Results 31 to 40 of about 15,388 (248)

Methodological issues in airway microbiome studies [PDF]

, 2020
Background Studies on the lung microbiome face unique methodological challenges tied to the low bacterial load of acquired samples and the increased susceptibility to bacterial DNA contamination. Contamination may be introduced from i) the upper airways during sampling and ii) reagents, kits and the general laboratory environment during laboratory ...
Drengenes, Christine
openaire   +4 more sources

The airway fungal microbiome in asthma [PDF]

Clinical & Experimental Allergy, 2020
AbstractBackgroundFungal involvement in asthma is associated with severe disease. The full spectrum of fungal species in asthma is not well described and is derived largely from insensitive culture techniques.ObjectivesTo use high‐throughput sequencing to describe the airway mycobiota in asthmatics with and without fungal sensitization and healthy ...
Eva‐Maria Rick, Kerry F. Woolnough, Paul J. Seear, Abbie Fairs, Jack Satchwell, Matthew Richardson, William R. Monteiro, Michelle Craner, Michelle Bourne, Andrew J. Wardlaw, Catherine H. Pashley   +10 more
openaire   +2 more sources

Airway microbiome dynamics and relationship to ventilator‐associated infection in intubated pediatric patients [PDF]

Pediatric Pulmonology, 2022
Keiko M Tarquinio, Todd Karsies, Steven L Shein   +2 more
exaly   +2 more sources

Microbiome and disease in the upper airway [PDF]

Current Opinion in Allergy & Clinical Immunology, 2019
Purpose of review Microbiome refers to the genetic potential of resident microorganisms that inhabit a given niche. The exact role of the microbiome and its relation to chronic disease processes remains largely unknown, although various associations have been observed. We reviewed current literature investigating the microbiome
Jivianne T, Lee, Christine M, Kim, Vijay, Ramakrishnan   +2 more
openaire   +2 more sources

Role of airway epithelial cell miRNAs in asthma

Frontiers in Allergy, 2022
The airway epithelial cells and overlying layer of mucus are the first point of contact for particles entering the lung. The severity of environmental contributions to pulmonary disease initiation, progression, and exacerbation is largely determined by ...
Eistine Boateng, Draginja Kovacevic, Vladimira Oldenburg, Madeleine Rådinger, Susanne Krauss-Etschmann, Susanne Krauss-Etschmann, Susanne Krauss-Etschmann   +6 more
doaj   +1 more source

Upper respiratory tract microbiota is associated with small airway function and asthma severity

BMC Microbiology, 2023
Background Characteristics of airway microbiota might influence asthma status or asthma phenotype. Identifying the airway microbiome can help to investigate its role in the development of asthma phenotypes or small airway function.
Yi Li, Congying Zou, Jieying Li, Wen Wang, Yue Guo, Lifang Zhao, Chunguo Jiang, Peng Zhao, Xingqin An   +8 more
doaj   +1 more source

Gut microbiota–derived short‐chain fatty acids regulate group 3 innate lymphoid cells in HCC

Hepatology, EarlyView., 2022
Abstract Background and Aims Type 3 innate lymphoid cells (ILC3s) are essential for host defense against infection and tissue homeostasis. However, their role in the development of HCC has not been adequately confirmed. In this study, we investigated the immunomodulatory role of short‐chain fatty acids (SCFAs) derived from intestinal microbiota in ILC3
Chupeng Hu, Bingqing Xu, Xiaodong Wang, Wen‐Hua Wan, Jinying Lu, Deyuan Kong, Yu Jin, Wenhua You, Hua Sun, Xiaoxin Mu, Dongju Feng, Yun Chen   +11 more
wiley   +1 more source

The role of the respiratory microbiome in asthma

Frontiers in Allergy, 2023
Asthma is a common airways disease and the human microbiome plays an increasingly recognised role in asthma pathogenesis. Furthermore, the respiratory microbiome varies with asthma phenotype, endotype and disease severity.
Christina D. Campbell, Margaret Gleeson, Imran Sulaiman, Imran Sulaiman   +3 more
doaj   +1 more source

Commensal Bacteria in the Cystic Fibrosis Airway Microbiome Reduce P. aeruginosa Induced Inflammation. [PDF]

Front Cell Infect Microbiol, 2022
Es gibt keine bekannte Lungenerkrankung, die eine so frühe, chronische und intensive Entzündungsreaktion hervorruft, wie sie in den Atemwegen von Patienten mit Mukoviszidose (CF) auftritt.
Tony-Odigie A, Wilke L, Boutin S, Dalpke AH, Yi B.   +4 more
europepmc   +2 more sources

Environmental shaping of the bacterial and fungal community in infant bed dust and correlations with the airway microbiota [PDF]

, 2020
From early life, children are exposed to a multitude of environmental exposures, which may be of crucial importance for healthy development. Here, the environmental microbiota may be of particular interest as it represents the interface between ...
Lehtimäki, Jenni, Rasmussen, Morten A., Rasmussen, Morten A.,, Russel, Jakob, Mortensen, Martin S., Stokholm, Jakob, Sørensen, Søren J., Mortensen, Martin S.,, Bisgaard, Hans, Li, Xuanji,, Gupta, Shashank, Gupta, Shashank,, Hjelmsø, Mathis H.,, Bisgaard, Hans,, Li, Xuanji, Trivedi, Urvish,, Russel, Jakob,, Trivedi, Urvish, Sørensen, Søren J.,, Stokholm, Jakob,, Hjelmsø, Mathis H., Lehtimäki, Jenni,   +21 more
core   +1 more source