Results 21 to 30 of about 783,276 (359)
Expression of the SARS-CoV-2 ACE2 Receptor in the Human Airway Epithelium
American Journal of Respiratory and Critical Care Medicine, 2020 Rationale: Infection with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes coronavirus disease (COVID-19), a predominantly respiratory illness.
Haijun Zhang +6 more
semanticscholar +1 more source
Airway Resistance, Airway Conductance, Specific Airway Resistance, and Specific Airway Conductance in Children [PDF]
Pediatric Research, 1983 In 82 healthy children and in asthmatic children before and during positive allergen provocation test, airway resistance (Raw), airway conductance (Gaw), specific airway resistance (SRaw), and specific airway conductance (SGaw) were measured by body plethysmography during quiet breathing.
M. Leben, H von der Hardt
openaire +3 more sources
Lower airway dysbiosis affects lung cancer progression.
Cancer Discovery, 2020 In lung cancer, enrichment of the lower airway microbiota with oral commensals commonly occurs and ex vivo models support that some of these bacteria can trigger host transcriptomic signatures associated with carcinogenesis. Here, we show that this lower
Jun-Chieh J. Tsay +41 more
semanticscholar +1 more source
TGF-β1 Activates Nasal Fibroblasts through the Induction of Endoplasmic Reticulum Stress
Biomolecules, 2020 (1) Background: Tissue remodeling and extracellular matrix (ECM) accumulation contribute to the development of chronic inflammatory diseases of the upper airway.
Jae-Min Shin +5 more
doaj +1 more source
A revised airway epithelial hierarchy includes CFTR-expressing ionocytes
Nature, 2018 The airways of the lung are the primary sites of disease in asthma and cystic fibrosis. Here we study the cellular composition and hierarchy of the mouse tracheal epithelium by single-cell RNA-sequencing (scRNA-seq) and in vivo lineage tracing.
Daniel T. Montoro +28 more
semanticscholar +1 more source
Airway Remodeling in Asthma: Tumor of the Airway? [PDF]
Respiration, 2013 properties and the therapy has been shown to have an acute and sustained beneficial effect on lung function (changes in FEV 1 ) in chronic persistent asthma [6] . Antileukotrienes do not have major side effects and appear to be well tolerated by most patients [7] , but a limitation of their widespread use may be due to the large percentage of ...
Stephan F. van Eeden, Chun Y. Seow
openaire +3 more sources
Airway Inflammation and Airway Hyperresponsiveness [PDF]
, 2021 Airway inflammation is a complex inflammatory process of airways involving the contribution of various cells, recruited and activated in asthmatic conditions, and the mediators released by them. However, major components contributing to this inflammation are eosinophils, mast cells, and lymphocytes.
Inshah Din, Sheikh Rayees
openaire +2 more sources
Long‐term expanding human airway organoids for disease modeling
EMBO Journal, 2019 Organoids are self‐organizing 3D structures grown from stem cells that recapitulate essential aspects of organ structure and function. Here, we describe a method to establish long‐term‐expanding human airway organoids from broncho‐alveolar resections or ...
Norman Sachs +47 more
semanticscholar +1 more source
Role of IL‐25, IL‐33, and TSLP in triggering united airway diseases toward type 2 inflammation
Allergy. European Journal of Allergy and Clinical Immunology, 2020 Under the concept of "united airway diseases," the airway is a single organ wherein upper and lower airway diseases are commonly comorbid. The upper and lower airways are lined with respiratory epithelium that plays a vital role in immune surveillance ...
H. Hong +4 more
semanticscholar +1 more source
British Journal of Anaesthesia, 2015 These guidelines provide a strategy to manage unanticipated difficulty with tracheal intubation. They are founded on published evidence. Where evidence is lacking, they have been directed by feedback from members of the Difficult Airway Society and based
C. Frerk +8 more
semanticscholar +1 more source