Results 61 to 70 of about 15,388 (248)

Environmental and structural factors associated with bacterial diversity in household dust across the Arizona-Sonora border

Scientific Reports
We previously reported that asthma prevalence was higher in the United States (US) compared to Mexico (MX) (25.8% vs. 8.4%). This investigation assessed differences in microbial dust composition in relation to demographic and housing characteristics on ...
Lauren D. Benton, Nicolas Lopez-Galvez, Chloe Herman, J. Gregory Caporaso, Emily K. Cope, Cecilia Rosales, Mercedes Gameros, Nathan Lothrop, Fernando D. Martínez, Anne L. Wright, Tara F. Carr, Paloma I. Beamer   +11 more
doaj   +1 more source

Airway Microbiome DAPC R Code

, 2019
R code written for analysis of burn patient airway microbiome data using discriminant analysis of principle components (DAPC), PICRUSt to predict microbial functions, and random forests to determine functions and patient immune responses predictive of ...
Dana Walsh (5508320)
core   +1 more source

Exacerbations, antibiotics and the airway microbiome in chronic lung disease [PDF]

, 2019
This thesis investigates the airway microbiome in chronic obstructive pulmonary disease (COPD). The relationship of the airway microbiome to clinical disease characteristics and prophylactic antibiotic therapy is unknown, as are the ideal methods of ...
Brill, Simon
core   +1 more source

Female‐Specific Risk of TAS2R Variants in Chronic Rhinosinusitis: A Hospital‐Based Cohort Study From the Taiwan Precision Medicine Initiative

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Bitter taste receptors (T2Rs) function in the innate immune defense of the sinonasal mucosa; however, the genetic association between the TAS2R gene family and chronic rhinosinusitis (CRS) remains understudied in Asian populations.
Rong‐San Jiang, Man‐Wei Hua, I‐Chieh Chen, Yi‐Ming Chen, Shun‐Hung Lin, Kuan‐Yu Lai, Yi‐Chen Chen   +6 more
wiley   +1 more source

3439 Role of the Airway Microbiome in Viral Bronchiolitis Associated Respiratory Failure

Journal of Clinical and Translational Science, 2019
OBJECTIVES/SPECIFIC AIMS: This study aims to determine if a bronchiolitis specific microbiome exists and how it evolves through disease course. Objective 1.
Emily Wasserman, Stefan Worgall, Anurag Sharma   +2 more
doaj   +1 more source

Airway Prevotella promote TLR2-dependent neutrophil activation and rapid clearance of Streptococcus pneumoniae from the lung

Nature Communications, 2022
How the airway microbiome protects against bacterial pneumonia remains unclear. Here, the authors identify airway bacterial species that activate the immune system to facilitate rapid clearance of the pathogen Streptococcus pneumoniae from the lung.
Kadi J. Horn, Melissa A. Schopper, Zoe G. Drigot, Sarah E. Clark   +3 more
doaj   +1 more source

Inflammatory Endotype-Associated Airway Resistome in Chronic Obstructive Pulmonary Disease

Microbiology Spectrum, 2022
Antimicrobial resistance is a global concern in chronic respiratory diseases, including chronic obstructive pulmonary disease (COPD). The collection of antibiotic resistance genes or resistome in human airways may underlie the resistance.
Xinzhu Yi, Yanjun Li, Haiyue Liu, Xiaomin Liu, Junhao Yang, Jingyuan Gao, Yuqiong Yang, Zhenyu Liang, Fengyan Wang, Dandan Chen, Lingwei Wang, Weijuan Shi, David C. L. Lam, Martin R. Stampfli, Paul W. Jones, Rongchang Chen, Zhang Wang   +16 more
doaj   +1 more source

Novel Organelle‐Based Intracellular Immunity With Mechanistic and Therapeutic Implications

Barrier Immunity, EarlyView.
A conceptual framework illustrating how PAMPs/DAMPs initiate barrier, innate, adaptive, and intracellular immune responses, with organelle‐based intracellular immunity serving as a central integrator linking metabolism, inflammatory signaling, and therapeutic interventions to restore immune homeostasis.
Keman Xu, Shih‐Yu Hung, Fatma Saaoud, Ying Shao, Yifan Lu, Juanjuan Liu, Bo Yuan, Haiyan Xiang, Hong Wang, Xiaofeng Yang   +9 more
wiley   +1 more source

Seasonal Dynamics of the Upper Respiratory Tract Microbiome in Chronic Obstructive Pulmonary Disease

International Journal of COPD, 2023
Shuping Cai,1,2,* Jingyuan Gao,3,* Xiaomin Liu,3,* Junhao Yang,3,* Dingyun Feng,1 Guijun Li,2 Sijia Li,1 Hailing Yang,1 Zhang Wang,3 Xinzhu Yi,3 Yuqi Zhou1 1Department of Pulmonary and Critical Care Medicine, Institute of Respiratory ...
Cai S, Gao J, Liu X, Yang J, Feng D, Li G, Li S, Yang H, Wang Z, Yi X, Zhou Y   +10 more
doaj  

Transcriptomic signatures reveal systemic adaptations and immune modulation in response to training and competitive racing in horses

Equine Veterinary Journal, EarlyView.
Abstract Background The molecular mechanisms underlying adaptation to physical exertion and racing stress in horses remain incompletely understood. Peripheral blood transcriptomics offers a minimally invasive method to monitor systemic responses to exercise and identify biomarkers of adaptation or overload. Objectives To evaluate transcriptomic changes
Izabela Dąbrowska, Jowita Grzędzicka‐Agko, Paula Kiełbik, Michał Trela, Olga Witkowska‐Piłaszewicz   +4 more
wiley   +1 more source