Results 61 to 70 of about 1,613,595 (364)

TRPM4 contributes to cell death in prostate cancer tumor spheroids, and to extravasation and metastasis in a zebrafish xenograft model system

Molecular Oncology, EarlyView.
Transient receptor potential melastatin‐4 (TRPM4) is overexpressed in prostate cancer (PCa). Knockout of TRPM4 resulted in reduced PCa tumor spheroid size and decreased PCa tumor spheroid outgrowth. In addition, lack of TRPM4 increased cell death in PCa tumor spheroids.
Florian Bochen, Saurav Subedi, Federico La Manna, Sofia Jarrin, Irida Papapostolou, Marianna Kruithof‐de Julio, Christine Peinelt   +6 more
wiley   +1 more source

Research on Mobile Network Parameters Using Unmanned Aerial Vehicles

Sensors
The study of phenomena related to the propagation of electromagnetic waves is a necessity with the development of mobile telephony networks. This paper deals with the problem of the quality of mobile telephony signals.
Jan Warczek, Jarosław Kozuba, Marek Marcisz, Wiesław Pamuła, Krzysztof Dyl   +4 more
doaj   +1 more source

Electronic Transport Properties of Pentacene Single Crystals upon Exposure to Air [PDF]

, 2005
We report the effect of air exposure on the electronic properties of pentacene single crystals. Air can diffuse reversibly in and out of the crystals and controls the physical properties. We discern two competing mechanisms that modulate the electronic transport.
arxiv   +1 more source

MET variants with activating N‐lobe mutations identified in hereditary papillary renal cell carcinomas still require ligand stimulation

Molecular Oncology, EarlyView.
MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin, Audrey Vinchent, Marie Fernandes, Isabelle Damour, Agathe Laratte, Rémi Tellier, Gabriella O. Estevam, Jean‐Pascal Meneboo, Céline Villenet, Clotilde Descarpentries, James S. Fraser, Martin Figeac, Alexis B. Cortot, Etienne Rouleau, David Tulasne   +14 more
wiley   +1 more source

Infrastructure, Competition Regimes and Air Transport Costs: Cross Country Evidence [PDF]

The relevance of transport costs has increased as liberalization continues to reduce artificial barriers to trade. Countries need to adopt policies to “get closer†to global markets.
Alejandro Micco, Tomás Serebrisky
core   +6 more sources

On the use of fuzzy neural networks in the framework of a risk-based approach in control and supervisory activities in civil aviation

Научный вестник МГТУ ГА, 2023
A risk-oriented approach implemented in conducting control and supervisory activities in Civil Aviation organizations makes it possible to increase the effectiveness of such activities, the objectivity of assessments, to reduce costs and the ...
R. А. Obraztsov, V. D. Sharov
doaj   +1 more source

Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression

Molecular Oncology, EarlyView.
Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park, Jae Won Oh, Hyewon Chung, Jung Won Kwon, Yi Rang Na, Kwang Pyo Kim, Seung Hyeok Seok   +6 more
wiley   +1 more source

Interdependent Uncertainty Handling in Trajectory Prediction

Aerospace, 2019
The concept of 4D trajectory management relies on the prediction of aircraft trajectories in time and space. Due to changes in atmospheric conditions and complexity of the air traffic itself, the reliable prediction of system states is an ongoing ...
Thomas Zeh, Judith Rosenow, Hartmut Fricke   +2 more
doaj   +1 more source

Passenger-Centric Urban Air Mobility: Fairness Trade-Offs and Operational Efficiency [PDF]

Transportation Research Part C: Emerging Technologies. Volume 136, March 2022, 103519, 2021
Urban Air Mobility (UAM) has the potential to revolutionize transportation. It will exploit the third dimension to help smooth ground traffic in densely populated areas. To be successful, it will require an integrated approach able to balance efficiency and safety while harnessing common resources and information.
arxiv  

Germline variants in CDKN2A wild‐type melanoma prone families

Molecular Oncology, EarlyView.
Among melanoma‐prone families, wild‐type for CDKN2A and CDK4, some have pathogenic variants in genes not usually linked to melanoma. Furthermore, rare XP‐related variants and variants in MC1R are enriched in such families. Germline pathogenic variants in CDKN2A are well established as an underlying cause of familial malignant melanoma. While pathogenic
Gjertrud T. Iversen, Marie Loeng, Amalie Lund Holth, Per E. Lønning, Jürgen Geisler, Stian Knappskog   +5 more
wiley   +1 more source