Results 31 to 40 of about 3,400,486 (392)

Characterization of orally efficacious influenza drug with high resistance barrier in ferrets and human airway epithelia

open access: yesScience Translational Medicine, 2019
A next-generation, broad-spectrum, orally efficacious influenza A and B virus inhibitor is associated with a high genetic resistance barrier. Treating flu, escaping resistance Influenza viruses can cause severe illness and death.
M. Toots   +16 more
semanticscholar   +1 more source

Plethysmographic Loops: A Window on the Lung Pathophysiology of COPD Patients

open access: yesFrontiers in Physiology, 2018
Plethysmographic alveolar pressure-flow (Palv–F) loops contain potentially relevant information about the pathophysiology of chronic obstructive pulmonary disease (COPD), but no quantitative analysis of these loops during spontaneous breathing has ever ...
Dejan Radovanovic   +5 more
doaj   +1 more source

Physical Properties of Helium and Application in Respiratory Care

open access: yesEncyclopedia, 2023
Helium is a low-density, inert, monoatomic gas that is widely used in medical applications. In respiratory care, Helium is mainly used as an adjunct therapy for patients with severe upper airway obstruction and asthma.
Eric Chappel
doaj   +1 more source

Dynamics of airflow in a short inhalation [PDF]

open access: yes, 2015
During a rapid inhalation, such as a sniff, the flow in the airways accelerates and decays quickly. The consequences for flow development and convective trans- port of an inhaled gas were investigated in a subject geometry extending from the nose to the ...
Bates, Alister   +7 more
core   +4 more sources

Cholesterol-sensing liver X receptors stimulate Th2-driven allergic eosinophilic asthma in mice [PDF]

open access: yes, 2016
Introduction: Liver X receptors (LXRs) are nuclear receptors that function as cholesterol sensors and regulate cholesterol homeostasis. High cholesterol has been recognized as a risk factor in asthma; however, the mechanism of this linkage is not known.
De Beuckelaer, Ans   +10 more
core   +1 more source

The Role of Impulse Oscillometry in Evaluating Disease Severity and Predicting the Airway Reversibility in Patients With Bronchiectasis

open access: yesFrontiers in Medicine, 2022
BackgroundImpulse oscillometry (IOS) can be used to evaluate airway impedance in patients with obstructive airway diseases. Previous studies have demonstrated that IOS parameters differ between patients with bronchiectasis and healthy controls.
Cuiyan Tan   +13 more
doaj   +1 more source

Exercise-Induced Bronchoconstriction Identified Using the Forced Oscillation Technique

open access: yesFrontiers in Physiology, 2019
Objective: Lung mechanics using the forced oscillation technique (FOT) is suggested to be equivalent and more sensitive in determining exercise-induced bronchoconstriction (EIB) than spirometry.
Leigh M. Seccombe   +7 more
doaj   +1 more source

On the Advantages of Specific Airway Resistance [PDF]

open access: yesPediatric Research, 1978
The specific airway resistance (SRaw) is a relatively precise parameter of bronchial quality and in normal children its relation with body length, although very significant (P less than 0.001), is so poor that it can safely be disregarded (Fig. 4). Also the dispersion around the mean value remains stable at any body size (Fig. 4).
I Dab, F Alexander
openaire   +3 more sources

Estimating Airway Resistance from Forced Expiration in Spirometry

open access: yesApplied Sciences, 2019
Spirometry is the gold standard to detect airflow limitation, but it does not measure airway resistance, which is one of the physiological factors behind airflow limitation. In this study, we describe the dynamics of forced expiration in spirometry using
Nilakash Das   +4 more
doaj   +1 more source

Fructose transport-deficient Staphylococcus aureus reveals important role of epithelial glucose transporters in limiting sugar-driven bacterial growth in airway surface liquid. [PDF]

open access: yes, 2014
Hyperglycaemia as a result of diabetes mellitus or acute illness is associated with increased susceptibility to respiratory infection with Staphylococcus aureus.
A Brennan   +50 more
core   +1 more source

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