Results 11 to 20 of about 5,745 (175)
Cardiac neurons expressing a glucagon-like receptor mediate cardiac arrhythmia induced by high-fat diet in Drosophila [PDF]
eLifeCardiac arrhythmia leads to increased risks for stroke, heart failure, and cardiac arrest. Arrhythmic pathology is often rooted in the cardiac conduction system, but the mechanism is complex and not fully understood.
Yunpo Zhao +3 more
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Sequence, characterization and pharmacological analyses of the adipokinetic hormone receptor in the stick insect, Carausius morosus [PDF]
Frontiers in EndocrinologyBackgroundAdipokinetic/hypertrehalosaemic hormone (AKH/HrTH), corazonin (Crz) and the AKH/Crz-related peptide (ACP) are neuropeptides considered homologous to the vertebrate gonadotropin-releasing hormone (GnRH).
Gerd Gäde +5 more
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Frontiers in Physiology, 2021 Metabolism, growth, and development are intrinsically linked, and their coordination is dependent upon inter-organ communication mediated by anabolic, catabolic, and steroid hormones.
Michael O'Connor +2 more
exaly +3 more sources
Akhirin Functions as an Innate Immune Barrier to Preserve Neurogenic Niche Homeostasis During Mouse Brain Development [PDF]
CellsNeurogenesis is tightly regulated by complex interactions among neural stem and progenitor cells (NSCs/NPCs), blood vessels, microglia, and extracellular matrix components within the neurogenic niche.
Mikiko Kudo +11 more
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Peroxisomal ERK mediates Akh/glucagon action and glycemic control
Cell Reports, 2023 The enhanced response of glucagon and its Drosophila homolog, adipokinetic hormone (Akh), leads to high-caloric-diet-induced hyperglycemia across species. While previous studies have characterized regulatory components transducing linear Akh signaling promoting carbohydrate production, the spatial elucidation of Akh action at the organelle level still ...
Daojun Cheng, Wei Song, Tujing Zhao
exaly +3 more sources
European Journal of Entomology, 2004 The aim of this study was to show that the kind of AKH-mobilized energy substrates in insects can be predicted on the basis of the results obtained with the application of heterologous, i.e. inter-species, AKHs.
Dalibor Kodrík +2 more
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Dietary amino acids promote glucagon-like hormone release to generate global calcium waves in adipose tissues in Drosophila [PDF]
Nature CommunicationsPropagation of intercellular calcium waves through tissues has been found to coordinate different multicellular responses. Nevertheless, our understanding of how calcium waves operate remains limited.
Muhammad Ahmad +7 more
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Elimination of certain honeybee venom activities by adipokinetic hormone [PDF]
Scientific ReportsThe primary aim of this study was to analyse the influence of honeybee venom on various aspects of Drosophila melanogaster physiology and to assess the efficacy of adipokinetic hormone (AKH) in mitigating venom toxicity.
Jan Černý +4 more
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A tumor-secreted protein utilizes glucagon release to cause host wasting [PDF]
Cell DiscoveryTumor‒host interaction plays a critical role in malignant tumor-induced organ wasting across multiple species. Despite known regulation of regional wasting of individual peripheral organs by tumors, whether and how tumors utilize critical host catabolic ...
Guangming Ding +12 more
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Electronic Journal of Plant Breeding, 2021 The present investigation was carried out to assess the stability of three lines, twelve testers, thirty six hybrids and one check (PKV Hy 2) over three locations in Maharashtra viz., Akola, Amravati and Nagpur using Eberhart and Russell Model ...
H. B. Kumbhalkar1*, V. L. Gawande2 , S. B. Deshmukh3 , Vinita Gotmare1 and V. N. Waghmare1
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