Results 91 to 100 of about 783,276 (359)
Adherence to continuous positive airway pressure therapy: the challenge to effective treatment.
Proceedings of the American Thoracic Society, 2008 Despite the high efficacy of continuous positive airway pressure (CPAP) to reverse upper airway obstruction in sleep apnea, treatment effectiveness is limited by variable adherence to prescribed therapy.
T. Weaver, R. Grunstein
semanticscholar +1 more source
Advanced Science, EarlyView.Plant‐derived bioactive molecules with low solubility and permeability induce hepatocyte injury, though the mechanisms driving their hepatic effects remain poorly understood. This study identifies a novel transport pathway in which poorly soluble indirubin accumulates in the liver via macrophage‐mediated uptake in Peyer's patches, exacerbating hepatic ...
Yiqi Xu +9 more
wiley +1 more source
United airway disease: current perspectives
Journal of Asthma and Allergy, 2016 Upper and lower airways are considered a unified morphological and functional unit, and the connection existing between them has been observed for many years, both in health and in disease.
P. Giavina-Bianchi +4 more
semanticscholar +1 more source
Advanced Science, EarlyView.This work unravels a novel function of CD103+ T cells in eradicating oxidative‐stressed somatic cells to prevent lung tumorigenesis and identifies specific CD103+ T cell‐decline as a key feature in the aged lung. This comprehensive study highlights the contribution of immuno‐dysregulation to the high incidence of aging‐associated lung cancers ...
Yu Xu +7 more
wiley +1 more source
The Vortex: a universal 'high-acuity implementation tool' for emergency airway management.
British Journal of Anaesthesia, 2016 Factors influencing performance during emergency airway management can be broadly divided into issues with preparation and those with implementation. Effective design of resources that provide guidance on management requires consideration of the context ...
N. Chrimes
semanticscholar +1 more source
Advanced Science, EarlyView.Pulmonary fibrosis (PF) is promoted by NETs that induce fibroblast activation. PEG‐PIm, a polymeric artificial DNase is reported that efficiently degrades NET‐DNA via phosphodiester bond hydrolysis. Inhalation of PEG‐PIm in a mouse PF model prevents fibroblast activation and fibrosis progression, offering a promising therapeutic strategy for NET ...
Yibo Du +7 more
wiley +1 more source
Transcriptomic characterization of the human segmental endotoxin challenge model
Scientific ReportsSegmental instillation of lipopolysaccharide (LPS) by bronchoscopy safely induces transient airway inflammation in human lungs. This model enables investigation of pulmonary inflammatory mechanisms as well as pharmacodynamic analysis of investigational ...
Christina Gress +7 more
doaj +1 more source
Annals of Gastroenterological Surgery, EarlyView.Abstract We reviewed the current status and perspectives on salvage esophagectomy for initially unresectable locally advanced esophageal squamous cell carcinoma (ESCC) in the era of minimally invasive surgery and immunotherapy. Although the standard treatment for these patients is definitive chemoradiotherapy (CRT), the complete response rate to CRT ...
Hiroshi Saeki +4 more
wiley +1 more source
Annals of Gastroenterological Surgery, EarlyView.Adequate contact between the intubation tube and the vocal cord muscles is crucial for effective intraoperative nerve monitoring use during esophagectomy. Additionally, intraoperative posture significantly affects diagnostic outcomes and should be carefully considered.
Masami Yuda +9 more
wiley +1 more source
High urinary desmosine is associated with long-term mortality in patients with COPD
ERJ Open Research, 2023 Changhwan Kim +11 more
doaj +1 more source