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Detecting Alterations in Pulmonary Airway Development with Airway-by-Airway Comparison [PDF]
Neonatal and postnatal exposures to air pollutants have adverse effects on lung development resulting in airway structure changes. Usually, generation-averaged analysis of airway geometric parameters is employed to differentiate between pulmonary airway trees.
Lee, DongYoub+2 more
openaire +5 more sources
Alteration of cystic airway mesenchyme in congenital pulmonary airway malformation. [PDF]
Congenital pulmonary airway malformation (CPAM) is the most common congenital lesion detected in the neonatal lung, which may lead to respiratory distress, infection, and pneumothorax.
Jiang, Yi+9 more
core +3 more sources
Reduced Local Response to Corticosteroids in Eosinophilic Chronic Rhinosinusitis with Asthma
Eosinophilic chronic rhinosinusitis (ECRS), a subgroup of chronic rhinosinusitis with nasal polyps, is recognized as a refractory eosinophilic disorder characterized by both upper and lower airway inflammation.
Yoshiki Kobayashi+7 more
doaj +1 more source
Airway Resistance, Airway Conductance, Specific Airway Resistance, and Specific Airway Conductance in Children [PDF]
In 82 healthy children and in asthmatic children before and during positive allergen provocation test, airway resistance (Raw), airway conductance (Gaw), specific airway resistance (SRaw), and specific airway conductance (SGaw) were measured by body plethysmography during quiet breathing.
M. Leben, H von der Hardt
openaire +3 more sources
On the Role of Mechanics in Chronic Lung Disease. [PDF]
Progressive airflow obstruction is a classical hallmark of chronic lung disease, affecting more than one fourth of the adult population. As the disease progresses, the inner layer of the airway wall grows, folds inwards, and narrows the lumen.
Eskandari, Mona+2 more
core +3 more sources
Asthma is an inflammatory disease of the airways that may result from exposure to allergens or other environmental irritants, resulting in bronchoconstriction, wheezing, and shortness of breath.
Kenneth P. Hough+6 more
semanticscholar +1 more source
Lower airway dysbiosis affects lung cancer progression.
In lung cancer, enrichment of the lower airway microbiota with oral commensals commonly occurs and ex vivo models support that some of these bacteria can trigger host transcriptomic signatures associated with carcinogenesis. Here, we show that this lower
Jun-Chieh J. Tsay+41 more
semanticscholar +1 more source
TGF-β1 Activates Nasal Fibroblasts through the Induction of Endoplasmic Reticulum Stress
(1) Background: Tissue remodeling and extracellular matrix (ECM) accumulation contribute to the development of chronic inflammatory diseases of the upper airway.
Jae-Min Shin+5 more
doaj +1 more source
Airway Inflammation and Airway Hyperresponsiveness [PDF]
Airway inflammation is a complex inflammatory process of airways involving the contribution of various cells, recruited and activated in asthmatic conditions, and the mediators released by them. However, major components contributing to this inflammation are eosinophils, mast cells, and lymphocytes.
Inshah Din, Sheikh Rayees
openaire +2 more sources
Macrophage TNF-α mediates parathion-induced airway hyperreactivity in guinea pigs. [PDF]
Organophosphorus pesticides (OPs) are implicated in human asthma. We previously demonstrated that, at concentrations that do not inhibit acetylcholinesterase activity, the OP parathion causes airway hyperreactivity in guinea pigs as a result of ...
Allison D. Fryer+12 more
core +1 more source