Results 31 to 40 of about 3,555,053 (290)

Bronchial Asthma, Airway Remodeling and Lung Fibrosis as Successive Steps of One Process

International Journal of Molecular Sciences, 2023
Bronchial asthma is a heterogeneous disease characterized by persistent respiratory system inflammation, airway hyperreactivity, and airflow obstruction.
I. Savin, M. Zenkova, A. Sen’kova
semanticscholar   +1 more source

Evaluating the effects of vitamin D Level on airway obstruction in two asthma endotypes in humans and in two mouse models with different intake of vitamin D during early-life

Frontiers in Immunology, 2023
IntroductionAsthma is primarily divided into two categories: type 2 (T2-high) and non-type 2 (T2-low). A relationship between asthma severity and vitamin D deficiency has been identified, but its impact on each asthma endotype remains unknown.MethodsWe ...
Yan Zhou, Yali Qiu, Wuping Bao, Lei Han, Yishu Xue, Yingying Zhang, Xue Tian, Qiang Fu, Chengjian Lv, Dongning Yin, Min Zhang   +10 more
doaj   +1 more source

Cholesterol-sensing liver X receptors stimulate Th2-driven allergic eosinophilic asthma in mice [PDF]

, 2016
Introduction: Liver X receptors (LXRs) are nuclear receptors that function as cholesterol sensors and regulate cholesterol homeostasis. High cholesterol has been recognized as a risk factor in asthma; however, the mechanism of this linkage is not known.
De Beuckelaer, Ans, Grooten, Johan, Gustafsson, Jan-Ake, Lambrecht, Bart, Naessens, Thomas, Smet, Muriel, Steffensen, Knut R, Van Hoecke, Lien, Vander Beken, Seppe, Vergote, Karl, Willart, Monique   +10 more
core   +1 more source

Impulse oscillometry may be of value in detecting early effects of obesity on airway resistance

Egyptian Journal of Chest Disease and Tuberculosis, 2019
Background and objective Obesity as a major nutritional problem is badly associated with respiratory compliance. The effortless technique such as impulse oscillometry system (IOS) could have a supremacy value over the commonly used pulmonary function ...
Hossam E.M Abdel-Hamid
doaj   +1 more source

Guanylyl cyclase activation reverses resistive breathing–induced lung injury and inflammation [PDF]

, 2015
Inspiratory resistive breathing (RB), encountered in obstructive lung diseases, induces lung injury. The soluble guanylyl cyclase (sGC)/cyclic guanosine monophosphate (cGMP) pathway is down-regulated in chronic and acute animal models of RB, such as ...
Brouckaert, Peter, Dettoraki, Maria, Giannis, Athanassios, Glynos, Constantinos, Karavana, Vassiliki, Kotsikoris, Vasilis, Loverdos, Konstantinos, Magkou, Christina, Papapetropoulos, Andreas, Pavlidou, Athanasia, Perlikos, Fotis, Theocharis, Stamatios E, Topouzis, Stavros, Toumpanakis, Dimitris, Vassilakopoulos, Theodoros, Zhou, Zongmin   +15 more
core   +2 more sources

A novel approach in understanding the basic modes of ventilation in a recent generation mechanical ventilator– A review of the underlying principles

Indian Journal of Anaesthesia, 2023
Understanding the basic concepts and the dynamics of the equation of motion will help the anaesthesiologist and the intensive care physician in gaining an insight into the basics of modern mechanical ventilation. An equation of the type Vt = V0 × (1-e-kt)
Vithal Krishna Dhulkhed, Pavan Vithal Dhulkhed, Anusha Ramachandra Katti, Madhuri Kurdi, Sukhminder Jit Singh Bajwa   +4 more
doaj   +1 more source

The Relationship Between Airway Resistance, Airway Conductance and Lung Volume in Subjects of Different Age and Body Size12 [PDF]

Journal of Clinical Investigation, 1958
W. A. Briscoe, Arthur B. DuBois
openalex   +2 more sources

Exercise-Induced Bronchoconstriction Identified Using the Forced Oscillation Technique

Frontiers in Physiology, 2019
Objective: Lung mechanics using the forced oscillation technique (FOT) is suggested to be equivalent and more sensitive in determining exercise-induced bronchoconstriction (EIB) than spirometry.
Leigh M. Seccombe, Leigh M. Seccombe, Matthew J. Peters, Matthew J. Peters, Lachlan Buddle, Claude S. Farah, Claude S. Farah, Claude S. Farah   +7 more
doaj   +1 more source

Assessment of functional tests on determining resistance of respiratory tract in patients with bronchial asthma, COPD and their combination.

Medičnì Perspektivi, 2017
The mechanical properties of the respiratory tract (including airway resistance) is an important indicator of pulmonary function, and definition of resistance is used to diagnose and monitor obstructive lung diseases. This study was performed in order to
K. V. Nazarenko, S. G. Opimakh, M. O. Polianskaja   +2 more
doaj   +1 more source

Estimating Airway Resistance from Forced Expiration in Spirometry

Applied Sciences, 2019
Spirometry is the gold standard to detect airflow limitation, but it does not measure airway resistance, which is one of the physiological factors behind airflow limitation. In this study, we describe the dynamics of forced expiration in spirometry using
Nilakash Das, Kenneth Verstraete, Marko Topalovic, Jean-Marie Aerts, Wim Janssens   +4 more
doaj   +1 more source