Results 41 to 50 of about 187,291 (347)

Estimating Airway Resistance from Forced Expiration in Spirometry

Applied Sciences, 2019
Spirometry is the gold standard to detect airflow limitation, but it does not measure airway resistance, which is one of the physiological factors behind airflow limitation. In this study, we describe the dynamics of forced expiration in spirometry using
Nilakash Das, Kenneth Verstraete, Marko Topalovic, Jean-Marie Aerts, Wim Janssens   +4 more
doaj   +1 more source

The effect of lipoprotein-associated phospholipase A2 deficiency on pulmonary allergic responses in Aspergillus fumigatus sensitized mice. [PDF]

, 2012
BackgroundLipoprotein-associated phospholipase A2 (Lp-PLA2)/platelet-activating factor acetylhydrolase (PAF-AH) has been implicated in the pathogenesis of cardiovascular disease.
Fehrenbach, Melane L, Haczku, Angela, Jiang, Zhilong, Kokalari, Blerina, Macphee, Colin, Ravaioli, Giulia, Redai, Imre G, Sheardown, Steven A, Wilson, Stephen   +8 more
core   +2 more sources

Cholesterol-sensing liver X receptors stimulate Th2-driven allergic eosinophilic asthma in mice [PDF]

, 2016
Introduction: Liver X receptors (LXRs) are nuclear receptors that function as cholesterol sensors and regulate cholesterol homeostasis. High cholesterol has been recognized as a risk factor in asthma; however, the mechanism of this linkage is not known.
De Beuckelaer, Ans, Grooten, Johan, Gustafsson, Jan-Ake, Lambrecht, Bart, Naessens, Thomas, Smet, Muriel, Steffensen, Knut R, Van Hoecke, Lien, Vander Beken, Seppe, Vergote, Karl, Willart, Monique   +10 more
core   +1 more source

D-4F, an apoA-1 mimetic, decreases airway hyperresponsiveness, inflammation, and oxidative stress in a murine model of asthma[S]

Journal of Lipid Research, 2011
Asthma is characterized by oxidative stress and inflammation of the airways. Although proinflammatory lipids are involved in asthma, therapies targeting them remain lacking. Ac-DW F KA F YDKVAEK F KEA F NH2 (4F) is an apolipoprotein (apo)A-I mimetic that
S.D. Nandedkar, D. Weihrauch, H. Xu, Y. Shi, T. Feroah, W. Hutchins, D.A. Rickaby, N. Duzgunes, C.A. Hillery, K.S. Konduri, Jr.K.A. Pritchard   +10 more
doaj   +1 more source

Therapeutic alternatives with CPAP in obstructive sleep apnea [PDF]

, 2019
Obstructive Sleep Apnea (OSA), characterized by airflow cessation (apnea) or reduction (hypopnea) due to repeated pharyngeal obstructions during sleep, causes frequent disruption of sleep and hypoxic events. The condition is linked to many adverse health
Aluas, Maria, Bordea, Roxana I, Budin, Corina E, Ciumarnean, Lorena, Cozma, Angela, Gergely, Bianca D, Maierean, Anca, Man, Milena, Rajnovean, Ruxandra   +8 more
core   +3 more sources

The Role of Impulse Oscillometry in Evaluating Disease Severity and Predicting the Airway Reversibility in Patients With Bronchiectasis

Frontiers in Medicine, 2022
BackgroundImpulse oscillometry (IOS) can be used to evaluate airway impedance in patients with obstructive airway diseases. Previous studies have demonstrated that IOS parameters differ between patients with bronchiectasis and healthy controls.
Cuiyan Tan, Donghai Ma, Donghai Ma, Kongqiu Wang, Changli Tu, Meizhu Chen, Xiaobin Zheng, Yingjian Liang, Yiying Huang, Zhenguo Wang, Jian Wu, Jin Huang, Jing Liu, Jing Liu   +13 more
doaj   +1 more source

Theoretical open-loop model of respiratory mechanics in the extremely preterm infant [PDF]

, 2018
Non-invasive ventilation is increasingly used for respiratory support in preterm infants, and is associated with a lower risk of chronic lung disease.
Brandes, Matthew, Fix, Laura Ellwein, Khoury, Joseph, Linkous, Lauren, Moores, Russell, Rozycki, Henry J.   +5 more
core   +4 more sources

α-Bisabolol alleviates diesel exhaust particle-induced lung injury and mitochondrial dysfunction by regulating inflammatory, oxidative stress, and apoptotic biomarkers through the c-Jun N-terminal kinase signaling pathway

Frontiers in Pharmacology
IntroductionExposure to particulate matter ≤2.5 μm in diameter (PM2.5) is associated with adverse respiratory outcomes, including alterations to lung morphology and function.
Sumaya Beegam, Nur Elena Zaaba, Ozaz Elzaki, Abderrahim Nemmar   +3 more
doaj   +1 more source

Impulse oscillometry identifies peripheral airway dysfunction in children with adenosine deaminase deficiency. [PDF]

, 2015
Adenosine deaminase-deficient severe combined immunodeficiency (ADA-SCID) is characterized by impaired T-, B- and NK-cell function. Affected children, in addition to early onset of infections, manifest non-immunologic symptoms including pulmonary ...
Candotti, Fabio, Hershfield, Michael S, Kohn, Donald B, Komarow, Hirsh D, Metcalfe, Dean D, Sokolic, Robert, Young, Michael   +6 more
core   +2 more sources

Mechanisms and Management of Obstructive Sleep Apnea: A Translational Overview [PDF]

Clinical and Experimental Otorhinolaryngology
Obstructive sleep apnea (OSA) is a common disorder characterized by recurrent episodes of upper airway obstruction during sleep, resulting in apnea and hypopnea.
Yun Jin Kang, Chan-Soon Park
doaj   +1 more source