Results 21 to 30 of about 14,328 (189)

Organelle‐Resolved Tetrazine‐trans‐Cyclooctene Click Chemistry for Cargo Delivery and Release

open access: yesChemistry – A European Journal, EarlyView.
Bioorthogonal click chemistry tools provide a means for specific intracellular conjugation of molecules. In this study, we used reactive tetrazine (Tz) and TCO moieties for labeling of organelles and organelle‐specific delivery and activation of doxorubicin prodrugs.
Oleh Durydivka   +6 more
wiley   +1 more source

Kétszáz év a szavak mögött

open access: yesActa Academiae Beregsasiensis, Philologica
Tolcsvai Nagy Gábor (szerk.): Az élő Akadémia kétszáz éve. A nyelvtudomány és az MTA Budapest: Magyar Tudományos Akadémia – ELTE Humán Tudományok Központja, 2025, 1000 o.
Réka Varga
doaj   +1 more source

Akademisk karriere som «risikosport». Midlertidighet i et kjønnsperspektiv

open access: yesSøkelys på Arbeidslivet, 2019
Denne artikkelen undersøker hvorvidt midlertidige kontrakter i akademia har kjønnede konsekvenser som skaper ulikhet. En akademisk karriere anses som en individuell «risikosport», og midlertidige stillinger er knyttet til stor usikkerhet og ...
Cecilie Thun
doaj   +1 more source

Kjønn og akademia

open access: yes, 2022
Flertallet av studentene ved landets høyere utdanningsinstitusjoner er kvinner, og det er like mange kvinner som menn som tar doktorgrad. Likevel er over to tredeler av professorene ved landets universiteter og høyskoler menn. Hvordan kan vi forstå denne vedvarende kjønnsubalansen? Hva er det med akademia som gjør at kvinner faller fra på veien opp mot
Mangset, Marte   +25 more
openaire   +2 more sources

Mild C─F Activation of Azido(per)Fluoroalkanes

open access: yesChemistry – A European Journal, EarlyView.
Mild and selective activation of C(sp3)–F bonds in azido(per)fluoroalkanes using thiolates was developed, leading to novel functionalized azides. The reaction is initiated by nucleophilic attack of the sulfur atom to the terminal nitrogen of the azido group, followed by fluoride ion elimination.
Olena Shaitanova   +7 more
wiley   +1 more source

Effects of catechins, resveratrol, silymarin components and some of their conjugates on xanthine oxidase‐catalyzed xanthine and 6‐mercaptopurine oxidation

open access: yesJournal of the Science of Food and Agriculture, Volume 105, Issue 5, Page 2765-2776, 30 March 2025.
Abstract BACKGROUND Over the past two decades, the global incidence of gout has markedly increased, affecting people worldwide. Considering the side effects of xanthine oxidase (XO) inhibitor drugs (e.g. allopurinol and febuxostat) used in the treatment of hyperuricemia and gout, the potential application of phytochemicals has been widely studied.
Tímea Bencsik   +6 more
wiley   +1 more source

Identification of initial vegetation and habitat changes in small temperate fens using remote sensing

open access: yesRemote Sensing in Ecology and Conservation, EarlyView.
Temperate fens with only incipient, subtle signs of deterioration can be reliably identified using Sentinel‐2 and aerial imagery, which sensitively detect early productivity‐related structural changes. Abstract Small temperate fens rank among the most endangered habitats in temperate Europe.
Lubomír Tichý   +9 more
wiley   +1 more source

Treatment Dose Increase Versus Co‐Medication in Allergic Rhinitis: Systematic Review With Dose–Response Network Meta‐Analysis

open access: yesAllergy, EarlyView.
ABSTRACT Background To achieve adequate symptom control, patients with allergic rhinitis (AR) often need to increase their medication dose or add other treatments (co‐medication). We aimed to perform a systematic review to compare the efficacy and safety of AR medications for increased dose versus co‐medication.
Bernardo Sousa‐Pinto   +44 more
wiley   +1 more source

Kvinnelige førsteamanuensers relasjon til og reorientering i arbeidet sitt etter sykmelding

open access: yesTidsskrift for Kjønnsforskning
I denne artikkelen setter vi søkelyset på hvordan et utvalg kvinnelige førsteamanuenser tenker om og reorienterer sitt arbeid etter en eller flere perioder med sykmelding.
Tale Steen-Johnsen   +3 more
doaj   +1 more source

Immune checkpoint inhibitor‐induced arrhythmias: Mechanistic insights from clinical and preclinical studies

open access: yesBritish Journal of Pharmacology, EarlyView.
Immune checkpoint inhibitors (ICIs) have transformed cancer therapy, but their efficacy continues to be limited by immune‐related adverse events. Among these, ICI‐induced cardiac arrhythmias are increasingly recognised as a major adverse reaction, encompassing a broad spectrum of clinical phenotypes, including conduction blocks, atrial fibrillation and
Anand R. Ramalingam   +3 more
wiley   +1 more source

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