Results 31 to 40 of about 1,147,551 (385)

Expression of the SARS-CoV-2 ACE2 Receptor in the Human Airway Epithelium

American Journal of Respiratory and Critical Care Medicine, 2020
Rationale: Infection with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes coronavirus disease (COVID-19), a predominantly respiratory illness.
Haijun Zhang, M. Rostami, P. Leopold, J. Mezey, S. O'Beirne, Y. Strulovici-Barel, R. Crystal   +6 more
semanticscholar   +1 more source

Airway Remodeling in Asthma: Tumor of the Airway? [PDF]

Respiration, 2013
properties and the therapy has been shown to have an acute and sustained beneficial effect on lung function (changes in FEV 1 ) in chronic persistent asthma [6] . Antileukotrienes do not have major side effects and appear to be well tolerated by most patients [7] , but a limitation of their widespread use may be due to the large percentage of ...
Stephan F. van Eeden, Chun Y. Seow
openaire   +3 more sources

Flow-volume curve analysis for predicting recurrence after endoscopic dilation of airway stenosis [PDF]

, 2019
The flow-volume curve is a simple test for diagnosing upper airway obstruction. We evaluated its use to predict recurrence in patients undergoing endoscopic dilation for treatment of benign upper airway ...
Andreetti, Claudio, Ardò, Nicoletta, Fiorelli, Alfonso, Loizzi, Domenico, Loizzi, Michele, Messina, Gaetana, Poggi, Camilla, Rendina, Erino Angelo, Santini, Mario, Serra, Nicola, Sollitto, Francesco, Venuta, Federico   +11 more
core   +1 more source

A revised airway epithelial hierarchy includes CFTR-expressing ionocytes

Nature, 2018
The airways of the lung are the primary sites of disease in asthma and cystic fibrosis. Here we study the cellular composition and hierarchy of the mouse tracheal epithelium by single-cell RNA-sequencing (scRNA-seq) and in vivo lineage tracing.
Daniel T. Montoro, Adam L. Haber, Moshe Biton, V. Vinarský, B. Lin, S. Birket, F. Yuan, Sijia Chen, H. Leung, Jorge Villoria, Noga Rogel, Grace Burgin, Alexander M. Tsankov, Avinash Waghray, M. Slyper, Julia Waldman, Lan Nguyen, Danielle Dionne, O. Rozenblatt-Rosen, P. R. Tata, H. Mou, M. Shivaraju, H. Bihler, M. Mense, G. Tearney, S. Rowe, J. Engelhardt, A. Regev, J. Rajagopal   +28 more
semanticscholar   +1 more source

Role of IL‐25, IL‐33, and TSLP in triggering united airway diseases toward type 2 inflammation

Allergy. European Journal of Allergy and Clinical Immunology, 2020
Under the concept of "united airway diseases," the airway is a single organ wherein upper and lower airway diseases are commonly comorbid. The upper and lower airways are lined with respiratory epithelium that plays a vital role in immune surveillance ...
H. Hong, Shumin Liao, Fenghong Chen, Qintai Yang, D. Wang   +4 more
semanticscholar   +1 more source

Impending Total Airway Collapse Involving a Maxillary Removable Partial Denture: A Clinical Report [PDF]

, 2018
This article presents a rare incident of a bilateral maxillary removable partial denture as an airway foreign body. The removable partial denture and the surrounding soft tissue irritation caused partial obstruction of the airway.
Maroulakos, Georgios, Voulgarelis, Stylianos   +1 more
core   +2 more sources

Long‐term expanding human airway organoids for disease modeling

EMBO Journal, 2019
Organoids are self‐organizing 3D structures grown from stem cells that recapitulate essential aspects of organ structure and function. Here, we describe a method to establish long‐term‐expanding human airway organoids from broncho‐alveolar resections or ...
Norman Sachs, A. Papaspyropoulos, D. Z. Zomer-van Ommen, Inha Heo, L. Böttinger, Dymph Klay, F. Weeber, Guizela Huelsz-Prince, Nino Iakobachvili, G. Amatngalim, J. Ligt, A. Hoeck, N. Proost, M. Viveen, A. Lyubimova, Luc Teeven, Sepideh Derakhshan, J. Korving, H. Begthel, J. Dekkers, Kuldeep Kumawat, E. Ramos, Matthijs FM Oosterhout, G. Offerhaus, Dominique J Wiener, E. P. Olimpio, K. Dijkstra, E. Smit, Maarten Linden, S. Jaksani, M. Ven, J. Jonkers, A. Rios, E. Voest, Coline HM Moorsel, C. Ent, E. Cuppen, A. Oudenaarden, F. Coenjaerts, L. Meyaard, L. Bont, P. Peters, S. Tans, J. S. Zon, S. Boj, R. Vries, J. Beekman, H. Clevers   +47 more
semanticscholar   +1 more source

Inflammatory cytokines can be monitored in exhaled breath particles following segmental and inhalation endotoxin challenge in healthy volunteers

Scientific Reports, 2022
Particles in exhaled air (PEx) are generated when collapsed small airways reopen during breathing. PEx can be noninvasively collected by particle impaction, allowing the analysis of undiluted epithelial lining fluid (ELF).
Olaf Holz, Meike Müller, Saskia Carstensen, Anna-Carin Olin, Jens M. Hohlfeld   +4 more
doaj   +1 more source

Patterns of recruitment and injury in a heterogeneous airway network model [PDF]

, 2015
In respiratory distress, lung airways become flooded with liquid and may collapse due to surface-tension forces acting on air-liquid interfaces, inhibiting gas exchange.
Cressoni M, Murphy SL, Oliver E. Jensen, Peter S. Stewart, The Acute Respiratory Distress Syndrome Network, Weibel ER   +5 more
core   +1 more source

Difficult Airway Society 2015 guidelines for management of unanticipated difficult intubation in adults

British Journal of Anaesthesia, 2015
These guidelines provide a strategy to manage unanticipated difficulty with tracheal intubation. They are founded on published evidence. Where evidence is lacking, they have been directed by feedback from members of the Difficult Airway Society and based
C. Frerk, V. Mitchell, A. McNarry, C. Mendonca, R. Bhagrath, Anil K Patel, E. O'sullivan, N. Woodall, I. Ahmad   +8 more
semanticscholar   +1 more source