara, J. Jalkanen, S. Keita, C. Liousse, Monica Crippa, D. Guizzardi, R. Hoesly, Steven J. Smith   +12 more
semanticscholar   +1 more source

Towards sustainable and net-zero cities: A review of environmental modelling and monitoring tools for optimizing emissions reduction strategies for improved air quality in urban areas.

Environmental Research, 2023
Climate change is a defining challenge for today's society and its consequences pose a great threat to humanity. Cities are major contributors to climate change, accounting for over 70% of global greenhouse gas emissions. With urbanization occurring at a
A. C. O'Regan, M. Nyhan
semanticscholar   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Extending BIM for Air Quality Monitoring

, 2020
Opis vira z dne 24. 4. 2021.
Mrissa, Michael Nicolas, Vcelak, Jan, Hajdu, László, Dávid, Balázs, Krész, Miklós Ferenz, Sandak, Jakub Michal, Sandak, Anna Malgorzata, Kanduti, Rok, Varkonji, Monika, Jutraž, Anja, Malovrh Rebec, Katja   +10 more
openaire   +5 more sources

Health impact of China's Air Pollution Prevention and Control Action Plan: an analysis of national air quality monitoring and mortality data.

Lancet Planetary Health, 2018
BACKGROUND To mitigate the serious levels of air pollution in China, the State Council of China issued the Air Pollution Prevention and Control Action Plan (APPCAP) in 2013. This policy is a milestone in air quality control in China. We aimed to evaluate
Jing Huang, X. Pan, Xinbiao Guo, Guoxing Li   +3 more
semanticscholar   +1 more source

A Q-learning-based routing scheme for smart air quality monitoring system using flying ad hoc networks

Scientific Reports, 2022
Air pollution has changed ecosystem and atmosphere. It is dangerous for environment, human health, and other living creatures. This contamination is due to various industrial and chemical pollutants, which reduce air, water, and soil quality.
J. Lánský, A. Rahmani, S. M. Zandavi, Vera Chung, Efat Yousefpoor, Mohammad Sadegh Yousefpoor, Faheem Khan, M. Hosseinzadeh   +7 more
semanticscholar   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Complexities of peroxyacetyl nitrate photochemistry and its control strategies in contrasting environments in the Pearl River Delta region

npj Climate and Atmospheric Science
Peroxyacetyl nitrate (PAN) is a hazardous secondary pollutant and a nitrogen reservoir in the troposphere, while comprehensive studies on its spatiotemporal distribution, chemical sources, and control strategies are limited.
Tao Liu, Yu Wang, Huang Cai, Hao Wang, Chunlin Zhang, Jun Chen, Yan Dai, Wenlong Zhao, Jiangyong Li, Daocheng Gong, Duohong Chen, Yuhong Zhai, Yan Zhou, Tong Liao, Boguang Wang   +14 more
doaj   +1 more source