Results 51 to 60 of about 866,956 (350)

Characteristics and outcomes of male participants in the Australian Scleroderma Cohort Study (ASCS).

Arthritis Care &Research, Accepted Article.
Objective To determine the differences in demographic, serologic and clinical characteristics between male and female patients with systemic sclerosis (SSc) in an Australian cohort. Methods Retrospective observational study using data from the Australian Scleroderma Cohort Study (ASCS). Males (M) were compared to females (F) using chi‐squared, Wilcoxon
Emily Lin, Dylan Hansen, Laura Ross, Gene‐Siew Ngian, Susanna Proudman, Gabor Major, Maryam Tabesh, Mandana Nikpour, Jennifer Walker, Lauren Host, Nava Ferdowsi, Alannah Quinlivan, Wendy Stevens, Joanne Sahhar, Diane Apostolopoulos   +14 more
wiley   +1 more source

Lipid Nanoparticles for the Delivery of CRISPR/Cas9 Machinery to Enable Site‐Specific Integration of CFTR and Mutation‐Agnostic Disease Rescue

Advanced Functional Materials, EarlyView.
Lipid nanoparticles (LNPs) are optimized to co‐deliver Cas9‐encoding messenger RNA (mRNA), a single guide RNA (sgRNA) targeting the endogenous cystic fibrosis transmembrane conductance regulator (CFTR) gene, and homologous linear double‐stranded donor DNA (ldsDNA) templates encoding CFTR.
Ruth A. Foley, Paul G. Ayoub, Vrishti Sinha, Colin Juett, Alicia Sanoyca, Emily C. Duggan, Lindsay E. Lathrop, Priyanka Bhatt, Kevin Coote, Beate Illek, Brigitte N. Gomperts, Donald B. Kohn, Steven J. Jonas   +12 more
wiley   +1 more source

Predictors of tonsillectomy after previous adenoidectomy for upper airway obstruction [abstract] [PDF]

, 2010
One of the main indications for adenotonsillectomy in children is upper airway obstruction, including obstructive sleep apnea. Previous research has suggested an increased risk for requiring subsequent tonsillectomy when adenoidectomy alone is performed ...
Basler, Keith J., Mills, Jonathan C.
core  

Obstructive Sleep Apnea: Emerging Treatments Targeting the Genioglossus Muscle [PDF]

, 2019
Obstructive sleep apnea (OSA) is characterized by repetitive episodes of upper airway obstruction caused by a loss of upper airway dilator muscle tone during sleep and an inadequate compensatory response by these muscles in the context of an anatomically
Cano-Pumarega, Irene, Castillo-García, María, García-Río, Francisco, Martínez-Sánchez, Ana Belén, Mediano, Olga, Ortigado, Ana, Resano, Pilar, Romero-Peralta, Sofia, Sánchez de la Torre, Manuel   +8 more
core   +2 more sources

Respiratory Organ‐on‐a‐Chip for Disease Modeling: From Architecture to Functional Integration

Advanced Healthcare Materials, EarlyView.
Respiratory organ‐on‐a‐chip (ROC) models capture key mechanical and cellular cues of the human respiratory system, enabling quantitative dissection of disease mechanisms. This review links ROC architectures to disease modeling, functional integration, and commercialization, and proposes a decision framework that aligns model complexity with mechanistic
Jinzhuo Hu, Yongjie Tang, Sidi Liu, Tao Xu, Qian Liu   +4 more
wiley   +1 more source

SOME IMMUNE INDICATORS IN PATIENTS WITH AIRWAY OBSTRUCTION AND CONCOMITANT INTESTINAL PARASITOSES

Фундаментальная и клиническая медицина, 2018
Aim. To study basic immune indicators in patients with respiratory diseases accompanied by airway obstruction and intestinal parasitoses. Materials and Methods.
GULZAR R. Alieva, AIGYUN V. Alkhasova
doaj  

Late airway obstruction and neutrophil infiltration in sensitized mice after antigen provocation were suppressed by selective and non-selective phosphodiesterase inhibitors

Allergology International, 1997
Suppression of antigen-induced late airway obstruction associated with neutrophilic inflammation by selective and non-selective phosphodiesterase (PDE) inhibitors was investigated in mice.
Osamu Kaminuma, Shinya Murakami, Matsunobu Suko, Hideo Kikkawa, Shigeki Matsubara, Wataru Toriumi, Katsuo Ikezawa, Hirokazu Okudaira, Koji Ito   +8 more
doaj   +1 more source

Angiofibrolipoma of the soft palate: A very rare cause of upper air way obstruction in an infant.

Bhutan Health Journal, 2021
Introduction: Infants and children are very prone to air way obstruction due to smaller and immature air ways. There are multiple causes of upper airway obstruction in infants like infections, congenital lesions and rarely tumours of the upper airway ...
Sonam Gyamtsho
doaj   +1 more source

Influence of airway‐occluding instruments on airway pressure during jet ventilation for rigid bronchoscopy [PDF]

, 2017
We measured changes in airway pressure (Paw) caused by microsurgical instruments introduced into a rigid bronchoscope during high frequency jet ventilation (HFJV).
Becker, H. D., Biro, P., Herth, F., Layer, M., Seifert, B., Spahn, D. R., Wiedemann, K.   +6 more
core  

Microengineered Gradient Hydrogels for Mechanobiology

Advanced Healthcare Materials, EarlyView.
Gradient hydrogels are used to mimic the mechanical heterogeneity in native tissues, offering powerful in vitro platforms to study cell‐material interactions in diverse pathophysiological contexts. Here, we present a comprehensive review of the design and experimental considerations for stiffness gradient hydrogels, discussing exemplary achievements ...
Shin Wei Chong, Deepu Ashok, Anna Waterhouse, Marcela M. M. Bilek, Daniele Vigolo   +4 more
wiley   +1 more source