Results 111 to 120 of about 281,398 (354)
NSAIDS AS MODULATORS OF CATION CHANNELS: FENAMATES REPURPOSING IN CHANNELOPATHIES
Cationic ion channels are transmembrane proteins that regulate the flux of cations (potassium, sodium, and calcium) across cell membrane, playing a pivotal role in many cellular functions. Disruptions of their activity can lead to the so‐called genetic or acquired channelopathies, a heterogeneous group of diseases that affect multiple human systems ...
Paola Laghetti+4 more
wiley +1 more source
Emergency ventilation is an essential component of basic life support. Respiratory emergencies occur far more frequently than cardiac arrest and, if not treated promptly and effectively, may lead to cardiac arrest. Many respiratory emergencies require assisted ventilation to prevent the occurrence of hypoxemia, hypercarbia, and cardiac decompensation ...
University of Florida College of Medicine, Department of Emergency Medicine and Department of Anesthesiology, P.O. Box 100186, Gainesville, FL 32610-0186, USA ( host institution )+2 more
openaire +4 more sources
Clinically Important Endpoints in Individuals With Leukodystrophy: A Multisite Study
ABSTRACT Importance Leukodystrophies are a diverse group of rare disorders that disrupt central myelination. These disorders present with a broad spectrum of neurological severity and are associated with a range of potential secondary complications, such as scoliosis and failure of independent feeding.
Emma R. Kotes+31 more
wiley +1 more source
Anticipated and Unanticipated Difficult Airway: A Practical and Logical Approach: A Narrative Review
Stability of the airway is a fundamental element of acute care medical practice. While airway management is conceptually straightforward, the wide variety of clinical circumstances, patients, and tools can make the task of ensuring a stable, open airway ...
Zahid Hussain Khan+2 more
doaj
New and developing non-adrenoreceptor small molecule drugs for the treatment of asthma [PDF]
Introduction: Inhaled corticosteroids (ICS) alone or in combination with an inhaled long-acting beta2-agonist (LABA) are the preferred long-term treatment for adults and adolescents with symptomatic asthma.
Thomson, Neil C.
core +1 more source
Abstract Background Chronic rhinosinusitis (CRS), characterized by persistent inflammation of the nasal and sinus mucosa, exhibits an escalating global prevalence and incidence. Interleukin‐8 (IL‐8), a key chemokine driving neutrophil recruitment, is implicated in CRS pathogenesis.
Yu Song+4 more
wiley +1 more source
Airway management is critical during near-fatal obstruction of the upper airway in epiglottitis; however, this is challenging because of the sitting posture and agitated mental status of the patient.
Masayuki Ozaki, Koji Murashima
doaj +1 more source
Evaluación Bidimensional y Tridimensional de la Vía Aérea Superior [PDF]
Indexación: Scopus; Scielo.The aim of this study was to validate and correlate the two-dimensional (2D) with the three-dimensional (3D) measures of the upper airway assessment.
Araya-Díaz, P.+2 more
core +1 more source
Biomarkers of lung congestion and injury in acute heart failure
Abstract Acute heart failure (AHF) classification and management are primarily based on lung congestion and/or hypoperfusion. The quantification of the vascular and tissue lung damage is not standard practice though biomarkers of lung injury may play a relevant role in this context.
Marco Guazzi+9 more
wiley +1 more source