Results 41 to 50 of about 39,928 (244)

Macrophage TNF-α mediates parathion-induced airway hyperreactivity in guinea pigs. [PDF]

open access: yes, 2013
Organophosphorus pesticides (OPs) are implicated in human asthma. We previously demonstrated that, at concentrations that do not inhibit acetylcholinesterase activity, the OP parathion causes airway hyperreactivity in guinea pigs as a result of ...
Allison D. Fryer   +12 more
core   +1 more source

Endogenous Ceramide 24:1 Constrains Th17‐Driven Neutrophilic Inflammation by Antagonizing EP2 Signaling

open access: yesAdvanced Science, EarlyView.
Cer24:1 levels are reduced in neutrophilic asthma and inversely correlate with disease severity and airway neutrophilia. Restoring Cer24:1 suppresses pathogenic Th17 differentiation by engaging EP2 on CD4+ T cells, thereby dampening the JAK2–STAT3–RORγt axis and reducing IL‐17 production.
Huan Liu   +11 more
wiley   +1 more source

Vocal cord dysfunction and lyrangeal hyper-responsiveness: a function of altered autonomic balance? [PDF]

open access: yes, 2002
The interrelationships between vocal cord dysfunction and laryngeal hyperresponsiveness may have profound implications in the diagnosis and management of patients with difficult respiratory ...
Ayers, J.G., Gabbott, P.L.G.
core  

Clinical Characteristics of Geriatric Asthma in Guangxi of China: A Retrospective Comparative Descriptive Study

open access: yesAGING MEDICINE, EarlyView.
Geriatric asthmatics exhibit more comorbidities, poorer lung function, higher neutrophil ratios, and elevated CRP levels. ABSTRACT Objective The research analyzed the clinical characteristics of geriatric and nongeriatric asthma cases, aiming to provide new insights into the diagnosis and management of geriatric asthma for clinicians.
Mengxia Gu   +4 more
wiley   +1 more source

CXCR1 and CXCR2 Inhibition by Ladarixin Improves Neutrophil-Dependent Airway Inflammation in Mice

open access: yesFrontiers in Immunology, 2020
RationaleIncreased IL-8 levels and neutrophil accumulation in the airways are common features found in patients affected by pulmonary diseases such as Asthma, Idiopathic Pulmonary Fibrosis, Influenza-A infection and COPD.
Matheus Silverio Mattos   +13 more
doaj   +1 more source

高齢者気管支喘息における気道過敏性と温泉療法 [PDF]

open access: yes, 2001
Clinical effects of spa therapy were examined in 150 patients with asthma in relation tobronchial hyperresponsiveness and patient age. 1. The efficacy rate of spa therapy was larger as the patient age was higher: the rate was 73.3% in patients under age ...
Ashida, Kozo   +8 more
core   +1 more source

Resveratrol Ameliorates Allergic Rhinitis by Activating SIRT1 to Disrupt the Mitochondrial ROS‐Inflammation Vicious Cycle

open access: yesFlavour and Fragrance Journal, EarlyView.
This study demonstrates that resveratrol alleviates allergic rhinitis by activating SIRT1, thereby disrupting the mitochondrial ROS‐inflammatory cycle, improving mitochondrial function, promoting anti‐inflammatory M2 macrophage polarisation, and reducing epithelial oxidative damage.
Xinyu Zhou   +6 more
wiley   +1 more source

The impact of reflexology and homeopathy added to conventional asthma treatment on markers of airway inflammation – a randomised study

open access: yesEuropean Clinical Respiratory Journal, 2020
Background Asthma is a common chronic airway disease associated with hyperresponsiveness and airway inflammation. Anti-inflammatory medication especially inhaled corticosteroids are important for control of airway inflammation, decrease of airway ...
Ayfer Topcu   +4 more
doaj   +1 more source

Protective effect of a Protein Epitope Mimetic CCR10 antagonist, POL7085, in a model of allergic eosinophilic airway inflammation [PDF]

open access: yes, 2015
BACKGROUND: Potential involvement of the CCR10/CCL28 axis was recently reported in murine models of allergic asthma. If confirmed, blockade of the CCR10 receptor would represent an alternative to current asthma therapies.
Eric Chevalier   +4 more
core   +1 more source

Biological activities and bioactive constituents of Flammulina velutipes: An updated systematic review

open access: yesJournal of the Science of Food and Agriculture, EarlyView.
Abstract Flammulina velutipes (enokitake) is an edible mushroom recognized for both its nutritional and medicinal properties. It exhibits a broad spectrum of biological activities, including antioxidant, anti‐inflammatory, antitumor, immunomodulatory, and gut microbiota‐regulating effects.
Rıdvan Özgen   +2 more
wiley   +1 more source

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