Results 51 to 60 of about 15,388 (248)

Upper Airways Microbiota in Antibiotic-Naive Wheezing and Healthy Infants from the Tropics of Rural Ecuador [PDF]

, 2012
Background: Observations that the airway microbiome is disturbed in asthma may be confounded by the widespread use of antibiotics and inhaled steroids.
Martha Chico, Cookson, WO, Cooper, Philip J, Cardenas, Paul Andres, Cardenas Paul Andres, Chico Martha, Cox, Michael J, Carlos Arias, Moffatt Miriam F., Michael J Cox, Arias, C, Chico, Martha, Cox Michael J., Miriam F Moffatt, William Osmond Cookson, Cookson, William Osmond, Arias Carlos, Chico, M, Paul Andres Cardenas, Arias, Carlos, Moffatt, Miriam F, Cox, MJ, Cooper Philip J., Moffatt, MF, Philip J Cooper, Cardenas, PA, Cox, Michael J; id_orcid, Cookson William Osmond, Cooper, PJ, Cooper, Philip   +29 more
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The Lung Microbiome and Airway Disease [PDF]

Annals of the American Thoracic Society, 2016
Abstract A growing body of literature has demonstrated relationships between the composition of the airway microbiota (mixed-species communities of microbes that exist in the respiratory tract) and critical features of immune response and pulmonary function.
openaire   +2 more sources

The lung microbiome of Ugandan HIV-infected pneumonia patients is compositionally and functionally distinct from that of San Franciscan patients.

PLoS ONE, 2014
Sub-Saharan Africa represents 69% of the total number of individuals living with HIV infection worldwide and 72% of AIDS deaths globally. Pulmonary infection is a common and frequently fatal complication, though little is known regarding the lower airway
Shoko Iwai, Delphine Huang, Serena Fong, Leah G Jarlsberg, William Worodria, Samuel Yoo, Adithya Cattamanchi, J Lucian Davis, Sylvia Kaswabuli, Mark Segal, Laurence Huang, Susan V Lynch   +11 more
doaj   +1 more source

Volatile Organic Compounds, Bacterial Airway Microbiome, Spirometry and Exercise Performance of Patients after Surgical Repair of Congenital Diaphragmatic Hernia

Molecules, 2021
The aim of this study was to analyze the exhaled volatile organic compounds (VOCs) profile, airway microbiome, lung function and exercise performance in congenital diaphragmatic hernia (CDH) patients compared to healthy age and sex-matched controls.
Gert Warncke, Georg Singer, Jana Windhaber, Lukas Schabl, Elena Friehs, Wolfram Miekisch, Peter Gierschner, Ingeborg Klymiuk, Ernst Eber, Katarina Zeder, Andreas Pfleger, Beate Obermüller, Holger Till, Christoph Castellani   +13 more
doaj   +1 more source

Evaluation of the airway microbiome in nontuberculous mycobacteria disease [PDF]

European Respiratory Journal, 2018
Aspiration is associated with nontuberculous mycobacterial (NTM) pulmonary disease and airway dysbiosis is associated with increased inflammation. We examined whether NTM disease was associated with a distinct airway microbiota and immune profile.297 oral wash and induced sputum samples were collected from 106 participants with respiratory symptoms and
Imran Sulaiman, Benjamin G. Wu, Yonghua Li, Adrienne S. Scott, Patrick Malecha, Benjamin Scaglione, Jing Wang, Ashwin Basavaraj, Samuel Chung, Katrina Bantis, Joseph Carpenito, Jose C. Clemente, Nan Shen, Jamie Bessich, Samaan Rafeq, Gaetene Michaud, Jessica Donington, Charissa Naidoo, Grant Theron, Gail Schattner, Suzette Garofano, Rany Condos, David Kamelhar, Doreen Addrizzo-Harris, Leopoldo N. Segal   +24 more
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Oral application of vancomycin alters murine lung microbiome and pulmonary immune responses

Immunity, Inflammation and Disease, 2022
Early life exposures to antibiotics negatively impact respiratory health and are associated with an increased risk of childhood asthma. It is explained that the lung is inclined to develop chronic inflammatory phenotypes due to early antibiotic ...
Stefan Pfeiffer, Gregor Jatzlauk, Joni V. Lund, Eistine Boateng, Draginja Kovacevic, Machteld N. Hylkema, Sabine Bartel, Michael Schloter, Susanne Krauss‐Etschmann   +8 more
doaj   +1 more source

The Role of Lower Airway Dysbiosis in Asthma: Dysbiosis and Asthma

Mediators of Inflammation, 2017
With the development of culture-independent techniques, numerous studies have demonstrated that the lower airway is not sterile in health and harbors diverse microbial communities.
Junying Lu, Lingxin Xiong, Xiaohao Zhang, Zhongmin Liu, Shiji Wang, Chao Zhang, Jingtong Zheng, Guoqiang Wang, Ruipeng Zheng, Jodie L. Simpson, Fang Wang   +10 more
doaj   +1 more source

Paediatric Asthma and the Microbiome: A Systematic Review

Microorganisms, 2023
Evidence from the literature suggests an association between the microbiome and asthma development. Here, we aimed to identify the current evidence for the association between asthma and the upper airway, lower airway and/or the gut microbiome.
Marwh G. Aldriwesh, Abrar M. Al-Mutairi, Azzah S. Alharbi, Hassan Y. Aljohani, Nabeel A. Alzahrani, Reham Ajina, Abdullah M. Alanazi   +6 more
doaj   +1 more source

The upper airway microbiome in Hispanic children with cystic fibrosis

Pediatric Pulmonology, 2023
AbstractBackgroundHispanic people with cystic fibrosis (CF) have decreased life expectancy and earlier acquisition of Pseudomonas aeruginosa compared to non‐Hispanic white individuals with CF. Racial and ethnic differences in the airway microbiome of CF may contribute to known health disparity, but have not been studied.
John Palla, Santosh Thapa, Alamelu Venkatachalam, Jessica K. Runge, Theresa A. Laguna, Ruth Ann Luna   +5 more
openaire   +2 more sources

Microbiological profiles of sputum and gastric juice aspirates in Cystic Fibrosis patients [PDF]

, 2016
Gastro-Oesophageal Reflux (GOR) is a key problem in Cystic Fibrosis (CF), but the relationship between lung and gastric microbiomes is not well understood. We hypothesised that CF gastric and lung microbiomes are related. Gastric and sputum cultures were
Bourke, Stephen, Jones, R, Al-momani, H., Stewart, Christopher, Ward, C, Robertson, A. G, Griffin, S. M., Doe, S, Bourke, Stephen J., Anderson, A, Cummings, Stephen, Krishnan, A, Pearson, J, Brodlie, Malcolm, Forrest, T., Al-Momani, H, Robertson, A. G., Brodlie, M, Perry, A, Griffin, S. M, Forrest, T, Krishnan, A., Pearson, J., Ward, C., Perry, Audrey, Doe, S., Jones, R., Anderson, Arlene   +27 more
core   +1 more source