Results 41 to 50 of about 2,432,490 (285)

On the Advantages of Specific Airway Resistance [PDF]

Pediatric Research, 1978
The specific airway resistance (SRaw) is a relatively precise parameter of bronchial quality and in normal children its relation with body length, although very significant (P less than 0.001), is so poor that it can safely be disregarded (Fig. 4). Also the dispersion around the mean value remains stable at any body size (Fig. 4).
I, Dab, F, Alexander
openaire   +2 more sources

Measurement of airway function using invasive and non-invasive methodsin mild and severe models for allergic airway inflammation in mice [PDF]

, 2014
In this study a direct comparison was made between non-invasive and non-ventilated unrestrained whole body plethysmography (Penh) (conscious animals) and the invasive ventilated lung resistance (RL) method (anaesthetized animals) in both mild and severe ...
Johan eGarssen, Kim eVerheijden, Frank A Redegeld, Verheijden, Kim A T, Paul A. J. Henricks, Garssen, Johan, Pharmacology, Gert Folkerts, Sub Immunopharmacology, Sub Airway in vivo Pharmacology, Kim A. T. Verheijden, Redegeld, Frank A., Henricks, Paul A J, Frank A. Redegeld, Paul eHenricks, Folkerts, Gert, Gert eFolkerts, UIPS - Utrecht Institute for Pharmaceutical Sciences, Johan Garssen   +18 more
core   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Acute Effect of Submaximal Exercise on Respiratory System Impedance in Healthy Adults

Journal of Functional Morphology and Kinesiology
Background: Previous studies have experimentally investigated and simulated the effects of dynamic hyperinflation on respiratory system resistance variables in populations with different respiratory diseases.
Thales Henrique do Carmo Furquim, Daniele Oliveira dos Santos, Jéssica Perossi, Fernanda Cristina Lima, Janne Marques Silveira, Ada Clarice Gastaldi   +5 more
doaj   +1 more source

Elevated Paracellular Glucose Flux across Cystic Fibrosis Airway Epithelial Monolayers Is an Important Factor for Pseudomonas aeruginosa Growth. [PDF]

, 2013
People with cystic fibrosis (CF) who develop related diabetes (CFRD) have accelerated pulmonary decline, increased infection with antibiotic-resistant Pseudomonas aeruginosa and increased pulmonary exacerbations.
James P Garnett, Tarran Robert, Ward, Christopher, Ward Christopher, Michael A Gray, Baines, DL, Garnett, James P., Robert Tarran, Christopher Ward, Ward, C, Garnett, JP, Baker, EH, Brodlie Malcolm, Baker, Emma H., Tarran, Robert, Gray Michael A., Brodlie, Malcolm, Baker Emma H., Garnett James P., Brodlie, M, Deborah L Baines, Baines Deborah L., Gray, Michael A., Baines, Deborah L., Gray, MA, Malcolm Brodlie, Tarran, R, Emma H Baker   +27 more
core   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Risk of Narrow Upper Airway in Class II Children with Large Horizontal Maxillary Overjet Assessed By Acoustic Reflection: a Case-Control Study

eJournal of Oral Maxillofacial Research
Objectives: The aim of this case-control study was to examine upper airway by acoustic reflection in class II children with large horizontal maxillary overjet compared to children with neutral occlusion.
Camilla Hansen, Merete Bakke, Liselotte Sonnesen   +2 more
doaj   +1 more source

Gas exchange during exercise in habitually active asthmatic subjects [PDF]

, 2005
We determined the relations among gas exchange, breathing mechanics, and airway inflammation during moderate- to maximum-intensity exercise in asthmatic subjects.
Haverkamp, HC, Eldridge, MW, Rodman, JR, Pegelow, DF, Miller, JD, Romer, LM, Dempsey, JA   +6 more
core   +1 more source

Characteristics and Outcomes of Male Participants in a Multicenter Longitudinal Australian Study Cohort

Arthritis Care &Research, EarlyView.
Objective The aim of this study was to determine the differences in demographic, serologic, and clinical characteristics between male and female patients with systemic sclerosis (SSc) in an Australian cohort. Methods This was a retrospective observational study using data from the Australian Scleroderma Cohort Study.
Emily Lin, Dylan Hansen, Laura Ross, Gene‐Siew Ngian, Susanna Proudman, Gabor Major, Maryam Tabesh, Mandana Nikpour, Jennifer Walker, Lauren Host, Nava Ferdowsi, Alannah Quinlivan, Wendy Stevens, Joanne Sahhar, Diane Apostolopoulos   +14 more
wiley   +1 more source