Methods of airway resistance assessment.
Airway resistance is the ratio of driving pressure to the rate of the airflow in the airways. The most frequent methods used to measure airway resistance are whole-body plethysmography, the interrupter technique and the forced oscillation technique.
Tomasz Urbankowski, T. PrzybyĆowski
semanticscholar +1 more source
Cholesterol-sensing liver X receptors stimulate Th2-driven allergic eosinophilic asthma in mice [PDF]
Introduction: Liver X receptors (LXRs) are nuclear receptors that function as cholesterol sensors and regulate cholesterol homeostasis. High cholesterol has been recognized as a risk factor in asthma; however, the mechanism of this linkage is not known.
De Beuckelaer, Ans+10 more
core +1 more source
BackgroundImpulse oscillometry (IOS) can be used to evaluate airway impedance in patients with obstructive airway diseases. Previous studies have demonstrated that IOS parameters differ between patients with bronchiectasis and healthy controls.
Cuiyan Tan+13 more
doaj +1 more source
Fructose transport-deficient Staphylococcus aureus reveals important role of epithelial glucose transporters in limiting sugar-driven bacterial growth in airway surface liquid. [PDF]
Hyperglycaemia as a result of diabetes mellitus or acute illness is associated with increased susceptibility to respiratory infection with Staphylococcus aureus.
A Brennan+50 more
core +1 more source
Exercise-Induced Bronchoconstriction Identified Using the Forced Oscillation Technique
Objective: Lung mechanics using the forced oscillation technique (FOT) is suggested to be equivalent and more sensitive in determining exercise-induced bronchoconstriction (EIB) than spirometry.
Leigh M. Seccombe+7 more
doaj +1 more source
Spirometry-based airways disease simulation and recognition using Machine Learning approaches [PDF]
The purpose of this study is to provide means to physicians for automated and fast recognition of airways diseases. In this work, we mainly focus on measures that can be easily recorded using a spirometer. The signals used in this framework are simulated using the linear bi-compartment model of the lungs.
arxiv
Estimating Airway Resistance from Forced Expiration in Spirometry
Spirometry is the gold standard to detect airflow limitation, but it does not measure airway resistance, which is one of the physiological factors behind airflow limitation. In this study, we describe the dynamics of forced expiration in spirometry using
Nilakash Das+4 more
doaj +1 more source
Impact of Airways Geometry on Transport of Gases to Blood [PDF]
Topological structure of bronchial trees affects transport of gases and aerosols in the respiratory system. We start by providing a quantitative assessment of the ability of the alternative tree representations to predict observable geometric and mechanistic characteristics, such as network resistance, dead space volume, and path length.
arxiv
Physiopathological rationale of using high-flow nasal therapy in the acute and chronic setting: A narrative review [PDF]
Chronic lung disease and admissions due to acute respiratory failure (ARF) are becoming increasingly common. Consequently, there is a growing focus on optimizing respiratory support, particularly non-invasive respiratory support, to manage these ...
Cortegiani A.+2 more
core +1 more source
A Systems Engineering Approach to Modeling and Analysis of Chronic Obstructive Pulmonary Disease (COPD) [PDF]
Chronic Obstructive Pulmonary Disease (COPD) is a progressive lung disease characterized by airflow limitation. This study develops a systems engineering framework for representing important mechanistic details of COPD in a model of the cardio-respiratory system.
arxiv