Results 131 to 140 of about 15,388 (248)

Profiling of human lung and gut microbiomes in different conditions of chronic obstructive pulmonary disease using ontology-based evidence synthesis and reasoning

Frontiers in Cellular and Infection Microbiology
Chronic Obstructive Pulmonary Disease (COPD) remains one of the leading global causes of morbidity and mortality, with increasing evidence highlighting microbial dysbiosis as a key factor in disease progression and exacerbation.
Yang Wang, Yang Wang, Zeyi Huang, Jie Zheng, Ou Xu, Hong Yu, Hong Yu, Xianwei Ye, Xianwei Ye, Yongqun He, Yongqun He, Yongqun He   +11 more
doaj   +1 more source

Obesity and disease severity magnify disturbed microbiome-immune interactions in asthma patients

Nature Communications, 2019
Here, the authors characterize immunological and microbiome alterations in a cohort of obese asthmatics, finding that disease severity negatively correlates with fecal abundance of Akkermansia muciniphila, and show in a mouse model that administration of
David Michalovich, Noelia Rodriguez-Perez, Sylwia Smolinska, Michal Pirozynski, David Mayhew, Sorif Uddin, Stephanie Van Horn, Milena Sokolowska, Can Altunbulakli, Andrzej Eljaszewicz, Benoit Pugin, Weronika Barcik, Magdalena Kurnik-Lucka, Ken A. Saunders, Karen D. Simpson, Peter Schmid-Grendelmeier, Ruth Ferstl, Remo Frei, Noriane Sievi, Malcolm Kohler, Pawel Gajdanowicz, Katrine B. Graversen, Katrine Lindholm Bøgh, Marek Jutel, James R. Brown, Cezmi A. Akdis, Edith M. Hessel, Liam O’Mahony   +27 more
doaj   +1 more source

Periodontal Medicine Rewired: Mechanisms Linking Periodontitis to Systemic Diseases

Journal of Periodontal Research, EarlyView.
This review reorganizes decades of research in periodontal medicine into a multi‐dimensional framework, illustrating how periodontitis influences systemic health through at least seven interconnected mechanisms. ABSTRACT Periodontitis is now recognized not merely as a localized oral condition but as a systemic disease linked to over 70 communicable and
Mario Romandini, George Hajishengallis, Mike Curtis, Giacomo Baima   +3 more
wiley   +1 more source

Microbiome and its role in bronchiectasis

Therapeutic Advances in Respiratory Disease
Bronchiectasis (BE) is a chronic respiratory disease characterized by damage to the bronchial wall structure and permanent dilation of the bronchi. The symptoms include a persistent cough, excessive production of purulent sputum, and recurrent hemoptysis.
Yiting Pan, Jin-Fu Xu
doaj   +1 more source

Antibiotic‐mediated immune modulation in periodontitis

Periodontology 2000, EarlyView.
Abstract Periodontitis is a chronic inflammatory disease affecting the supporting structures of the teeth. Although initiated by dysbiotic microbial communities, its progression is largely driven by the host's uncontrolled inflammatory response. While antibiotics have conventionally been employed in periodontitis therapy for their antimicrobial ...
Lina J. Suárez, R. M. Arce, Camila Pinheiro Furquim, Cristiane Gonçalves, Alpdogan Kantarci, Magda Feres, Nidia C. Castro dos Santos   +6 more
wiley   +1 more source

Culture enriched molecular profiling of the cystic fibrosis airway microbiome.

, 2011
The microbiome of the respiratory tract, including the nasopharyngeal and oropharyngeal microbiota, is a dynamic community of microorganisms that is highly diverse.
Rabin Harvey R., Christopher D Sibley, Harvey R. Rabin, Dowd Scot E., Christopher D. Sibley, Eshaghurshan Christina S., Parkins Michael D., Margot E Grinwis, Faria Monica M., Sibley Christopher D., Field Tyler R., Surette Michael G., Scot E. Dowd, Michael G. Surette, Christina S Eshaghurshan, Grinwis Margot E., Margot E. Grinwis, Michael D Parkins, Michael D. Parkins, Tyler R. Field, Tyler R Field, Monica M Faria, Scot E Dowd, Harvey R Rabin, Monica M. Faria, Michael G Surette, Christina S. Eshaghurshan   +26 more
core   +1 more source

An Update on Invasive Fungal Infections in Solid Organ Transplant Recipients

Transplant Infectious Disease, EarlyView.
ABSTRACT Invasive fungal infections (IFI) remain a significant infection‐related complication in solid organ transplant recipients (SOTRs), the incidence of which has not changed overtime. With a focus on studies and data published after 2019, this narrative review provides an update on the epidemiology and prevention of IFIs in SOTRs and highlights ...
Tina Marinelli, Shahid Husain
wiley   +1 more source

Fungal Airway Microbiome at Birth [PDF]

D34. INFECTIONS AND THE IMMUNE RESPONSE, 2020
K.A. Willis, A.B. Freeman, C.T. White, G. Rezonzew, A.J. Talati, J.F. Pierre, C.V. Lal   +6 more
openaire   +1 more source

Prebiotic Bimuno® GOS reduces illness symptoms and supports gut barrier function and immunity after intermittent exercise in the heat

Experimental Physiology, EarlyView.
Abstract Exercise in hot climates increases the risk of gastrointestinal (GI) disruption and respiratory illness. We investigated the effects of a 42 day prebiotic intervention on markers of intestinal epithelial injury, GI discomfort and immunity following football specific exercise in the heat and daily upper respiratory illness.
Connor J. Parker, Samantha J. Abbott, Luke R. Butterfield, Kirsty A. Hunter, Michael A. Johnson, Graham R. Sharpe, Neil C. Williams   +6 more
wiley   +1 more source

The Role of the Microbiome in Sex and Obesity Effects on Ozone-Induced Airway Hyperresponsiveness

, 2019
Obesity is a risk factor for asthma, but standard asthma therapeutics have reduced efficacy in the obese. The obese asthmatic population is predominantly female, and often suffers from non-atopic asthma.
Cho, YoungJi
core