Results 91 to 100 of about 773,643 (383)
Coarse-to-fine Airway Segmentation Using Multi information Fusion Network and CNN-based Region Growing [PDF]
arXiv, 2021 Automatic airway segmentation from chest computed tomography (CT) scans plays an important role in pulmonary disease diagnosis and computer-assisted therapy. However, low contrast at peripheral branches and complex tree-like structures remain as two mainly challenges for airway segmentation.
arxiv
Generative-based Airway and Vessel Morphology Quantification on Chest CT Images [PDF]
, 2020 Accurately and precisely characterizing the morphology of small pulmonary structures from Computed Tomography (CT) images, such as airways and vessels, is becoming of great importance for diagnosis of pulmonary diseases. The smaller conducting airways are the major site of increased airflow resistance in chronic obstructive pulmonary disease (COPD ...
arxiv +1 more source
Eosinophilic airway inflammation: role in asthma and chronic obstructive pulmonary disease
Therapeutic Advances in Chronic Disease, 2016 The chronic lung diseases, asthma and chronic obstructive pulmonary disease (COPD), are common affecting over 500 million people worldwide and causing substantial morbidity and mortality.
L. George, C. Brightling
semanticscholar +1 more source
AAVR Expression is Essential for AAV Vector Transduction in Sensory Hair Cells
Advanced Science, EarlyView.Decreased sensitivity to AAV vector transduction in the outer hair cells (OHCs) of adult mice is primarily attributed to reduction of AAVR (Kiaa0319l; Au040320). Knockout of AAVR reduces AAV vector transduction efficiency in both inner hair cells (IHCs) and OHCs in neonatal mice.
Fan Wu +8 more
wiley +1 more source
Cadmium in tobacco smokers: a neglected link to lung disease?
European Respiratory Review, 2018 Cadmium in tobacco smoke may contribute to the development of pulmonary emphysema. However, there is poor understanding of the mechanisms behind the pathogenic role of cadmium in this and other smoking-related lung diseases.
Koustav Ganguly +4 more
doaj +1 more source
NaviAirway: a Bronchiole-sensitive Deep Learning-based Airway Segmentation Pipeline [PDF]
arXiv, 2022 Airway segmentation is essential for chest CT image analysis. Different from natural image segmentation, which pursues high pixel-wise accuracy, airway segmentation focuses on topology. The task is challenging not only because of its complex tree-like structure but also the severe pixel imbalance among airway branches of different generations.
arxiv
Airway acidification initiates host defense abnormalities in cystic fibrosis mice
Science, 2016 Airway infections put to an acid test Most people with cystic fibrosis suffer from chronic respiratory infections. The mechanistic link between this symptom and the genetic cause of the disease (mutations that compromise the function of the cystic ...
Viral S. Shah +16 more
semanticscholar +1 more source
Advanced Science, EarlyView.This study investigates the role of protein arginine methyltransferase 1 (PRMT1) in endothelial cells (ECs) in chronic obstructive pulmonary disease (COPD). Mice with endothelial‐specific PRMT1 deletion develop pulmonary hemorrhage, inflammation, and apoptosis, driven by excessive nuclear factor kappa B activation.
Thi Thuy Vy Tran +7 more
wiley +1 more source
Computational Analysis of Inspiratory and Expiratory Flow in the Lung Airway [PDF]
3rd Thermal and Fluids Engineering Conference (TFEC), 2018, 2018 Inspiratory and expiratory flow in a multi-generation pig lung airway was numerically studied at a peak tracheal flow rate corresponding to a Reynolds number of 1150. The model was validated by comparing velocity distributions with previous measurements for a simple airway bifurcation.
arxiv
Basal cells as stem cells of the mouse trachea and human airway epithelium
Proceedings of the National Academy of Sciences of the United States of America, 2009 The pseudostratified epithelium of the mouse trachea and human airways contains a population of basal cells expressing Trp-63 (p63) and cytokeratins 5 (Krt5) and Krt14.
J. Rock +7 more
semanticscholar +1 more source