The proprotein convertase encoded by amontillado (amon) is required in Drosophila corpora cardiaca endocrine cells producing the glucose regulatory hormone AKH. [PDF]
Peptide hormones are potent signaling molecules that coordinate animal physiology, behavior, and development. A key step in activation of these peptide signals is their proteolytic processing from propeptide precursors by a family of proteases, the ...
Jeanne M Rhea +2 more
doaj +3 more sources
Insight Into Mosquito GnRH-Related Neuropeptide Receptor Specificity Revealed Through Analysis of Naturally Occurring and Synthetic Analogs of This Neuropeptide Family [PDF]
Adipokinetic hormone (AKH), corazonin (CRZ), and the AKH/CRZ-related peptide (ACP) are neuropeptides considered homologous to the vertebrate gonadotropin-releasing hormone (GnRH).
Azizia Wahedi +2 more
doaj +3 more sources
Sequence, characterization and pharmacological analyses of the adipokinetic hormone receptor in the stick insect, Carausius morosus [PDF]
BackgroundAdipokinetic/hypertrehalosaemic hormone (AKH/HrTH), corazonin (Crz) and the AKH/Crz-related peptide (ACP) are neuropeptides considered homologous to the vertebrate gonadotropin-releasing hormone (GnRH).
Gerd Gäde +5 more
doaj +2 more sources
Cardiac neurons expressing a glucagon-like receptor mediate cardiac arrhythmia induced by high-fat diet in Drosophila [PDF]
Cardiac arrhythmia leads to increased risks for stroke, heart failure, and cardiac arrest. Arrhythmic pathology is often rooted in the cardiac conduction system, but the mechanism is complex and not fully understood.
Yunpo Zhao +3 more
doaj +2 more sources
Metabolism, growth, and development are intrinsically linked, and their coordination is dependent upon inter-organ communication mediated by anabolic, catabolic, and steroid hormones.
MaryJane Shimell, Michael B O'connor
exaly +3 more sources
R1: إنشاء وتنقية متواليات الببتيد العصبي تم البحث في عائلات الببتيد العصبي LW و APGW و RPCH و AKH و CRZ و GnRH في قاعدة بيانات GenBank باستخدام 10 كلمات رئيسية: اسم الببتيد العصبي، واختصار السلائف، والاسم الكامل للسلائف، والاسم الكامل للسلائف مع كلمة "preropeptide"، ومجموعات هذه المصطلحات.
Cristian E. Cadena-Caballero +10 more
+7 more sources
Akhirin Functions as an Innate Immune Barrier to Preserve Neurogenic Niche Homeostasis During Mouse Brain Development [PDF]
Neurogenesis is tightly regulated by complex interactions among neural stem and progenitor cells (NSCs/NPCs), blood vessels, microglia, and extracellular matrix components within the neurogenic niche.
Mikiko Kudo +11 more
doaj +2 more sources
Peroxisomal ERK mediates Akh/glucagon action and glycemic control
The enhanced response of glucagon and its Drosophila homolog, adipokinetic hormone (Akh), leads to high-caloric-diet-induced hyperglycemia across species. While previous studies have characterized regulatory components transducing linear Akh signaling promoting carbohydrate production, the spatial elucidation of Akh action at the organelle level still ...
Dao-Jun Cheng, Wei Song
exaly +3 more sources
Akh Purattim ou « les rives de l'Eupkrate » est une des expressions utilisées au xviiie siècle av. J.-C. pour désigner le royaume de Mari, qui s’étendait de la confluence du Khabour au verrou de Bagbouz, actuellement à la frontière syro-irakienne. La série ainsi dénommée, précisée par son sous-titre Mémoires d’archéologie et d’histoire régionales ...
Margueron, Jean-Claude +3 more
+6 more sources
Structure–activity studies of Drosophila adipokinetic hormone (AKH) by a cellular expression system of dipteran AKH receptors [PDF]
Structure-activity studies for the adipokinetic hormone receptor of insects were for the first time performed in a cellular expression system. A series of single amino acid replacement analogues for the endogenous adipokinetic hormone of Drosophila melanogaster (pGlu-Leu-Thr-Phe-Ser-Pro-Asp-Trp-NH(2)) were screened for activity with a bioluminescence ...
Caers, Jelle +5 more
openaire +4 more sources

