Results 11 to 20 of about 1,147,551 (385)

Human Neutrophil Elastase Degrades SPLUNC1 and Impairs Airway Epithelial Defense against Bacteria [PDF]

, 2013
Background:Acute exacerbations of chronic obstructive pulmonary disease (AECOPD) are a significant cause of mortality of COPD patients, and pose a huge burden on healthcare. One of the major causes of AECOPD is airway bacterial (e.g.
Bowler, RP, Chu, HW, Jiang, D, Schnell, C, Wenzel, SE, Wu, Q   +5 more
core   +15 more sources

SARS-CoV2 in public spaces in West London, UK during COVID-19 pandemic

BMJ Open Respiratory Research, 2023
Background Spread of SARS-CoV2 by aerosol is considered an important mode of transmission over distances >2 m, particularly indoors.Objectives We determined whether SARS-CoV2 could be detected in the air of enclosed/semi-enclosed public spaces.Methods
Prashant Kumar, Kian Fan Chung, Ian Adcock, Pankaj K Bhavsar, Hisham Abubakar-Waziri, Gopinath Kalaiarasan, Rebecca Wawman, Faye Hobbs, Claire Dilliway, Fangxin Fang, Christopher Pain, Alexandra Porter, Emma Ransome, Vincent Savolainen   +13 more
doaj   +1 more source

Chloride channels regulate differentiation and barrier functions of the mammalian airway. [PDF]

, 2020
The conducting airway forms a protective mucosal barrier and is the primary target of airway disorders. The molecular events required for the formation and function of the airway mucosal barrier, as well as the mechanisms by which barrier dysfunction ...
Caplan, Michael J, Chen, Yuzhang, Darmanis, Spyros, He, Mu, Jan, Lily Yeh, Jan, Yuh Nung, Le, Daniel D, Li, Ke-Xin, Neff, Norma, Padovano, Valeria, Sinclair, Adriane W, Sit, Rene, Tan, Michelle, Wu, Bing, Ye, Wenlei   +14 more
core   +1 more source

Cytomegalovirus serology in young to mid‐adult life and decline of lung function

The Clinical Respiratory Journal, 2023
Introduction Cytomegalovirus (CMV) seropositivity has been recently linked to severity and progression of asthma, cystic fibrosis, and chronic obstructive pulmonary disease (COPD). To date, no longitudinal study has addressed the relation of CMV serology
Raffaella Nenna, Jing Zhai, Amber Spangenberg, Duane L. Sherrill, Fernando D. Martinez, Marilyn Halonen, Stefano Guerra   +6 more
doaj   +1 more source

Evaluation of Swab-Seq as a scalable, sensitive assay for community surveillance of SARS-CoV-2 infection

Scientific Reports, 2022
The ongoing SARS-CoV-2 pandemic and subsequent demand for viral testing has led to issues in scaling diagnostic lab efforts and in securing basic supplies for collection and processing of samples. This has motivated efforts by the scientific community to
HyunJin Kang, Sheilah Allison, Amber Spangenberg, Tara Carr, Ryan Sprissler, Marilyn Halonen, Darren A. Cusanovich   +6 more
doaj   +1 more source

Ultrasound cavitation: a reliable non-enzymatic method for adipose-derived mesenchymal stem cell (ADSC) isolation

Stem Cell Research & Therapy, 2023
Background Adipose tissue is known to serve as an abundant and readily accessible source of adipose-derived stem cells (ADSCs) as an alternative to bone marrow.
Joo-Hoo Park, Yujin Choi, Jae-Min Shin, Hyun-Woo Yang, Seong-Ho Jeong, Il-Ho Park   +5 more
doaj   +1 more source

High cytomegalovirus serology and subsequent COPD-related mortality: a longitudinal study

ERJ Open Research, 2020
Background Positive serology for cytomegalovirus (CMV) has been associated with all-cause mortality risk but its role in COPD mortality is unknown. The objective of the present study was to assess the relationship between CMV serology and COPD mortality.
Raffaella Nenna, Jing Zhai, Samuel E. Packard, Amber Spangenberg, Duane L. Sherrill, Fernando D. Martinez, Marilyn Halonen, Stefano Guerra   +7 more
doaj   +1 more source

Consensus guidelines for managing the airway in patients with COVID‐19

Anaesthesia, 2020
Severe acute respiratory syndrome‐corona virus‐2, which causes coronavirus disease 2019 (COVID‐19), is highly contagious. Airway management of patients with COVID‐19 is high risk to staff and patients. We aimed to develop principles for airway management
T. Cook, K. El-Boghdadly, B. Mcguire, A. McNarry, A. Patel, A. Higgs   +5 more
semanticscholar   +1 more source

Myeloid-associated differentiation marker is a novel SP-A-associated transmembrane protein whose expression on airway epithelial cells correlates with asthma severity

Scientific Reports, 2021
Surfactant protein A (SP-A) is well-known for its protective role in pulmonary immunity. Previous studies from our group have shown that SP-A mediates eosinophil activities, including degranulation and apoptosis.
Alane Blythe C. Dy, Paul R. Langlais, Natalie K. Barker, Kenneth J. Addison, Sasipa Tanyaratsrisakul, Scott Boitano, Stephanie A. Christenson, Monica Kraft, Deborah Meyers, Eugene R. Bleecker, Xingnan Li, Julie G. Ledford   +11 more
doaj   +1 more source

Within-session variability as quality control for oscillometry in health and disease

ERJ Open Research, 2021
Oscillometry is increasingly adopted in respiratory clinics, but many recommendations regarding measurement settings and quality control remain subjective.
Louise M. Harkness, Kieran Patel, Farid Sanai, Sandra Rutting, Alice M. Cottee, Claude S. Farah, Robin E. Schoeffel, Gregory G. King, Cindy Thamrin   +8 more
doaj   +1 more source