Results 31 to 40 of about 7,085 (189)

Crisis epilépticas en niños con síndrome de Dravet en condiciones de calor extremo: estudio cualitativo de la perspectiva de los progenitores

open access: yesDevelopmental Medicine &Child Neurology, Volume 68, Issue 10, Page e168-e178, October 2026.
Resumen Objetivo Describir la experiencia de progenitores de niños y adolescentes con síndrome de Dravet en relación con el impacto de las olas de calor o las altas temperaturas ambientales en las crisis epilépticas de sus hijos, así como las estrategias de afrontamiento empleadas.
Angel Aledo‐Serrano   +8 more
wiley   +1 more source

Ecology of declining populations of gray foxes (Urocyon cinereoargenteus) in Indiana, USA Ecología de las poblaciones en declive de zorros grises (Urocyon cinereoargenteus) en Indiana, EE.UU.

open access: yesWildlife Monographs, Volume 226, Issue 1, September 2026.
We estimated seasonal space use, cover selection, and resource selection; evaluated gene flow and potential genetic barriers; and assessed cause‐specific survival rates and reproduction of radiomarked gray foxes in Indiana, USA. Our results provide evidence that gray foxes in Indiana are an edge species with relatively large home ranges, relatively low
Tim L. Hiller   +5 more
wiley   +1 more source

Kinetic Compatibility as a Predictor of PTP1B Inhibitor Combination Outcomes: An Integrated Experimental and Computational Study

open access: yesChemMedChem, Volume 21, Issue 16, 27 August 2026.
Combining PTP1B inhibitors of distinct kinetic mechanisms determines their pharmacological outcome. Integrating enzyme kinetics, docking, molecular dynamics, and membrane‐permeability simulations, we show that mechanistically compatible pairs (competitive + competitive; uncompetitive + mixed) yield additivity, whereas competitive + uncompetitive ...
Jonathan Trapala   +7 more
wiley   +1 more source

Review / Reseña: VV.AA, La despoblación del mundo rural. Algunas propuestas (prácticas y realistas) desde los ámbitos jurídico, económico y social para tratar de paliar o revertir tan denostado fenómeno. Thomson Reuters Aranzadi. Navarra. 2020 pp. 571

open access: yesBarataria, 2022
Este libro es un recopilatorio de cuatro ponencias dictadas por Umberto Eco, abordando los fenómenos migratorios y la intolerancia en la Europa de los siglos XX y XXI, como temas centrales y transversales a los principales debates políticos ...
Esteban Andrés Ramos Muslera
doaj   +1 more source

Patterns of Interploidy Admixture in Polyploid Complexes: Insights From Thymus Sect. Mastichina (Lamiaceae)

open access: yesMolecular Ecology, Volume 35, Issue 3, February 2026.
ABSTRACT Understanding gene flow between ploidy levels in polyploid complexes is essential for species delimitation and conservation. This study explores evolutionary dynamics in the polyploid complex Thymus sect. Mastichina (Lamiaceae), comprising three taxa: T. mastichina subsp. mastichina, T. mastichina subsp.
Francisco José García‐Cárdenas   +7 more
wiley   +1 more source

Development and Validation of Multivariable Machine‐Learning Models for the Prediction of Multisystemic Inflammatory Syndrome Outcomes in Latin American Children

open access: yesActa Paediatrica, Volume 115, Issue 1, Page 133-145, January 2026.
ABSTRACT Aim We aimed to develop and test machine learning algorithms for the prediction of severe outcomes associated with MIS‐C. Method An observational ambispective cohort study was conducted including children aged from 1 month to 18 years old in 84 hospitals from the REKAMLATINA (Red de la Enfermedad de Kawasaki en America Latina) network ...
Danilo Buonsenso   +86 more
wiley   +1 more source

Identifying priority areas for conservation to promote connectivity and mitigate the impacts of anthropogenic disturbance

open access: yesConservation Biology, Volume 39, Issue 6, December 2025.
Abstract As nations seek to expand protected area (PA) networks to cover 30% of land and seas by 2030 (30×30), there is an urgent need for systematic conservation planning and spatial prioritization that considers the broad range of ecological and socioeconomic factors influencing the persistence of biodiversity.
Edmond Sacre   +2 more
wiley   +1 more source

Aislamiento y circum:

open access: yesRevista Uruguaya de Psicoanálisis, 2020
Afectados, como todos, por los impactos subjetivos precipitados por el aislamiento, los psicoanalistas hemos apelado a nuestro arsenal conceptual para intentar hacerlos más comprensibles. Se ha hablado, en ese sentido, de «situación traumática compartida», se ha intentado trazar sus semejanzas y sus diferencias con las neurosis traumáticas y las ...
openaire   +1 more source

Impact of C18 Epimerization of Indole‐ and Pyrazole‐Fused 18β‐Glycyrrhetinic Acid Derivatives on PTP1B and TCPTP Inhibitory Activity: Synthesis, In Vitro, and In Silico Studies

open access: yesChemMedChem, Volume 20, Issue 22, November 18, 2025.
The indole derivative (FC‐114) and the N‐phenylpyrazole (FC‐122) of glycyrrhetinic acid are both potent inhibitors of the Protein Tyrosine Phosphatase 1B, with IC50 values of 0.48 μM and 1.15 μM, respectively. However, their activity decreases by up to four times when the 18β‐H position is epimerized to 18α‐H or when the carbonyl group at the C11 ...
Ledy De‐la‐Cruz‐Martínez   +10 more
wiley   +1 more source

Foliar spectral signatures reveal adaptive divergence in live oaks (Quercus section Virentes) across species and environmental niches

open access: yesNew Phytologist, Volume 248, Issue 1, Page 370-388, October 2025.
Summary Genomic tools have advanced our understanding of species and population structure, but distinguishing neutral from adaptive evolution remains challenging due to limited methods for measuring a broad spectrum of phenotypic traits. We used spectroscopic data from preserved leaves to test for adaptive divergence among populations of live oaks ...
Mariana S. Hernández‐Leal   +3 more
wiley   +1 more source

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