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A new role for exhaled nitric oxide as a functional marker of peripheral airway caliber changes: a theoretical study [PDF]

arXiv, 2017
Though considered as an inflammation marker, exhaled nitric oxide (FENO) was shown to be sensitive to airway caliber changes to such an extent that it might be considered as a marker of them. It is thus important to understand how these changes and their localization mechanically affect the total NO flux penetrating the airway lumen (JawNO), hence FENO,
Haut, Benoît, Karamaoun, Cyril, Van Muylem, Alain   +2 more
arxiv   +3 more sources

CCL4 Affects Eosinophil Survival via the Shedding of the MUC1 N-Terminal Domain in Airway Inflammation. [PDF]

Cells
Eosinophilic chronic rhinosinusitis (ECRS), a CRS with nasal polyps (CRSwNP), is characterized by eosinophilic infiltration with type 2 inflammation and is highly associated with bronchial asthma.
Kobayashi Y, Hanh CH, Yagi N, Le NKT, Yun Y, Shimamura A, Fukui K, Mitani A, Suzuki K, Kanda A, Iwai H.   +10 more
europepmc   +2 more sources

Airways [PDF]

BMJ, 1963
E. Thomas
openalex   +3 more sources

IL-17A produced by αβ T cells drives airway hyper-responsiveness in mice and enhances mouse and human airway smooth muscle contraction [PDF]

Nature Medicine, 2012
Emerging evidence suggests that the T helper 17 (T(H)17) subset of αβ T cells contributes to the development of allergic asthma. In this study, we found that mice lacking the αvβ8 integrin on dendritic cells did not generate T(H)17 cells in the lung and ...
Xin Ren, Kamran Atabai, Xiaozhu Huang
exaly   +3 more sources

The Neutralization of the Eosinophil Peroxidase Antibody Accelerates Eosinophilic Mucin Decomposition

Cells, 2023
Eosinophilic airway inflammation, complicated by bronchial asthma and eosinophilic chronic rhinosinusitis (ECRS), is difficult to treat. The disease may become refractory when eosinophilic mucin associated with eosinophil peroxidase (EPX) and ...
Yoshiki Kobayashi, Hanh Hong Chu, Dan Van Bui, Yasutaka Yun, Linh Manh Nguyen, Akitoshi Mitani, Kensuke Suzuki, Mikiya Asako, Akira Kanda, Hiroshi Iwai   +9 more
doaj   +1 more source

SARS-CoV2 in public spaces in West London, UK during COVID-19 pandemic

BMJ Open Respiratory Research, 2023
Background Spread of SARS-CoV2 by aerosol is considered an important mode of transmission over distances >2 m, particularly indoors.Objectives We determined whether SARS-CoV2 could be detected in the air of enclosed/semi-enclosed public spaces.Methods
Prashant Kumar, Kian Fan Chung, Ian Adcock, Pankaj K Bhavsar, Hisham Abubakar-Waziri, Gopinath Kalaiarasan, Rebecca Wawman, Faye Hobbs, Claire Dilliway, Fangxin Fang, Christopher Pain, Alexandra Porter, Emma Ransome, Vincent Savolainen   +13 more
doaj   +1 more source

Limb Muscle Reinnervation with the Nerve-Muscle-Endplate Grafting Technique: An Anatomical Feasibility Study

Neurology Research International, 2021
Background. Peroneal nerve injuries results in tibialis anterior (TA) muscle paralysis. TA paralysis could cause “foot drop,” a disabling condition that can make walking difficult.
Liancai Mu, Jingming Chen, Jing Li, Stanislaw Sobotka, Themba Nyirenda   +4 more
doaj   +1 more source

CCL4 Functions as a Biomarker of Type 2 Airway Inflammation

Biomedicines, 2022
Eosinophilic airway inflammatory disease is associated with bronchial asthma, with eosinophilic chronic rhinosinusitis (ECRS) typical of refractory type 2 airway inflammation.
Yoshiki Kobayashi, Hanh Hong Chu, Akira Kanda, Yasutaka Yun, Masami Shimono, Linh Manh Nguyen, Akitoshi Mitani, Kensuke Suzuki, Mikiya Asako, Hiroshi Iwai   +9 more
doaj   +1 more source

Airway compromising an airway [PDF]

BMJ Case Reports, 2016
There are several tracheostomy tube types that can be used by patients who present to the emergency department with temporary or long-term artificial airways. While specific knowledge of each type may not be required, it is important for the emergency physician to be aware of their general structure and the complications that can arise from them ...
Neil Foden, Richard Oakley, Andrew Wesley Hoey   +2 more
openaire   +3 more sources

Human Neutrophil Elastase Degrades SPLUNC1 and Impairs Airway Epithelial Defense against Bacteria [PDF]

, 2013
Background:Acute exacerbations of chronic obstructive pulmonary disease (AECOPD) are a significant cause of mortality of COPD patients, and pose a huge burden on healthcare. One of the major causes of AECOPD is airway bacterial (e.g.
Bowler, RP, Chu, HW, Jiang, D, Schnell, C, Wenzel, SE, Wu, Q   +5 more
core   +12 more sources