Results 31 to 40 of about 163,982 (309)

Importance of slow vital capacity in the detection of airway obstruction

Jornal Brasileiro de Pneumologia, 2013
OBJECTIVE: To investigate the presence of airway obstruction by determining the FEV1/FVC and FEV1/slow vital capacity (SVC) ratios. METHODS: This was a quantitative, retrospective cross-sectional study.
Ana Raquel Goncalves de Barros, Margarida Batista Pires, Nuno Miguel Ferreira Raposo   +2 more
doaj   +1 more source

Neural crest-specific loss of Bmp7 leads to midfacial hypoplasia, nasal airway obstruction and disordered breathing, modeling obstructive sleep apnea

Disease Models & Mechanisms, 2021
Pediatric obstructive sleep apnea (OSA), a relatively common sleep-related breathing disorder affecting ∼1-5% of children, is often caused by anatomical obstruction and/or collapse of the nasal and/or pharyngeal airways.
Pranidhi Baddam, Vivian Biancardi, Daniela M. Roth, Farah Eaton, Claudine Thereza-Bussolaro, Rupasri Mandal, David S. Wishart, Amy Barr, Joanna MacLean, Carlos Flores-Mir, Silvia Pagliardini, Daniel Graf   +11 more
doaj   +1 more source

Obstructive sleep apnea syndrome in the pediatric age: the role of the dentist [PDF]

, 2019
Sleep disordered breathing in children designates a wide spectrum of respiratory disorders characterized by partial or complete obstruction of the upper airways.
Di Carlo, G, Ierardo, G, Luzzi, V, Polimeni, A, Saccucci, M   +4 more
core   +1 more source

Long-term pulmonary sequelae in children with congenital diaphragmatic hernia. [PDF]

, 1997
Neonates with congenital diaphragmatic hernia (CDH) often suffer from respiratory insufficiency due to lung hypoplasia and pulmonary hypertension.
Hop, W.C.J. (Wim), IJsselstijn, H. (Hanneke), Jongste, J.C. (Johan) de, Molenaar, J. (Jan), Tibboel, D. (Dick)   +4 more
core   +5 more sources

Smoking, longer disease duration and absence of rhinosinusitis are related to fixed airway obstruction in Koreans with severe asthma: findings from the COREA study [PDF]

, 2011
Background The clinical manifestations of severe asthma are heterogeneous. Some individuals with severe asthma develop irreversible fixed airway obstruction, which is associated with poor outcomes.
Taehoon Lee, null null, Yoon Su Lee, Yun-Jeong Bae, Tae-Bum Kim, Seon Ok Kim, Sang-Heon Cho, Hee-Bom Moon, You Sook Cho   +8 more
core   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Risk factors for obstructive sleep apnea syndrome in children: state of the art [PDF]

, 2019
The obstructive sleep apnea syndrome (OSAS) represents only part of a large group of pathologies of variable entity called respiratory sleep disorders (RSD) which include simple snoring and increased upper airway resistance syndrome (UARS).
Bellini, Chiara, Cammaroto, G., Colizza, A., de Vincentiis, M., De Vito, A., Firinu, E., Gobbi, R., Greco, A., Gulotta, G., Iannella, G., Magliulo, G., Meccariello, G., Pace, A., Pelucchi, S., Polimeni, A., Vicini, C., Visconti, I. C.   +16 more
core   +2 more sources

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Lung function in Lolland‐Falster Health Study (LOFUS)

The Clinical Respiratory Journal, 2022
Background COPD prevalence in Denmark is estimated at 18% based on data from urban populations. However, studies suggest that using the clinical cut‐off for airway obstruction in population studies may overestimate prevalence.
Katja Kemp Jacobsen, Randi Jepsen, Uffe Bodtger, Knud Rasmussen, Gry St‐Martin   +4 more
doaj   +1 more source

Obstructive Sleep Apnoea: a dental perspective [PDF]

, 2003
Obstructive sleep apnoea (OSA) is regarded as a potentially life threatening breathing disorder characterised by periodic cessation of air intake during sleep.
Mulligan, Kevin M.
core