Results 51 to 60 of about 773,643 (383)
Frontiers in Immunology, 2018 Background: Eosinophilic chronic rhinosinusitis (ECRS) is a subtype of chronic rhinosinusitis with nasal polyps in Japanese. ECRS highly associated with asthma is a refractory eosinophilic airway inflammation and requires comprehensive care as part of ...
Yoshiki Kobayashi +10 more
doaj +1 more source
Journal for ImmunoTherapy of Cancer, 2021 Background The interplay of immune and cancer cells takes place in the tumor microenvironment where multiple signals are exchanged. The transforming growth factor beta (TGFB) pathway is known to be dysregulated in lung cancer and can impede an effective ...
Sebastian Marwitz +4 more
doaj +1 more source
British Journal of Anaesthesia, 2011 BACKGROUND This project was devised to estimate the incidence of major complications of airway management during anaesthesia in the UK and to study these events.
T. Cook, N. Woodall, C. Frerk
semanticscholar +1 more source
BMC Pulmonary Medicine, 2023 Background Our study aimed to investigate whether serum total IgE and blood eosinophils were associated with radiological features of bronchiectasis in a Chinese cohort.
Jiaqi Ren +6 more
doaj +1 more source
Differentiated human airway organoids to assess infectivity of emerging influenza virus
Proceedings of the National Academy of Sciences of the United States of America, 2018 Significance Influenza virus infection represents a major threat to public health worldwide. There is no biologically relevant, reproducible, and readily available in vitro model for predicting the infectivity of influenza viruses in humans. Based on the
Jie Zhou +17 more
semanticscholar +1 more source
Airway measurement by refinement of synthetic images improves mortality prediction in idiopathic pulmonary fibrosis [PDF]
arXiv, 2022 Several chronic lung diseases, like idiopathic pulmonary fibrosis (IPF) are characterised by abnormal dilatation of the airways. Quantification of airway features on computed tomography (CT) can help characterise disease progression. Physics based airway measurement algorithms have been developed, but have met with limited success in part due to the ...
arxiv
Small airway-on-a-chip enables analysis of human lung inflammation and drug responses in vitro
Nature Methods, 2015 Here we describe the development of a human lung 'small airway-on-a-chip' containing a differentiated, mucociliary bronchiolar epithelium and an underlying microvascular endothelium that experiences fluid flow, which allows for analysis of organ-level ...
K. Benam +12 more
semanticscholar +1 more source
Bicaudal D1 impairs autophagosome maturation in chronic obstructive pulmonary disease
FASEB BioAdvances, 2019 Bicaudal D1 (BICD1), an adaptor for the dynein‐dynactin motor complex, has been identified as a susceptibility gene in chronic obstructive pulmonary disease (COPD).
Nicolas Mercado +8 more
doaj +1 more source
EBioMedicine, 2017 Background: Rhinovirus infection is a major cause of asthma exacerbations. Objectives: We studied nasal and bronchial mucosal inflammatory responses during experimental rhinovirus-induced asthma exacerbations. Methods: We used nasosorption on days 0, 2–5
Trevor T. Hansel +25 more
doaj +1 more source
Comprehensive clinical evaluation of novel 4DCT‐based lung function imaging methods
Journal of Applied Clinical Medical Physics, EarlyView.Abstract Purpose Methods have been developed that apply image processing to 4DCTs to generate 4DCT‐ventilation/perfusion lung imaging. Traditional methods for 4DCT‐ventilation rely on Hounsfield‐Unit (HU) density‐change methods and suffer from poor numerical robustness while not providing 4DCT‐perfusion data.
Ehsan Golkar +6 more
wiley +1 more source