Can HRCT be used as a marker of airway remodelling in children with difficult asthma? [PDF]
, 2006 BACKGROUND: Whole airway wall thickening on high resolution computed tomography (HRCT) is reported to parallel thickening of the bronchial epithelial reticular basement membrane (RBM) in adult asthmatics. A similar relationship in children with difficult
A Barbato +23 more
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Journal of the American Medical Association (JAMA), 2018 Importance The optimal approach to airway management during out-of-hospital cardiac arrest is unknown. Objective To determine whether a supraglottic airway device (SGA) is superior to tracheal intubation (TI) as the initial advanced airway management ...
J. Benger +17 more
semanticscholar +1 more source
Effect of Air Pollutants on Allergic Inflammation in Structural Cells of the Nasal Mucosa [PDF]
Clinical and Experimental OtorhinolaryngologyObjectives. Air pollution is an increasing global concern, and its effect on allergic inflammation has attracted the attention of many researchers. Particulate matter (PM) is a major component of ambient air pollution, and heavy metals are the primary ...
Joo-Hoo Park +4 more
doaj +1 more source
Bronchoscopy, Imaging, and Concurrent Diseases in Dogs with Bronchiectasis: (2003-2014). [PDF]
, 2015 BackgroundBronchiectasis is a permanent and debilitating sequel to chronic or severe airway injury, however, diseases associated with this condition are poorly defined.ObjectiveTo evaluate results of diagnostic tests used to document bronchiectasis and ...
Byrne, BA +4 more
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Frontiers in Allergy, 2021 Background: European patients with chronic rhinosinusitis with nasal polyps (CRSwNP) have had only limited occasions to unite to have their voices heard, hence missing the opportunity to contribute to the improvement of CRSwNP care.Aims: To identify ...
N. Claeys +15 more
doaj +1 more source
Manifesto on small airway involvement and management in asthma and chronic obstructive pulmonary disease: an Interasma (Global Asthma Association - GAA) and World Allergy Organization (WAO) document endorsed by Allergic Rhinitis and its Impact on Asthma (ARIA) and Global Allergy and Asthma European Network (GA2LEN) [PDF]
, 2016 Evidence that enables us to identify, assess, and access the small airways in asthma and chronic obstructive pulmonary disease (COPD) has led INTERASMA (Global Asthma Association) and WAO to take a position on the role of the small airways in these ...
A. Cruz +51 more
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Airway Microbiota Is Associated with Upregulation of the PI3K Pathway in Lung Cancer
American Journal of Respiratory and Critical Care Medicine, 2018 Rationale: In lung cancer, upregulation of the PI3K (phosphoinositide 3‐kinase) pathway is an early event that contributes to cell proliferation, survival, and tissue invasion.
J. Tsay +21 more
semanticscholar +1 more source
Journal for ImmunoTherapy of Cancer, 2021 Background The interplay of immune and cancer cells takes place in the tumor microenvironment where multiple signals are exchanged. The transforming growth factor beta (TGFB) pathway is known to be dysregulated in lung cancer and can impede an effective ...
Sebastian Marwitz +4 more
doaj +1 more source
Optimisation of growth conditions for ovine airway epithelial cell differentiation at an air-liquid interface [PDF]
, 2018 Respiratory tract infections are of significant concern in the agriculture industry. There is a requirement for the development of well-characterised in vitro epithelial cell culture models in order to dissect the diverse molecular interactions occurring
Berry, Catherine C. +3 more
core +2 more sources
Bicaudal D1 impairs autophagosome maturation in chronic obstructive pulmonary disease
FASEB BioAdvances, 2019 Bicaudal D1 (BICD1), an adaptor for the dynein‐dynactin motor complex, has been identified as a susceptibility gene in chronic obstructive pulmonary disease (COPD).
Nicolas Mercado +8 more
doaj +1 more source