Results 61 to 70 of about 1,030,202 (307)

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Servo-Elastic Control of a Flexible Airship with Multiple Vectored Propellers

Aerospace
Owing to its large flexible envelope, an airship is highly sensitive to environmental disturbances, such as wind gusts. Fluid–structure interaction induces structural deformation, which modifies the aerodynamic force distribution and introduces ...
Li Chen, Lewei Huang, Jie Lin
doaj   +1 more source

Pioglitazone plus (−)‐epigallocatechin gallate: a novel approach to enhance osteogenic performance in aged bone marrow mesenchymal stem cells

FEBS Open Bio, EarlyView.
Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen, Jia‐Ci Jhang, Chun‐Yi Peng, Quốc Cường Nguyễn, Feng‐Huei Lin, Hung‐Ming Wu, Shankung Lin   +6 more
wiley   +1 more source

Life prediction and health assessment of aero-engine gas path using digital twin and deep learning

Complex & Intelligent Systems
This study proposes a system for health monitoring and remaining useful life (RUL) prediction of aviation engine gas path that integrates digital twins and deep learning.
Mingyue Wu, Hong Zhou, Rao Yao, Shuhong Ren   +3 more
doaj   +1 more source

Study on Spatial-Temporal Evolution, Decoupling Effect and Influencing Factors of Tourism Transportation Carbon Emissions: Taking North China as an Example

Atmosphere
As global warming intensifies, reducing carbon emissions has become a global common mission. Tourism transportation is one of the important sources of carbon emissions, and reducing its carbon emissions is a key part of achieving China’s carbon reduction
Dongni Feng, Cheng Li, Yangzhou Li
doaj   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

FEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold, Janik Riese, Lancelot Seillier, Mark Kühnel, Julia Pannhausen, Charlotte O. J. Fröhlich, Christian Martin, Peter Boor, Matthias Saar, Danny D. Jonigk, Nadine T. Gaisa, Michael Rose   +11 more
wiley   +1 more source

Survey of projected growth and problems facing air transportation, 1975 - 1985 [PDF]

Results are presented of a survey conducted to determine the current opinion of people working in air transportation demand forecasting on the future of air transportation over the next ten years.
Williams, L. J., Wilson, A.
core   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

FEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi, Zainab Quraishi, Shima Khezri Azizi Far, Madaleine Ward, Aidan Conway, Reem Abdulredha, Eman Mshari, Yousif A. Shamsaldeen   +7 more
wiley   +1 more source

A Collaborative Route Optimization Model for Regional Multi-Airport System

IEEE Access, 2019
In this paper, the author set up an index system on the airport collaboration of the multi-airport system (MAS), including the number of external routes, the total cost of the route network, the passenger volume of the MAS, the airport primacy ratio, the
Li Zhang, Cheng Li, Kai Xu, Yiqin Yang
doaj   +1 more source